Application of the Tissue Composition–Based Model to Minipig for Predicting the Volume of Distribution at Steady State and Dermis-to-Plasma Partition Coefficients of Drugs Used in the Physiologically Based Pharmacokinetics Model in Dermatology

Patrick Poulin; Severine H. Collet; Nicolas Atrux-Tallau; Jean-Michel Linget; Laurent Hennequin; Claire E. Wilson

doi:10.1016/j.xphs.2018.09.001

Application of the Tissue Composition–Based Model to Minipig for Predicting the Volume of Distribution at Steady State and Dermis-to-Plasma Partition Coefficients of Drugs Used in the Physiologically Based Pharmacokinetics Model in Dermatology

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2018.09.001 ◽

2019 ◽

Vol 108 (1) ◽

pp. 603-619 ◽

Cited By ~ 3

Author(s):

Patrick Poulin ◽

Severine H. Collet ◽

Nicolas Atrux-Tallau ◽

Jean-Michel Linget ◽

Laurent Hennequin ◽

...

Keyword(s):

Steady State ◽

Partition Coefficients ◽

Volume Of Distribution ◽

Tissue Composition ◽

Physiologically Based Pharmacokinetics ◽

Physiologically Based

Download Full-text

Prediction of Tissue-Plasma Partition Coefficients Using Microsomal Partitioning: Incorporation into Physiologically based Pharmacokinetic Models and Steady-State Volume of Distribution Predictions

Drug Metabolism and Disposition ◽

10.1124/dmd.119.087973 ◽

2019 ◽

Vol 47 (10) ◽

pp. 1050-1060 ◽

Cited By ~ 1

Author(s):

Kimberly Holt ◽

Min Ye ◽

Swati Nagar ◽

Ken Korzekwa

Keyword(s):

Steady State ◽

Partition Coefficients ◽

Volume Of Distribution ◽

Pharmacokinetic Models ◽

Physiologically Based Pharmacokinetic Models ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

A Valid Equation for the Well-Stirred Perfusion Limited Physiologically Based Pharmacokinetic Model that Consistently Accounts for the Blood–Tissue Drug Distribution in the Organ and the Corresponding Valid Equation for the Steady State Volume of Distribution

Journal of Pharmaceutical Sciences ◽

10.1002/jps.21798 ◽

2010 ◽

Vol 99 (1) ◽

pp. 475-485 ◽

Cited By ~ 12

Author(s):

Leonid M. Berezhkovskiy

Keyword(s):

Steady State ◽

Pharmacokinetic Model ◽

Drug Distribution ◽

Volume Of Distribution ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

A Comment on the Application of Drug Tissue-Plasma Partition Coefficients Kp in Eliminating Organs to Calculation of Volume of Distribution at Steady State

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-005-0005-7 ◽

2005 ◽

Vol 32 (5-6) ◽

pp. 655-658 ◽

Cited By ~ 2

Author(s):

Sven Björkman

Keyword(s):

Steady State ◽

Partition Coefficients ◽

Volume Of Distribution

Download Full-text

Measurement of Binding of Basic Drugs to Acidic Phospholipids Using Surface Plasmon Resonance and Incorporation of the Data into Mechanistic Tissue Composition Equations to Predict Steady-State Volume of Distribution

Drug Metabolism and Disposition ◽

10.1124/dmd.111.040253 ◽

2011 ◽

Vol 39 (10) ◽

pp. 1789-1793 ◽

Cited By ~ 15

Author(s):

Helen Small ◽

Iain Gardner ◽

Hannah M. Jones ◽

John Davis ◽

Malcolm Rowland

Keyword(s):

Surface Plasmon Resonance ◽

Steady State ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Volume Of Distribution ◽

Basic Drugs ◽

Tissue Composition ◽

Acidic Phospholipids

Download Full-text

Concentration andpH dependent steady-state volume of distribution of methotrexate estimated by a simple physiologically based method

Journal of Pharmacokinetics and Biopharmaceutics ◽

10.1007/bf01059555 ◽

1984 ◽

Vol 12 (6) ◽

pp. 597-610 ◽

Cited By ~ 9

Author(s):

Chung Y. Lui ◽

Myung G. Lee ◽

Win L. Chiou

Keyword(s):

Steady State ◽

Volume Of Distribution ◽

Physiologically Based

Download Full-text

Simplified Physiologically Based Method to Estimate Steady-State Volume of Distribution

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600700841 ◽

1981 ◽

Vol 70 (8) ◽

pp. 967-968 ◽

Cited By ~ 5

Author(s):

Win L. Chiou ◽

Gilbert Lam

Keyword(s):

Steady State ◽

Volume Of Distribution ◽

Physiologically Based

Download Full-text

Establishment of Dissolution Acceptance Criterion Using In Silico Physiologically Based Pharmacokinetics (PBPK) Modelling and Simulation

10.26226/morressier.57d6b2bed462b8028d88e0b5 ◽

2016 ◽

Author(s):

John Duan

Keyword(s):

In Silico ◽

Modelling And Simulation ◽

Physiologically Based Pharmacokinetics ◽

Pbpk Modelling ◽

Acceptance Criterion ◽

Physiologically Based

Download Full-text

Predicting Pediatric Drug Disposition-Present and Future Directions of Pediatric Physiologically-Based Pharmacokinetics

Drug Metabolism Letters ◽

10.2174/1872312809666150602151429 ◽

2015 ◽

Vol 9 (2) ◽

pp. 80-87 ◽

Cited By ~ 3

Author(s):

Shogo Miyagi ◽

Janel Long-Boyle

Keyword(s):

Drug Disposition ◽

Physiologically Based Pharmacokinetics ◽

Pediatric Drug ◽

Future Directions ◽

Physiologically Based

Download Full-text

Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice

Journal of Pharmaceutical Sciences ◽

10.1021/js9901763 ◽

1999 ◽

Vol 88 (12) ◽

pp. 1281-1287 ◽

Cited By ~ 74

Author(s):

Masami Kawahara ◽

Atsushi Sakata ◽

Toshiaki Miyashita ◽

Ikumi Tamai ◽

Akira Tsuji

Keyword(s):

Knockout Mice ◽

Physiologically Based Pharmacokinetics ◽

Physiologically Based

Download Full-text

Estimation of statistical moments and steady-state volume of distribution for a drug given by intravenous infusion

Journal of Pharmacokinetics and Biopharmaceutics ◽

10.1007/bf01059037 ◽

1982 ◽

Vol 10 (5) ◽

pp. 551-558 ◽

Cited By ~ 24

Author(s):

Keith K. H. Chan ◽

Milo Gibaldi

Keyword(s):

Steady State ◽

Intravenous Infusion ◽

Volume Of Distribution ◽

Statistical Moments

Download Full-text