Porcine Circovirus type 2 – Systemic disease on pig farms and associated knowledge of key players in the pig industry in Central Uganda

The paper deals with the results of assessing the intensity of PCV2 (porcine circovirus type 2) circulation in pigs of different age groups on pig farms in the Russian Federation. Serum samples of 128 pigs of different age groups from two pig farms in the Russian Federation were studied. As a result, specific antibodies to PCV2 were detected that proves virus circulation. Average titer of serum antibodies was 1:2020 for weaning piglets, 40 d.a. (days of age), in prenursery piglets of the age of 20 days - 1:3120; in replacement gilts of the age of 175 days - 1: 5124; in feeding pigs of the age of 180 days - 1:5300. In female pigs, the percentage of seroprevalence was 95 %. With advancing ageing of pigs, the level of antibody titer to PCV2 was increasing that proves the animals were infected after the decrease of colostral antibody level below protective one.

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Torque teno sus virus 1 and 2 distribution in tissues of porcine circovirus type 2-systemic disease affected and age-matched healthy pigs

Veterinary Microbiology ◽

10.1016/j.vetmic.2013.01.005 ◽

2013 ◽

Vol 163 (3-4) ◽

pp. 364-367 ◽

Cited By ~ 15

Author(s):

David Nieto ◽

Tuija Kekarainen ◽

Mario Aramouni ◽

Joaquim Segalés

Keyword(s):

Systemic Disease ◽

Porcine Circovirus Type ◽

Porcine Circovirus Type 2 ◽

Porcine Circovirus ◽

Torque Teno Sus Virus

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Intrahepatic icterus in pigs: rare clinical sign in porcine circovirus type 2 systemic disease

Veterinary Record Case Reports ◽

10.1136/vetreccr-2020-001193 ◽

2020 ◽

Vol 8 (3) ◽

pp. e001193

Author(s):

Robert Graage ◽

Helena Saura Martinez ◽

Stefanie Klausmann ◽

Jakub Kubacki ◽

Dolf Kümmerlen

Keyword(s):

Systemic Disease ◽

In Situ Hybridisation ◽

Porcine Circovirus Type ◽

Porcine Circovirus Type 2 ◽

Porcine Circovirus ◽

Fluorescence In Situ Hybridisation ◽

Tissue Samples ◽

Bilirubin Metabolism ◽

Next Generation Sequencing Ngs

Icterus is a yellow discolouration of tissue and blood plasma due to a disorder of the bilirubin metabolism. This case report describes two porcine circovirus type 2 (PCV2) outbreaks in a fattening farm (F1) and a breeding farm (F2). At F1, pigs had intradermal bleedings and wasting, and three pigs showed icterus. At F2, suckling and weaning pigs (WPs) had an icterus and were wasted. Three fattening pigs (F1), one suckling piglet and one WP (F2) were dissected. Additional investigations included histology, PCV2 immunohistochemistry (IHC), fluorescence in situ hybridisation (FISH) of tissue samples, PCR including sequencing of the PCV2 strains and next-generation sequencing (NGS) of liver samples. Three of the five dissected pigs showed a lymphohistiocytic, periportal hepatitis with disruption of the hepatic cord architecture. PCV2 was detected by IHC, FISH, PCR and NGS in several organs of the pigs. In both farms, sequencing revealed a PCV2b genotype.

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