Minor histocompatibility antigens HA-1 and HPA-5 polymorphism in HLA identical related bone marrow transplantation

2003 ◽  
Vol 64 (10) ◽  
pp. S57
Author(s):  
Maria Spyropoulou-Vlachou ◽  
Valia Kotzampasaki ◽  
Miltiadis Papadimitropoulos ◽  
Catherine Stavropoulos-Giokas
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Marrow Transplantation ◽  
Histocompatibility Antigens ◽  
Minor Histocompatibility Antigens ◽  
Related Bone Marrow

scholarly journals Recurrence of aplastic anemia following cyclophosphamide and syngeneic bone marrow transplantation: evidence for two mechanisms of graft failure

Blood ◽  
1985 ◽  
Vol 65 (3) ◽  
pp. 553-556 ◽  
Author(s):  
FR Appelbaum ◽  
MA Cheever ◽  
A Fefer ◽  
R Storb ◽  
ED Thomas
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Aplastic Anemia ◽  
Marrow Transplantation ◽  
Graft Failure ◽  
Host Cells ◽  
High Dose ◽  
Immunological Reactivity ◽  
Histocompatibility Antigens ◽  
Minor Histocompatibility Antigens

Abstract Two patients with aplastic anemia were treated with high-dose cyclophosphamide and marrow transplantation from their normal, genetically identical twin. Both patients rapidly recovered normal marrow function, but marrow failure recurred 13 and 18 months later. Because donor and host pairs were identical twins, these cases of graft failure could not have resulted from the usual cause of graft failure, ie, immunological reactivity of host cells against unshared minor histocompatibility antigens of the donor. These results imply that there are at least two mechanisms responsible for graft failure after marrow transplantation for severe aplastic anemia.

scholarly journals Recurrence of aplastic anemia following cyclophosphamide and syngeneic bone marrow transplantation: evidence for two mechanisms of graft failure

Blood ◽  
1985 ◽  
Vol 65 (3) ◽  
pp. 553-556
Author(s):  
FR Appelbaum ◽  
MA Cheever ◽  
A Fefer ◽  
R Storb ◽  
ED Thomas
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Aplastic Anemia ◽  
Marrow Transplantation ◽  
Graft Failure ◽  
Host Cells ◽  
High Dose ◽  
Immunological Reactivity ◽  
Histocompatibility Antigens ◽  
Minor Histocompatibility Antigens

Two patients with aplastic anemia were treated with high-dose cyclophosphamide and marrow transplantation from their normal, genetically identical twin. Both patients rapidly recovered normal marrow function, but marrow failure recurred 13 and 18 months later. Because donor and host pairs were identical twins, these cases of graft failure could not have resulted from the usual cause of graft failure, ie, immunological reactivity of host cells against unshared minor histocompatibility antigens of the donor. These results imply that there are at least two mechanisms responsible for graft failure after marrow transplantation for severe aplastic anemia.

scholarly journals Treatment of leukemia with partially matched related bone marrow transplantation

1997 ◽  
Vol 19 (5) ◽  
pp. 421-427 ◽  
Author(s):  
RK Munn ◽  
PJ Henslee-Downey ◽  
EH Romond ◽  
EJ Marciniak ◽  
DR Fleming ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Marrow Transplantation ◽  
Related Bone Marrow

Successful Matched Related Bone Marrow Transplantation in a Patient with Autosomal Dominant Interferon Gamma Receptor 1 Deficiency

2020 ◽  
Vol 40 (7) ◽  
pp. 1045-1047
Author(s):  
Christa S. Zerbe ◽  
Dimana Dimitrova ◽  
Juan J. Gea-Banacloche ◽  
Samantha Kreuzburg ◽  
Steven M. Holland ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Interferon Gamma ◽  
Marrow Transplantation ◽  
Autosomal Dominant ◽  
Gamma Receptor ◽  
Related Bone Marrow
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