Patterns Of Failure For Adolescent And Young Adult Hodgkin Lymphoma Patients Treated With Radiotherapy In The Modern Era: A Multi-Institution Review

2020 ◽  
Vol 108 (3) ◽  
pp. e758-e759
Author(s):  
J.E. Bates ◽  
S.A. Terezakis ◽  
C.G. Morris ◽  
R. Mailhot Vega ◽  
N.P. Mendenhall ◽  
...  
2016 ◽  
Vol 173 (4) ◽  
pp. 503-504 ◽  
Author(s):  
Ross Pinkerton ◽  
Mitchell S. Cairo ◽  
Finbarr E. Cotter

2020 ◽  
Author(s):  
M Kamei ◽  
Y Koga ◽  
R Fukano ◽  
M Sekimizu ◽  
K Ohki ◽  
...  

2019 ◽  
Vol 185 (6) ◽  
pp. 1099-1110 ◽  
Author(s):  
Matthew J. Ehrhardt ◽  
Jessica Hochberg ◽  
Kari L. Bjornard ◽  
Tara M. Brinkman

2016 ◽  
Vol 34 (3_suppl) ◽  
pp. 107-107
Author(s):  
Erin Elizabeth Hahn ◽  
Yi-Lin Wu ◽  
Jazmine Garcia Delgadillo ◽  
Corrine E. Munoz-Plaza

107 Background: Adolescent and young adult (AYA) Hodgkin lymphoma survivors are at high risk for long-term and late effects. Post-treatment guidelines are available from the National Comprehensive Cancer Network (NCCN) and others; however, adherence to these guidelines is unknown. The purpose of this study was to identify AYA Hodgkin survivors from an integrated health care system and examine use of post-treatment services. Methods: We identified patients diagnosed between 2000 and 2010, ages 15 to 39. We identified use of NCCN recommended services (oncology visits, labs, CT) and non-recommended services (PET scan, CT after first year). Multivariate logistic regression was used to identify associations between receipt of recommended services within first 12 months post-treatment (oncology visits, labs, CT) and patient (gender, race/ethnicity) and cancer characteristics (stage, diagnosis age, diagnosis year). Results: We identified 354 patients (see table). Almost all had recommended oncology visits within the first 5 years (96%); 70% received recommended labs. Two-thirds received a recommended CT scan within 12 months post- treatment. However, 47% received a non-recommended CT in year 2 and 35% in year 3, and 33% received a non-recommended PETs. Overall, 48% received all recommended care within the first 12 months. Diagnosis year was significant in regression, with those diagnosed 2000-2005 less likely to receive recommended care than those diagnosed 2006-2010 (OR = 0.007, p < .0001). Conclusions: Less than half of patients received recommended care within the first year post-treatment. These results will inform development of effective programs to meet survivors’ needs. Next steps include exploring risk-stratified patterns of care in long-term survivors. [Table: see text]


2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e13630-e13630
Author(s):  
Eileen Yi Ling Poon ◽  
Evelyn Wong ◽  
Wei Lin Goh ◽  
Jiancheng Hong ◽  
Victoria Wong ◽  
...  

e13630 Background: Hematological malignancies is thought to be one of the more common Adolescent and Young Adult (AYA) cancers and constitute leukemias and lymphomas. However, little is known about its incidence and prevalence in Asia. We also do not have any data on its behavior or its prognosticators. The outcomes of this group of patients is also unknown when compared to the pediatrics or geriatrics, but is expected to be not as ideal. There is no consensus on whether this group of patients should be treated as pediatrics or as the older adults. We have sought to evaluate the prevalence and trends in a single large-volume tertiary cancer centre in Asia. Methods: We extracted data on all patients with cancer between 16-39 years old who were seen at our centre (National Cancer Centre Singapore) during the period of 1st January 2015 and 31st December 2019. In total, we had 2583 patients. We then excluded all other cancer types except those with a hematological malignancy and 5 other patients due to incomplete data. Results: There were 319 patients with a hematological malignancy. 153 (48%) were female and 166 were male(52%). Most of the patients presented between 30-39 years old (171, 53.6%). There were 54 (2.1%) leukemias and 265 (83.1%) lymphomas. Of those with leukemias, 46 (85.2%) had acute leukemia and 9 (14.8%) had chronic leukemias. Among the lymphoma patients, there were 194 (73.2%) Non Hodgkin Lymphoma (NHL) patients and 69 (26.0%) Hodgkin Lymphoma (HL) patients. There were 149 (46.7%) B Cell lymphomas and 38 (11.9%) T Cell lymphoma patients. The most common B cell Lymphomas is Diffuse Large B Cell Lymphoma (128, 85.9%) and the most common T Cell Lymphomas is Peripheral T-cell Lymphoma (28, 73.7% patients). Conclusions: AYAs with a hematological malignancy form a significant portion of the cancers we see in this age group. Yet, little information is available with regards to their clinico-pathological characteristics, especially in Asia. Work is underway to further elucidate these differences so that we can better their outcomes.


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