scholarly journals Long‐term survivors of childhood, adolescent and young adult non‐Hodgkin lymphoma

2019 ◽  
Vol 185 (6) ◽  
pp. 1099-1110 ◽  
Author(s):  
Matthew J. Ehrhardt ◽  
Jessica Hochberg ◽  
Kari L. Bjornard ◽  
Tara M. Brinkman
Keyword(s):  
Young Adult ◽  
Hodgkin Lymphoma ◽  
Adolescent And Young Adult ◽  
Non Hodgkin Lymphoma ◽  
Long Term Survivors

scholarly journals Childhood, adolescent and young adult non-Hodgkin lymphoma: state of the science

2016 ◽  
Vol 173 (4) ◽  
pp. 503-504 ◽  
Author(s):  
Ross Pinkerton ◽  
Mitchell S. Cairo ◽  
Finbarr E. Cotter
Keyword(s):  
Young Adult ◽  
Hodgkin Lymphoma ◽  
Adolescent And Young Adult ◽  
Non Hodgkin Lymphoma ◽  
State Of The Science

scholarly journals A Retrospective Evaluation of Risk of Peripartum Cardiac Dysfunction in Survivors of Childhood, Adolescent and Young Adult Malignancies

Cancers ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1046
Author(s):  
Chait-Rubinek ◽  
Mariani ◽  
Goroncy ◽  
Herschtal ◽  
Wheeler ◽  
...  
Keyword(s):  
At Risk ◽  
Young Adult ◽  
Cancer Diagnosis ◽  
Cardiac Dysfunction ◽  
Adolescent And Young Adult ◽  
Cardiac Events ◽  
Increased Risk ◽  
Cardiac Assessment ◽  
Long Term Survivors

Long-term survivors of childhood, adolescent and young adult (AYA) malignancies with past exposure to potentially cardiotoxic treatments are at risk of peripartum cardiac dysfunction. Incidence and risk factors for peripartum cardiac dysfunction and maternal cardiac outcomes in this population were investigated. Eligible long-term survivors were aged <30 years at cancer diagnosis, with ≥1 pregnancy occurring ≥5 years after diagnosis. “Peripartum” cardiac events were defined as occurring within pregnancy or ≤5months after delivery. Cardiac events were classified “symptomatic” or “subclinical”. “Peripartum cardiomyopathy” (PPCM) was defined as symptomatic dysfunction without prior cardiac dysfunction. Of 64 eligible women, 5 (7.8%) had peripartum cardiac events: 3 symptomatic, 2 subclinical. Of 110 live births, 2 (1.8%, 95% CI 0.2–6.4) were defined as PPCM: Significantly greater than the published general population incidence of 1:3000 (p < 0.001), representing a 55-fold (95% CI 6.6–192.0) increased risk. Risk factor analyses were hypothesis-generating, revealing younger age at cancer diagnosis and higher anthracycline dose. Postpartum, cardiac function of 4 women (80%) failed to return to baseline. In conclusion, peripartum cardiac dysfunction is an uncommon but potentially serious complication in long-term survivors of paediatric and AYA malignancies previously treated with cardiotoxic therapies. Peripartum cardiac assessment is strongly recommended for at-risk patients.

scholarly journals Childhood, adolescent and young adult non‐Hodgkin lymphoma: current perspectives

2019 ◽  
Vol 185 (6) ◽  
pp. 1021-1042 ◽  
Author(s):  
Mitchell S. Cairo ◽  
Auke Beishuizen
Keyword(s):  
Young Adult ◽  
Hodgkin Lymphoma ◽  
Adolescent And Young Adult ◽  
Non Hodgkin Lymphoma

scholarly journals Quality of Life is Similar between Long-term Survivors of Indolent and Aggressive Non-Hodgkin Lymphoma

2016 ◽  
Vol 34 (6) ◽  
pp. 279-285 ◽  
Author(s):  
Anne W. Beaven ◽  
Greg Samsa ◽  
Sheryl Zimmerman ◽  
Sophia K. Smith
Keyword(s):  
Quality Of Life ◽  
Hodgkin Lymphoma ◽  
Non Hodgkin Lymphoma ◽  
Long Term Survivors

scholarly journals Quality of Life Among Long-Term Survivors of Non-Hodgkin Lymphoma: A Follow-Up Study

2013 ◽  
Vol 31 (2) ◽  
pp. 272-279 ◽  
Author(s):  
Sophia K. Smith ◽  
Deborah K. Mayer ◽  
Sheryl Zimmerman ◽  
Christianna S. Williams ◽  
Habtamu Benecha ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Hodgkin Lymphoma ◽  
Symptom Burden ◽  
Non Hodgkin Lymphoma ◽  
The Impact ◽  
Long Term Survivors ◽  
Over Time

Purpose Little is known about change in quality of life (QOL) among long-term cancer survivors. We examined change over time in QOL among long-term survivors of non-Hodgkin lymphoma and identified demographic, clinical, and psychosocial risk factors for poor outcomes. Methods Surveys were mailed to 682 lymphoma survivors who participated in a study 5 years earlier, when on average they were 10.4 years postdiagnosis. Standardized measures of QOL, perceptions of the impact of cancer, symptoms, medical history, and demographic variables were reported at both time points and examined using linear regression modeling to identify predictors of QOL over time. Results A total of 566 individuals participated (83% response rate) who were a mean of 15.3 years postdiagnosis; 52% were women, and 87% were white. One third of participants (32%) reported persistently high or improved QOL, yet a notable proportion (42%) reported persistently low or worsening QOL since the earlier survey. Participants who received only biologic systemic therapy reported improvement in physical health despite the passage of time. Older age, more comorbidity, and more or increasing negative and decreasing positive perceptions of cancer's impact were independent predictors of poor QOL. Lymphoma symptom burden, less social support, and having received a transplantation were related to negative perceptions of cancer's impact. Conclusion Moderate to severe symptom burden, limited social support, or having received a transplantation should alert the clinician to potential need for supportive services. Perceptions of cancer's impact are associated with QOL cross-sectionally and longitudinally; modifying these perceptions may thus provide a strategy for improving QOL.

Limitations in health care access and utilization among long-term survivors of adolescent and young adult cancer

Cancer ◽  
2012 ◽  
Vol 118 (23) ◽  
pp. 5964-5972 ◽  
Author(s):  
Anne C. Kirchhoff ◽  
Courtney R. Lyles ◽  
Mark Fluchel ◽  
Jennifer Wright ◽  
Wendy Leisenring
Keyword(s):  
Health Care ◽  
Young Adult ◽  
Health Care Access ◽  
Adolescent And Young Adult ◽  
Care Access ◽  
Young Adult Cancer ◽  
Long Term Survivors
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