scholarly journals Utility of fetal autopsy findings to estimate time of intrauterine fetal demise in maternal trauma

2022 ◽  
Vol 27 ◽  
pp. 300586
Author(s):  
Daniel S. Atherton ◽  
Brandi C. McCleskey ◽  
Virginia E. Duncan
Keyword(s):  
Maternal Trauma ◽  
Fetal Demise ◽  
Fetal Autopsy ◽  
Autopsy Findings ◽  
Intrauterine Fetal Demise

Florid Bacillus cereus Infection of the Placenta Associated With Intrauterine Fetal Demise

2021 ◽  
pp. 109352662199902
Author(s):  
Stephanie Shea ◽  
Alberto Paniz-Mondolfi ◽  
Emilia Sordillo ◽  
Michael Nowak ◽  
Fumiko Dekio
Keyword(s):  
Bacillus Cereus ◽  
Placental Tissue ◽  
Maternal Blood ◽  
Gastrointestinal Infections ◽  
Gram Positive ◽  
Fetal Demise ◽  
Placental Infection ◽  
Intrauterine Fetal Demise ◽  
Acute Necrotizing ◽  
Poor Outcomes

Bacillus cereus is a gram-positive, rod-shaped bacterium that is commonly implicated in foodborne illness but has also become increasingly recognized as a source of serious non-gastrointestinal infections, including sepsis, meningitis, and pneumonia. Non-gastrointestinal B. cereus infections have been identified in children, especially in neonates; however, there are no previously described cases of fetal demise associated with B. cereus placental infection. We present a case of acute chorioamnionitis-related intrauterine fetal demise of twin A at 17 weeks gestation, noted two days after selective termination of twin B. Histological examination revealed numerous gram-positive bacilli in placental tissue, as well as fetal vasculature, in the setting of severe acute necrotizing chorioamnionitis and subchorionitis, intervillous abscesses, acute villitis, and peripheral acute funisitis. Cultures of maternal blood and placental tissue both yielded growth of B. cereus. This case underscores the importance of B. cereus as a human pathogen, and specifically demonstrates its potential as an agent of severe intraamniotic and placental infection with poor outcomes for the fetus.

Three Cases with Cavitary Lesions in a Twin Gestation Complicated by a Single Intrauterine Fetal Demise

1993 ◽  
Vol 13 (4) ◽  
pp. 269-275
Author(s):  
Kimiko Tamagawa ◽  
Ryoko Ishibashi ◽  
Yoshihiko Mizuno ◽  
Kazuhiko Komiya ◽  
Masaya Oda ◽  
...  
Keyword(s):  
Fetal Demise ◽  
Intrauterine Fetal Demise

Intrauterine Fetal Demise, Male Fetuses (Monozygotic Twins)

2006 ◽  
Vol 130 (6) ◽  
pp. e90-e92
Author(s):  
Jane Ellaine Tongson-Ignacio ◽  
Zahida Parveen ◽  
Karen Thompson ◽  
John M. Hardman
Keyword(s):  
Monozygotic Twins ◽  
Fetal Demise ◽  
Intrauterine Fetal Demise

scholarly journals Investigating Mechanisms of Stillbirth in the Setting of Prenatal Substance Use

2018 ◽  
Vol 8 (4) ◽  
pp. 865-873
Author(s):  
Corrie B. Miller ◽  
Tricia Wright
Keyword(s):  
Substance Use ◽  
Adverse Pregnancy Outcome ◽  
Common Finding ◽  
In Utero Exposure ◽  
Toxic Substances ◽  
Fetal Demise ◽  
Search Terms ◽  
Intrauterine Fetal Demise ◽  
Adverse Pregnancy ◽  
Prenatal Substance Use

