A physiologically based pharmacokinetics model for melatonin—Effects of light and routes of administration

Routes Of Administration ◽

Establishment of Dissolution Acceptance Criterion Using In Silico Physiologically Based Pharmacokinetics (PBPK) Modelling and Simulation

10.26226/morressier.57d6b2bed462b8028d88e0b5 ◽

2016 ◽

Author(s):

John Duan

Keyword(s):

In Silico ◽

Modelling And Simulation ◽

Pbpk Modelling ◽

Acceptance Criterion ◽

Predicting Pediatric Drug Disposition-Present and Future Directions of Pediatric Physiologically-Based Pharmacokinetics

Drug Metabolism Letters ◽

10.2174/1872312809666150602151429 ◽

2015 ◽

Vol 9 (2) ◽

pp. 80-87 ◽

Cited By ~ 3

Author(s):

Shogo Miyagi ◽

Janel Long-Boyle

Keyword(s):

Drug Disposition ◽

Pediatric Drug ◽

Future Directions ◽

Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice

Journal of Pharmaceutical Sciences ◽

10.1021/js9901763 ◽

1999 ◽

Vol 88 (12) ◽

pp. 1281-1287 ◽

Cited By ~ 74

Author(s):

Masami Kawahara ◽

Atsushi Sakata ◽

Toshiaki Miyashita ◽

Ikumi Tamai ◽

Akira Tsuji

Keyword(s):

Knockout Mice ◽

Application of the Tissue Composition–Based Model to Minipig for Predicting the Volume of Distribution at Steady State and Dermis-to-Plasma Partition Coefficients of Drugs Used in the Physiologically Based Pharmacokinetics Model in Dermatology

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2018.09.001 ◽

2019 ◽

Vol 108 (1) ◽

pp. 603-619 ◽

Cited By ~ 3

Author(s):

Patrick Poulin ◽

Severine H. Collet ◽

Nicolas Atrux-Tallau ◽

Jean-Michel Linget ◽

Laurent Hennequin ◽

...

Keyword(s):

Steady State ◽

Partition Coefficients ◽

Volume Of Distribution ◽

Tissue Composition ◽

Physiologically Based Pharmacokinetics and Pharmacodynamics of Skin

Dermal Absorption and Toxicity Assessment ◽

10.3109/9780849375927-15 ◽

2007 ◽

pp. 205-234

Keyword(s):

Pharmacokinetics And Pharmacodynamics ◽

Physiologically-Based Pharmacokinetics of Lysosomotropic Chloroquine in Rat and Man

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.120.000385 ◽

2020 ◽

pp. JPET-AR-2020-000385

Author(s):

Xin Liu ◽

William J Jusko

Keyword(s):

Physiologically-Based Pharmacokinetics and Molecular Pharmacodynamics of 17-(allylamino)-17-demethoxygeldanamycin and Its Active Metabolite in Tumor-Bearing Mice

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1023/a:1025542026488 ◽

2003 ◽

Vol 30 (3) ◽

pp. 185-219 ◽

Cited By ~ 44

Author(s):

Lu Xu ◽

Julie L. Eiseman ◽

Merrill J. Egorin ◽

David Z. D'Argenio

Keyword(s):

Active Metabolite ◽

Tumor Bearing ◽

Physiologically Based Pharmacokinetics: A Simple, All Purpose Model

Industrial & Engineering Chemistry Research ◽

10.1021/ie9015717 ◽

2010 ◽

Vol 49 (6) ◽

pp. 2969-2978 ◽

Cited By ~ 24

Author(s):

Michela Di Muria ◽

Gaetano Lamberti ◽

Giuseppe Titomanlio

Keyword(s):

Pharmacometrics, Physiologically Based Pharmacokinetics , Quantitative Systems Pharmacology— What's Next?—Joining Mechanistic and Epidemiological Approaches

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12425 ◽

2019 ◽

Vol 8 (6) ◽

pp. 352-355 ◽

Cited By ~ 3

Author(s):

Stephan Schmidt ◽

Sarah Kim ◽

Valvanera Vozmediano ◽

Rodrigo Cristofoletti ◽

Almut G. Winterstein ◽

...

Keyword(s):

Systems Pharmacology ◽

Quantitative Systems Pharmacology ◽

A Translational Physiologically Based Pharmacokinetics/Pharmacodynamics Framework of Target-Mediated Disposition, Target Inhibition and Drug–Drug Interactions of Bortezomib

The AAPS Journal ◽

10.1208/s12248-020-00448-x ◽

2020 ◽

Vol 22 (3) ◽

Author(s):

Shinji Iwasaki ◽

Andy Zhu ◽

Michael Hanley ◽

Karthik Venkatakrishnan ◽

Cindy Xia

Keyword(s):

Drug Interactions ◽