A Study of Daily Localization with 3D Ultrasound, Cone Beam CT and Implanted Fiducial Markers for Patients undergoing IGRT for Prostate Cancer

2008 ◽  
Vol 72 (1) ◽  
pp. S564
Author(s):  
T. Neicu ◽  
T. Nurushev ◽  
R. Hammoud ◽  
F. Martin ◽  
D. Pradhan ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cone Beam Ct ◽  
3D Ultrasound ◽  
Cone Beam ◽  
Fiducial Markers

scholarly journals PTV margin definition in hypofractionated IGRT of localized prostate cancer using cone beam CT and orthogonal image pairs with fiducial markers

2014 ◽  
Vol 9 (1) ◽  
Author(s):  
Christoph Oehler ◽  
Stephanie Lang ◽  
Peter Dimmerling ◽  
Christian Bolesch ◽  
Stephan Kloeck ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cone Beam Ct ◽  
Localized Prostate Cancer ◽  
Cone Beam ◽  
Fiducial Markers ◽  
Ptv Margin ◽  
Image Pairs

INTRAFRACTIONAL PROSTATE SHIFTS DURING STEREOTACTIC RADIATION THERAPY

2017 ◽  
Vol 63 (2) ◽  
pp. 287-293
Author(s):  
Sergey Kanaev ◽  
Sergey Novikov ◽  
Roman Novikov ◽  
Yu. Melnik ◽  
N. Ilin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cone Beam Ct ◽  
Cone Beam ◽  
Stereotactic Radiation Therapy ◽  
Fiducial Markers ◽  
Dose Delivery ◽  
Stereotactic Radiation ◽  
Intrafraction Motion ◽  
Treatment Table ◽  
Anterior Posterior

In this study we analyzed prostate intrafraction motion during the course of stereotactic radiotherapy (STRT). STRT (5 fraction of 7.25Gy) was performed in 31 primary patients with prostate cancer. At least 3 gold fiducial markers were implanted in prostate of every patient 3-5 days before simulation. Prostate position on treatment table was verified with cone beam CT just before and immediately after the end of each radiotherapy session. This data help to determine prostate displacement in cranio-caudal, anterior-posterior and lateral axes. Average values of intra-fractional prostate displacement were as follows: 0,8+/-1,2mm - in cranio-caudal, 0.9+/-1,0mm - in lateral and 1.3+/-1,3mm - in anterior-posterior directions. In 5%-8,3% cases prostate displacement in cranio-caudal and lateral directions exceeded 2mm with maximal value of 5mm. In accordance with obtained average shifts we recommend following PTV margins: 1mm - in anterior-posterior and 3mm - in all other directions. In this case average intrafractional prostate shifts would not compromise dose delivery to prostate (V100 - 98%, D90 - 101%) and in comparison with standard (3mm, 5mm, 5mm, 5mm) margins would permit 16% reduction of rectum volume incorporated in 80% isodose. We propose that small average intrafractional displacement of prostate permits the use of narrower PTV margins without compromising coverage of the target and significant reduction of rectum volume covered by 80% isodose.

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