Introduction: Intrauterine fetal demise affects between 0.4-0.8% of pregnancies worldwide. This significant adverse pregnancy outcome continues to be poorly understood. In utero exposure to substances increases the risk of stillbirth to varying degrees according to the type of substance and degree of exposure. The aim of this qualitative narrative review is to investigate common biologic relationships between stillbirth and maternal substance use. Methods: A PubMed literature search was conducted to query the most commonly used substances and biologic mechanisms of stillbirth. Search terms included “stillbirth,” “intrauterine fetal demise,” “placenta,” “cocaine,” “tobacco,” “alcohol,” “methamphetamines,” “opioids/ opiates,” and “cannabis.” Results: There are very few studies identifying a direct link between substance use and stillbirth. Several studies demonstrate associations with placental lesions of insufficiency including poor invasion, vasoconstriction, and sequestration of toxic substances that inhibit nutrient transport. Restricted fetal growth is the most common finding in pregnancies complicated by all types of substance use. Discussion: More research is needed to understand the biologic mechanisms of stillbirth. Such knowledge will be foundational to understanding how to prevent and treat the adverse effects of substances during pregnancy.

Intrauterine fetal demise

2010 ◽  
pp. 236-240
Author(s):  
Leroy C Edozien
Keyword(s):  
Fetal Demise ◽  
Intrauterine Fetal Demise

Umbilical Cord Lesions in Early Intrauterine Fetal Demise

2003 ◽  
Vol 127 (7) ◽  
pp. 850-853 ◽  
Author(s):  
Vivekanand Singh ◽  
Sufia Khanum ◽  
Meenal Singh
Keyword(s):  
Umbilical Cord ◽  
Spontaneous Abortions ◽  
Fetal Demise ◽  
Amniotic Band ◽  
Early Gestation ◽  
Intrauterine Fetal Demise ◽  
Products Of Conception ◽  
Medical Induction ◽  
Umbilical Cords ◽  
Routine Assessment

Abstract Context.—The cause for intrauterine fetal demise (IUFD) occurring in early gestation in a high percentage of spontaneous abortions is unknown. Objective.—To determine the association, if any, of umbilical cord abnormalities with early IUFD. Design.—All cases of IUFD occurring within 16 weeks of gestation that presented to our hospitals between August 1998 and July 2001 were prospectively studied. Once the fetal demise was diagnosed, pregnancy was terminated by medical induction, such that the products of conception were largely delivered intact. Cases with an intact umbilical cord connecting the fetus and placenta were considered in the study, whereas disrupted cord and curettage material was excluded from the study. Results.—A total of 153 early IUFD cases were seen during the period of study. The medical induction yielded intact products of conception in 122 cases, whereas 31 cases had to be completed by curettage, as the expulsion of the conceptus was incomplete. Thirteen of the 122 IUFD cases showed abnormalities of the umbilical cord. The cord lesions most frequently encountered were constriction and coiling abnormalities. Other lesions seen included hemorrhage, thrombosis, edema, and amniotic band. Conclusions.—A significantly high number (10.7%) of IUFD in early gestation are associated with umbilical cord abnormalities. Routine assessment of umbilical cords in early pregnancy might help to detect pregnancies at risk.

Intrauterine Fetal Demise

2020 ◽  
Author(s):  
Gianna L Wilkie ◽  
Sarah E Little
Keyword(s):  
Risk Factors ◽  
Heart Rate ◽  
Umbilical Cord ◽  
Fetal Death ◽  
Genetic Evaluation ◽  
Placental Pathology ◽  
Fetal Demise ◽  
Maternal History ◽  
Intrauterine Fetal Demise ◽  
Delivery Planning

Intrauterine fetal demise (IUFD) and stillbirth are interchangeable terms to describe a fetal death in the second half of pregnancy. IUFD is defined as the delivery of a fetus showing no signs of life as indicated by the absence of heart rate, breathing, umbilical cord pulsation, or voluntary muscle movements. A thorough evaluation of maternal history and risk factors, fetal evaluation involving autopsy and genetic evaluation, and placental pathology should be offered at the time of IUFD diagnosis. Significant counseling should be provided to patients regarding future pregnancies and the risk of recurrence as well as the need for increased antenatal testing and delivery planning in subsequent pregnancies.  This review contains 5 tables, 10 figures and 55 references.  Keywords: fetal kick counts, intrauterine fetal demise (IUFD), management of intrauterine fetal demise, microarray, placental pathology, risk factors for intrauterine fetal demise

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