Safety assessment for EU DEMO – Achievements and open issues in view of a generic site safety report

2020 ◽  
Vol 155 ◽  
pp. 111541 ◽  
Author(s):  
Maria Teresa Porfiri ◽  
Neill Taylor ◽  
Sergio Ciattaglia ◽  
Xue Zhou Jin ◽  
Jane Johnston ◽  
...  
1984 ◽  
Vol 3 (3) ◽  
pp. 139-155 ◽  

A literature review of test data that have become available since the 1979 toxicological safety report on 2-Bromo-2-Nitropropane-1,3-Diol (BNPD) is presented and discussed. The earlier conclusion that BNPD is safe as a cosmetic ingredient at concentrations up to 0.1% except under circumstances where its action with amines or amides can result in the formation of nitrosamines or nitrosamides is reaffirmed. The new data suggest the possibility that when it is absorbed, this ingredient may contribute to endogenous formation of nitrosamines in humans.


2019 ◽  
Vol 25 ◽  
pp. 173
Author(s):  
Magnus Löndahl ◽  
Mona Landin-Olsson ◽  
Stig Attval ◽  
Colleen Mdingi ◽  
Katherine S Tweden
Keyword(s):  

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