Short- and Long-term Evaluation of Bioresorbable Scaffolds by Optical Coherence Tomography

AbstractThis is a prospective observational study to establish the short- and long-term repeatability of measurements of peripapillary optical coherence tomography angiography (OCTA) parameters in healthy eyes and identify factors affecting long-term repeatability. We enrolled 84 healthy eyes. Participants with a history of any ophthalmic disease (except high myopia) or intraocular surgery were excluded from the study. An experienced examiner performed OCTA using disc-centered 6 × 6 mm scans. All examinations were conducted twice at 5-min intervals at the initial visit and repeated at least 6 months later. For short-term repeatability, the coefficient of variation (CV) was 2.94–4.22% and the intraclass correlation coefficient (ICC) was 0.840–0.934. For long-term repeatability, the CV was 2.73–3.84% and the ICC was 0.737–0.934. Multivariate analyses showed that the axial length (AL) (B = 0.970; p = 0.002) and mean signal strength (SS) (B = − 2.028; p < 0.001) significantly affected long-term repeatability. Measurements of peripapillary OCTA parameters exhibited excellent short-term and good long-term repeatability in healthy individuals. The mean SS and AL affected long-term repeatability and should be considered while interpreting peripapillary OCTA images.

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LONG-TERM EVALUATION OF VITREOMACULAR TRACTION DISORDER IN SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY

Retina ◽

10.1097/iae.0b013e3181eef08c ◽

2011 ◽

Vol 31 (2) ◽

pp. 324-331 ◽

Cited By ~ 62

Author(s):

Dominik Odrobina ◽

Zofia Michalewska ◽

Janusz Michalewski ◽

Krzysztof Dzięgielewski ◽

Jerzy Nawrocki

Keyword(s):

Optical Coherence Tomography ◽

Spectral Domain ◽

Vitreomacular Traction ◽

Optical Coherence ◽

Term Evaluation

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Inner Retinal Morphology and Visual Outcomes in Idiopathic Epiretinal Membrane Surgery: A Retrospective Optical Coherence Tomography Study

Journal of VitreoRetinal Diseases ◽

10.1177/2474126421989614 ◽

2021 ◽

pp. 247412642198961

Author(s):

Ioannis S. Dimopoulos ◽

Michael Dollin

Keyword(s):

Optical Coherence Tomography ◽

Epiretinal Membrane ◽

Strong Predictor ◽

Plexiform Layer ◽

Inner Plexiform Layer ◽

Optical Coherence ◽

Visual Outcomes ◽

Retinal Pathology

Purpose: Epiretinal membrane (ERM) is a common retinal finding for patients older than 50 years. Disorganization of the retinal inner layers (DRIL) has emerged as a novel predictor of poor visual acuity (VA) in eyes with inner retinal pathology. The aim of our study is to correlate preoperative DRIL with visual outcomes after ERM surgery. Methods: Medical records and optical coherence tomography (OCT) images of 81 pseudophakic patients who underwent treatment of idiopathic ERM were reviewed. Preoperative DRIL on OCT was correlated with VA at baseline and at 3 and 6 months after ERM surgery. DRIL was defined as the loss of distinction between the ganglion cell–inner plexiform layer complex, inner nuclear layer, and outer plexiform layer. DRIL severity was based on its extent within the central 2-mm region of a transfoveal B-scan (absent/mild: <one-third, severe: >one-third horizontal width). Results: Review of preoperative OCT showed severe DRIL in 41% and absent/mild DRIL in 59%. Severe DRIL was associated with worse baseline VA ( P < .001). Preoperative VA and DRIL status at baseline were both predictors of postoperative VA at follow-up time points ( P < .001). Severe DRIL was associated with significantly less improvement in VA at 6 months (–0.23 logMAR for absent/mild vs –0.14 for severe DRIL). Conclusions: Presence of severe preoperative DRIL correlates with worse baseline VA in patients with ERM and reduced VA improvement at 6 months. DRIL can be a strong predictor of long-term poor visual outcomes in ERM surgery.

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The role of optical coherence tomography guidance in scaffold versus stent optimization

The Egyptian Heart Journal ◽

10.1186/s43044-020-00110-z ◽

2020 ◽

Vol 72 (1) ◽

Author(s):

Arif A. Al Nooryani ◽

Nagwa A. Abdelrahman ◽

Hatem A. Helmy ◽

Yehia T. Kishk ◽

Ayman K. M. Hassan

Keyword(s):

Decision Making ◽

Optical Coherence Tomography ◽

Coronary Intervention ◽

Drug Eluting Stents ◽

Optical Coherence ◽

Total Rate ◽

Great Ability ◽

Bioresorbable Scaffolds ◽

Drug Eluting ◽

The Impact

Abstract Background Optical coherence tomography showed a great ability to identify adverse features during percutaneous coronary intervention with drug-eluting stents and resulted in better clinical outcomes. The study aimed to assess the impact of optical coherence tomography on intraoperative decision-making during implantation of Absorb bioresorbable scaffolds versus everolimus drug-eluting stents. Results We performed an observational study that included 223 consecutive patients post optical coherence tomography-guided implantation of either Absorb bioresorbable scaffolds (162 patients) or everolimus drug-eluting stents (61 patients). We studied the influence of optical coherence tomography on intraoperative decision-making during implantation of bioresorbable scaffolds versus drug-eluting stents by analyzing the total rate of optical coherence tomography-dependent modifications in each device. After satisfactory angiographic results, the total rate of required intervention for optical coherence tomography detected complications was significantly higher in the bioresorbable scaffolds arm compared to drug-eluting stents arm (47.8% versus 32.9%, respectively; p = 0.019). The additional modifications encompassed further optimization in the case of device underexpansion or struts malapposition, and even stenting in the case of strut fractures, or significant edge dissection. Conclusions Compared to drug-eluting stents, Absord scaffold was associated with a significantly higher rate of optical coherence tomography-identified intraprocedural complications necessitating further modifications. The study provides some hints on the reasons of scaffolds failure in current PCI practice; it offers a new insight for the enhancement of BRS safety and presents and adds to the growing literature for successful BRS utilization.

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