Amelioration of bleomycin-induced lung fibrosis in rats by valproic acid and butyrate: Role of nuclear factor kappa-B, proinflammatory cytokines and oxidative stress

2016 ◽  
Vol 39 ◽  
pp. 335-342 ◽  
Author(s):  
Ahmed M. Kabel ◽  
Mohamed S. Omar ◽  
Maaly A. Abd Elmaaboud
2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
O. Lorenzo ◽  
B. Picatoste ◽  
S. Ares-Carrasco ◽  
E. Ramírez ◽  
J. Egido ◽  
...  

Diabetic cardiomyopathy entails the cardiac injury induced by diabetes independently of any vascular disease or hypertension. Some transcription factors have been proposed to control the gene program involved in the setting and development of related processes. Nuclear factor-kappa B is a pleiotropic transcription factor associated to the regulation of many heart diseases. However, the nuclear factor-kappa B role in diabetic cardiomyopathy is under investigation. In this paper, we review the nuclear factor-kappa B pathway and its role in several processes that have been linked to diabetic cardiomyopathy, such as oxidative stress, inflammation, endothelial dysfunction, fibrosis, hypertrophy and apoptosis.


2010 ◽  
Vol 114 (3) ◽  
pp. 675-684 ◽  
Author(s):  
María Muriach ◽  
Rosa López-Pedrajas ◽  
Jorge M. Barcia ◽  
María V. Sanchez-Villarejo ◽  
Inmaculada Almansa ◽  
...  

2003 ◽  
Vol 4 (2) ◽  
pp. 121
Author(s):  
K.O. Sung ◽  
F.L. Sung ◽  
K.K.W. Au-Yeung ◽  
J.C.W. Yip ◽  
Y.L. Siow

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