Genetic variability of 17 Y chromosome STRs in two Native American populations from Argentina

2006 ◽  
Vol 1288 ◽  
pp. 154-155 ◽  
Author(s):  
U. Toscanini ◽  
L. Gusmão ◽  
G. Berardi ◽  
A. Amorim ◽  
A. Carracedo ◽  
...  
Keyword(s):  
Native American ◽  
Genetic Variability ◽  
Y Chromosome

scholarly journals Genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in Type 1 Diabetes from an admixed Brazilian population

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rossana Santiago de Sousa Azulay ◽  
Luís Cristóvão Porto ◽  
Dayse Aparecida Silva ◽  
Maria da Glória Tavares ◽  
Roberta Maria Duailibe Ferreira Reis ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Native American ◽  
Y Chromosome ◽  
Chromosome Analysis ◽  
Brazilian Population ◽  
Genetic Ancestry ◽  
Sample Sizes ◽  
Chromosome Markers ◽  
Hla Genotypes

AbstractThis study aimed to investigate the relationship between genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in patients with Type 1 Diabetes from an admixed Brazilian population. Inference of autosomal ancestry; HLA-DRB1, -DQA1 and -DQB1 typifications; and Y chromosome analysis were performed. European autosomal ancestry was about 50%, followed by approximately 25% of African and Native American. The European Y chromosome was predominant. The HLA-DRB1*03 and DRB1*04 alleles presented risk association with T1D. When the Y chromosome was European, DRB1*03 and DRB1*04 homozygote and DRB1*03/DRB1*04 heterozygote genotypes were the most frequent. The results suggest that individuals from Maranhão have a European origin as their major component; and are patrilineal with greater frequency from the R1b haplogroup. The predominance of the HLA-DRB1*03 and DRB1*04 alleles conferring greater risk in our population and being more frequently related to the ancestry of the European Y chromosome suggests that in our population, the risk of T1D can be transmitted by European ancestors of our process miscegenation. However, the Y sample sizes of Africans and Native Americans were small, and further research should be conducted with large mixed sample sizes to clarify this possible association.

scholarly journals Y Chromosome Sequences Reveal a Short Beringian Standstill, Rapid Expansion, and early Population structure of Native American Founders

2019 ◽  
Vol 29 (1) ◽  
pp. 149-157.e3 ◽  
Author(s):  
Thomaz Pinotti ◽  
Anders Bergström ◽  
Maria Geppert ◽  
Matt Bawn ◽  
Dominique Ohasi ◽  
...  
Keyword(s):  
Population Structure ◽  
Native American ◽  
Y Chromosome ◽  
Rapid Expansion

scholarly journals Y-chromosome biallelic polymorphisms and Native American population structure

2002 ◽  
Vol 66 (4) ◽  
pp. 255-259 ◽  
Author(s):  
M.-C. BORTOLINI ◽  
F. M. SALZANO ◽  
C. H. D. BAU ◽  
Z. LAYRISSE ◽  
M. L. PETZL-ERLER ◽  
...  
Keyword(s):  
Population Structure ◽  
Native American ◽  
Y Chromosome ◽  
American Population ◽  
Native American Population

Genetic Ancestry Inferred From Autosomal and Y Chromosome Markers and HLA Genotypes in Type 1 Diabetes From an Admixed Brazilian Population.

2021 ◽  
Author(s):  
Rossana Santiago de Sousa Azulay ◽  
Luís Cristóvão Porto ◽  
Dayse Aparecida Silva ◽  
Maria da Gloria Tavares ◽  
Roberta Dualibe ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Native American ◽  
Native Americans ◽  
Y Chromosome ◽  
Chromosome Analysis ◽  
Brazilian Population ◽  
Genetic Ancestry ◽  
Sample Sizes ◽  
Chromosome Markers

Abstract This study aimed to investigate the relationship between genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in patients with Type 1 Diabetes from an admixed Brazilian population. Inference of autosomal ancestry; HLA-DRB1, -DQA1 and -DQB1 typifications; and Y chromosome analysis were performed. European autosomal ancestry was about 50%, followed by approximately 25% of African and Native American. The European Y chromosome was predominant. The HLA-DRB1* 03 and DRB1* 04 alleles presented risk association with T1D. When the Y chromosome was European, DRB1*03 and DRB1*04 homozygote and DRB1*03/DRB1*04 heterozygote genotypes were the most frequent. The results suggest that individuals from Maranhão have a European origin as their major component; and are patrilineal with greater frequency from the R1b haplogroup. The predominance of the HLA-DRB1* 03 and DRB1* 04 alleles conferring greater risk in our population and being more frequently related to the ancestry of the European Y chromosome suggests that in our population, the risk of T1D can be transmitted by European ancestors of our process miscegenation. However, the Y sample sizes of Africans and Native Americans were small, and further research should be conducted with large mixed sample sizes to clarify this possible association.

Y chromosome polymorphisms in Native American and Siberian populations: identification of Native American Y chromosome haplotypes

1997 ◽  
Vol 100 (5-6) ◽  
pp. 536-543 ◽  
Author(s):  
Jeffrey T. Lell ◽  
Michael D. Brown ◽  
Theodore G. Schurr ◽  
R. I. Sukernik ◽  
Yelena B. Starikovskaya ◽  
...  
Keyword(s):  
Native American ◽  
Y Chromosome

Y chromosome microsatellite genetic variation in two Native American populations from Argentina: Population stratification and mutation data

2008 ◽  
Vol 2 (4) ◽  
pp. 274-280 ◽  
Author(s):  
Ulises Toscanini ◽  
Leonor Gusmão ◽  
Gabriela Berardi ◽  
António Amorim ◽  
Ángel Carracedo ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Native American ◽  
Y Chromosome ◽  
Population Stratification ◽  
Mutation Data

Rapid screening for Native American mitochondrial and Y-chromosome haplogroups detection in routine DNA analysis

2011 ◽  
Vol 5 (2) ◽  
pp. 105-108 ◽  
Author(s):  
Gala Zuccarelli ◽  
Evguenia Alechine ◽  
Mariela Caputo ◽  
Cecilia Bobillo ◽  
Daniel Corach ◽  
...  
Keyword(s):  
Native American ◽  
Y Chromosome ◽  
Dna Analysis ◽  
Rapid Screening
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