Encephalopathy associated with autoimmune thyroid disease (Hashimoto's thyroiditis) presenting as depression: a case report

2011 ◽  
Vol 33 (6) ◽  
pp. 641.e7-641.e9 ◽  
Author(s):  
Chao-Yu Liu ◽  
Mei-Chih Meg Tseng ◽  
Po-Hsien Lin
Keyword(s):  
Case Report ◽  
Thyroid Disease ◽  
Hashimoto’S Thyroiditis ◽  
Autoimmune Thyroid Disease ◽  
Hashimoto's Thyroiditis ◽  
Autoimmune Thyroid

scholarly journals Advances in Research on the Role of Chemokines in Occurrence and Development of Autoimmune Thyroid Disease

2015 ◽  
Vol 4 (3) ◽  
pp. 59-63
Author(s):  
Guang Ji
Keyword(s):  
Thyroid Disease ◽  
Hashimoto’S Thyroiditis ◽  
Autoimmune Thyroid Disease ◽  
Hashimoto's Thyroiditis ◽  
Graves Disease ◽  
Neutrophil Chemotaxis ◽  
Autoimmune Thyroid

AbstractChemokines can be divided into four categories: α, β, γ, and δ. Chemokine α is related to neutrophil chemotaxis. Chemokine β is correlated with adsorption of monocytes, basophils, and eosinophils. Chemokine γ is mainly a lymphocyte chemokine. Function of chemokine δ remains unclear. Chemokines α and β are primarily related to occurrence and development of autoimmune thyroid disease. This study reviews chemokines and their receptors that are related to Graves’ disease and Hashimoto’s thyroiditis.

scholarly journals No association of two Fas gene polymorphisms with Hashimoto's thyroiditis and Graves' disease

2003 ◽  
pp. 393-396 ◽  
Author(s):  
BJ Stuck ◽  
MA Pani ◽  
F Besrour ◽  
M Segni ◽  
M Krause ◽  
...  
Keyword(s):  
Thyroid Disease ◽  
Genetic Risk ◽  
Hashimoto’S Thyroiditis ◽  
Gene Polymorphisms ◽  
Autoimmune Thyroid Disease ◽  
Fas Ligand ◽  
Hashimoto's Thyroiditis ◽  
Graves Disease ◽  
Autoimmune Thyroid ◽  
Hla Dq

BACKGROUND: Apoptosis is a joint pathogenic process underlying autoimmune thyroid disease. Increased programmed cell death in thyrocytes causes hypothyroidism in Hashimoto's thyroiditis, whereas in Graves' disease infiltrating lymphocytes undergo apoptosis while thyrocytes appear to proliferate under protection of anti-apoptotic signals. The Fas/Fas ligand cascade represents a major pathway initiating apoptosis. Its role in autoimmunity is well studied and genetic polymorphisms in gene loci of Fas and its ligand have been shown to be associated with autoimmune diseases. OBJECTIVE: Due to the functional relevance of the Fas pathway in autoimmune thyroid disease we were interested in the possible contribution of polymorphisms in the Fas gene to the genetic risk of thyroid autoimmunity, which so far is mainly, but incompletely, attributed to the HLA DQ region and polymorphisms in the CTLA-4 gene. DESIGN: We genotyped Caucasian families with at least one offspring affected by Hashimoto's thyroiditis (n=95) and Graves' disease (n=109) for two Fas gene polymorphisms (g-670 G-->A in the promoter region, g-154 C-->T in exon 7). METHODS: Extended transmission disequilibrium and chi(2) testing were performed. RESULTS: Neither polymorphism alone (P=0.44 and P=0.70) nor the promoter/exon 7 haplotypes (P=0.86) were associated with Hashimoto's thyroiditis. No association with Graves' disease was observed for the promoter polymorphism (P=0.91) and exon 7 (P=0.65) or the promoter/exon 7 haplotypes (P=0.80). CONCLUSION: In summary, our data do not suggest any significant contribution of common genetic Fas variants to the genetic risk of developing Hashimoto's thyroiditis or Graves' disease.

scholarly journals Screening of celiac disease in patients with autoimmune thyroid disease from Southern Brazil

