ID: 3525541 FINAL PATHOLOGIC STAGING OF PATIENTS WITH SUSPECTED T1 COLORECTAL CARCINOMA WITH FULL THICKNESS RESECTION (FTR): A SINGLE CENTER NORTH AMERICAN EXPERIENCE

Abstract Background and study aims Endoscopic full-thickness resection (eFTR) allows en-bloc and transmural resection of colorectal lesions for which other advanced endoscopic techniques are unsuitable. We present our experience with a novel “clip first, cut later” eFTR-device and evaluate its indications, efficacy and safety. Patients and methods From July 2015 through October 2017, 51 eFTR-procedures were performed in 48 patients. Technical success and R0-resection rates were prospectively recorded and retrospectively analyzed. Results Indications for eFTR were non-lifting adenoma (n = 19), primary resection of malignant lesion (n = 2), resection of scar tissue after incomplete endoscopic resection of low-risk T1 colorectal carcinoma (n = 26), adenoma involving a diverticulum (n = 2) and neuroendocrine tumor (n = 2). Two lesions were treated by combining endoscopic mucosal resection and eFTR. Technical success was achieved in 45 of 51 procedures (88 %). Histopathology confirmed full-thickness resection in 43 of 50 specimens (86 %) and radical resection (R0) in 40 procedures (80 %). eFTR-specimens, obtained for indeterminate previous T1 colorectal carcinoma resection, were free of residual carcinoma in 25 of 26 cases (96 %). In six patients (13 %) a total of eight adverse events occurred within 30 days after eFTR. One perforation occurred, which was corrected endoscopically. No emergency surgery was necessary. Conclusion In this study eFTR appears to be safe and effective for the resection of colorectal lesions. Technical success, R0-resection and major adverse events rate were reasonable and comparable with eFTR data reported elsewhere. Mean specimen diameter (23 mm) limits its use to relatively small lesions. A clinical algorithm for eFTR case selection is proposed. eFTR ensured local radical excision where other endoscopic techniques did not suffice and reduced the need for surgery in selected cases.

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Sa1973 ENDOSCOPIC FULL-THICKNESS COLON RESECTION USING A NOVEL OVER-THE-SCOPE DEVICE: INITIAL NORTH-AMERICAN EXPERIENCE

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2018.04.1587 ◽

2018 ◽

Vol 87 (6) ◽

pp. AB272

Author(s):

Srihari Mahadev ◽

Gregory B. Haber ◽

Mitch A. Garcia ◽

Poi Yu Sofia Yuen ◽

Kristen Koller

Keyword(s):

North American ◽

Colon Resection ◽

Full Thickness ◽

American Experience

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Single-center North American Experience With Wolf Piezolith 3000 in Management of Urinary Calculi

Urology ◽

10.1016/j.urology.2008.06.013 ◽

2009 ◽

Vol 73 (5) ◽

pp. 958-963 ◽

Cited By ~ 6

Author(s):

Rou Wang ◽

Gary J. Faerber ◽

William W. Roberts ◽

David S. Morris ◽

J. Stuart Wolf

Keyword(s):

North American ◽

Urinary Calculi ◽

Single Center ◽

American Experience

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Pseudo cryomapping for ablation of atrioventricular nodal reentry tachycardia: A single center North American experience

Indian Pacing and Electrophysiology Journal ◽

10.1016/j.ipej.2016.12.007 ◽

2017 ◽

Vol 17 (4) ◽

pp. 95-99 ◽

Cited By ~ 1

Author(s):

Vaibhav K. Moondra ◽

Mark L. Greenberg ◽

Barbara R. Gerling ◽

Peter T. Holzberger ◽

Steven N. Weindling ◽

...

Keyword(s):

North American ◽

Single Center ◽

American Experience ◽

Atrioventricular Nodal Reentry Tachycardia ◽

Reentry Tachycardia

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Origins and Evolution of the North American Stable Peace

The Oxford Handbook of Peaceful Change in International Relations ◽

10.1093/oxfordhb/9780190097356.013.36 ◽

2020 ◽

Author(s):

David G. Haglund

Keyword(s):

International Relations ◽

North American ◽

Western Europe ◽

Regional Security ◽

Interstate Relations ◽

American Experience ◽

Back Seat ◽

The North ◽

Security Communities ◽

Primary Focus

Interstate relations among the North American countries have been irenic for so long that the continent is often assumed to have little if anything to contribute to scholarly debates on peaceful change. In good measure, this can be attributed to the way in which discussions of peaceful change often become intertwined with a different kind of inquiry among international relations scholars, one focused upon the origins and denotative characteristics of “pluralistic security communities.” Given that it is generally (though not necessarily accurately) considered that such security communities first arose in Western Europe, it is not difficult to understand why the North American regional-security story so regularly takes an analytical back seat to what is considered to be the far more interesting European one. This article challenges the idea that there is little to learn from the North American experience, inter alia by stressing three leading theoretical clusters within which can be situated the scholarly corpus of works attempting to assess the causes of peaceful change on the continent. Although the primary focus is on the Canada–US relationship, the article includes a brief discussion of where Mexico might be said to fit in the regional-security order.

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