Implementation of Quality by Design (QbD) approach in development of silver sulphadiazine loaded egg oil organogel: An improved dermatokinetic profile and therapeutic efficacy in burn wounds

2020 ◽  
Vol 576 ◽  
pp. 118977 ◽  
Author(s):  
Kanika Thakur ◽  
Akanksha Mahajan ◽  
Gajanand Sharma ◽  
Bhupinder Singh ◽  
Kaisar Raza ◽  
...  
Burns ◽  
2020 ◽  
Author(s):  
Subhendu Khan ◽  
Jerry R. John ◽  
Ramesh K. Sharma

Burns ◽  
2016 ◽  
Vol 42 (7) ◽  
pp. 1377-1386 ◽  
Author(s):  
A. Heyneman ◽  
H. Hoeksema ◽  
D. Vandekerckhove ◽  
A. Pirayesh ◽  
S. Monstrey

Burns ◽  
2013 ◽  
Vol 39 (4) ◽  
pp. 754-759 ◽  
Author(s):  
B.K.H.L. Boekema ◽  
L. Pool ◽  
M.M.W. Ulrich

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Pawel Olczyk ◽  
Pawel Ramos ◽  
Katarzyna Komosinska-Vassev ◽  
Jerzy Stojko ◽  
Barbara Pilawa

Concentration and properties of free radicals in the burn wounds treated with propolis were examined by the use of electron paramagnetic resonance spectroscopy. Magnetic spin-spin interactions and complex free radicals structures in wound beds were studied. The results were compared to those obtained for silver sulphadiazine used as a standard pharmaceutical agent. The changes of free radicals in the matrix of injury with time of exposition on these substances were tested. The aim of this study was to check the hypothesis about the best influence of propolis on the burn wounds healing. It was confirmed that a relatively lower concentration of free radicals exists in the burn wounds treated with propolis. The homogeneously broadened spectra and a complex free radical system characterize the tested tissue samples. The fastening of spin-lattice relaxation processes in the matrix of injury after treatment with propolis and silver sulphadiazine was observed. Practical usefulness of electron paramagnetic resonance spectroscopy in alternative medicine was proved.


Burns ◽  
1977 ◽  
Vol 3 (2) ◽  
pp. 104-107 ◽  
Author(s):  
William W. Monafo ◽  
Vatche' H. Ayvazian ◽  
Ann Marie Skinner

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