2014 ◽  
Vol 58 (6) ◽  
pp. 625-629 ◽  
Author(s):  
Laila M. Teixeira ◽  
Renato Nisihara ◽  
Shirley Ramos da Rosa Utiyama ◽  
Ricardo S. de Bem ◽  
Cristina Marcatto ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Thyroid Disease ◽  
Hashimoto’S Thyroiditis ◽  
Autoimmune Thyroid Disease ◽  
Gastrointestinal Symptoms ◽  
University Hospital ◽  
Hashimoto's Thyroiditis ◽  
Upper Gastrointestinal Endoscopy ◽  
Southern Brazil ◽  
Autoimmune Thyroid

Objective: The objective of this study was to determine the prevalence of celiac disease (CD) in adults with autoimmune thyroid disease (ATD) from the endocrinology outpatient setting in a university hospital in Southern Brazil. Subjects and methods: From the years 2007 to 2011, 254 patients with ATD were enrolled consecutively, Grave’s disease was diagnosed in 143 (56.3%) and Hashimoto’s thyroiditis in 111 (43.7%) of them. All patients answered a questionnaire related to symptoms that could be associated with CD and serum samples to screen for IgA anti-endomysial (EmA-IgA) were collected. EmA-IgA-positive patients were offered upper gastrointestinal endoscopy and biopsy of duodenum. Results: A total of 254 patients were included; 222 (87.4%) female, mean age 45.4 ± 13.43 years (18 to 79 years). EmA-IgA was positive in seven patients (2.7%) and five done endoscopy with biopsy. Of these, three diagnosis of CD was confirmed (1.2%). All the three patients with CD had higher EmA-IgA titration, were female and had Hashimoto’s thyroiditis. Like other patients with ATD, CD patients had nonspecific gastrointestinal symptoms, such as heartburn and gastric distention. In our study, one in each 85 patients confirmed the diagnosis of CD. Conclusion: We found a prevalence of 1.2% (1:85) of confirmed CD among Brazilian patients with ATD. Although some IgA-EmA positive patients had Graves’ disease and one was male, all three patients with confirmed CD were female and had Hashimoto’s thyroiditis. Arq Bras Endocrinol Metab. 2014;58(6):625-9

Alopecia in preexisting autoimmune thyroid disease in family medicine practice: can hyperprolactinemia induce hair loss? A case report

2021 ◽  
Vol 30 (2) ◽  
Author(s):  
Zvonimir Bosnić ◽  
Blaženka Šarić ◽  
Domagoj Vučić ◽  
Božidar Kovačević ◽  
Nikica Marinić ◽  
...  
Keyword(s):  
Case Report ◽  
Family Medicine ◽  
Hair Loss ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Autoimmune Thyroid

scholarly journals A Case Report on Autoimmune Thyroid Disease (ATD) Associated with Chronic Angioedema

2021 ◽  
pp. 10-13
Author(s):  
K. Shivaraju ◽  
Mandhala Saikrishna ◽  
Billakuduru Srija ◽  
Akhil Aakunuri
Keyword(s):  
Internal Medicine ◽  
Case Report ◽  
Blood Vessels ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Rare Condition ◽  
Thyroid Peroxidase ◽  
Autoimmune Thyroid ◽  
One Year ◽  
Surrounding Skin

Angioedema may be a rare condition that manifests itself by abrupt localized edema caused by the fluid outflow from blood vessels into surrounding skin and tissue. This case report presents a 54-year old male patient with chronic angioedema (lip) for one year without urticaria. Six months ago, he approached the local clinic and used regular antihistamines by the physician advice. Still, there was no improvement in patient condition. Then he came to the outpatient department of internal medicine of our hospital. Therefore, we have done a series of investigations, in then he diagnosed with Hypothyroidism (TSH 8.05UIu/ml). Then he has prescribed levothyroxine 25mcg. After one month's review, he examined for Anti-thyroid peroxidase antibodies (Anti-TPO). In that examination, those were positive or elevated (mild). According to our research, this may probably be the first autoimmune thyroid disease associated with chronic angioedema without urticaria or hives.

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