scholarly journals TCT-796: EVEREST II High Surgical Risk Cohort: Clinical Benefit by MR Grade in High Surgical Risk Patients One Year Following MitraClip Therapy

2011 ◽  
Vol 58 (20) ◽  
pp. B212
Keyword(s):  
Clinical Benefit ◽  
Surgical Risk ◽  
High Surgical Risk ◽  
Risk Patients ◽  
One Year ◽  
Mitraclip Therapy

Carotid Stenting with Distal Protection in High-Surgical-Risk Patients: One-Year Results of the ASTI Trial

2014 ◽  
Vol 38 (2) ◽  
pp. 295-303
Author(s):  
Marc Bosiers ◽  
Dierk Scheinert ◽  
Klaus Mathias ◽  
Ralf Langhoff ◽  
Harald Mudra ◽  
...  
Keyword(s):  
Carotid Stenting ◽  
Surgical Risk ◽  
High Surgical Risk ◽  
Risk Patients ◽  
Distal Protection ◽  
One Year

Repeat MitraClip Therapy for Significant Recurrent Mitral Regurgitation in High Surgical Risk Patients

2015 ◽  
Vol 8 (11) ◽  
pp. 1480-1489 ◽  
Author(s):  
Felix Kreidel ◽  
Christian Frerker ◽  
Michael Schlüter ◽  
Hannes Alessandrini ◽  
Thomas Thielsen ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Surgical Risk ◽  
High Surgical Risk ◽  
Risk Patients ◽  
Mitraclip Therapy

FEATURES OF FLUID REDISTRIBUTION DURING GOAL-DIRECTED INFUSION THERAPY OF HIGH SURGICAL RISK PATIENTS IN URGENT SURGERY

2020 ◽  
pp. 29-32
Author(s):  
Olha Viktorivna Kravets
Keyword(s):  
Infusion Therapy ◽  
Volume Depletion ◽  
Surgical Risk ◽  
Mild Degree ◽  
Urgent Surgery ◽  
Post Surgery ◽  
Fluid Redistribution ◽  
High Surgical Risk ◽  
Moderate Volume ◽  
Risk Patients

One of the basic components of intensive treatment of patients with an urgent abdominal pathology is perioperative infusion therapy. To analyze the perioperative dynamics of the water sectors of a body in the patients with a high surgical risk with acute abdominal pathology, a targeted regimen of infusion therapy was used to examine 35 patients. Perioperative targeted infusion therapy was carried out with balanced crystalloid solutions. With the non−invasive bioelectric rheography, the indices of water sectors of a body were studied. On the first day, the extracellular sector volume overflow was established due to an increase in interstitial volume. From the second day, the excess volumes of intravascular fluid and plasma were determined. On the third day there was a deficit of all the studied indices. On the fifth day of the post−surgery period, volumetric depletion of mild degree was noted. From the seventh to the tenth days, all the studied parameters to normal were reliably restored. A targeted regimen of infusion therapy in such patients was concluded to correct a moderate volume depletion on the tenth day after surgery by an excessive increase in plasma volume after six hours of treatment, the development of interstitial edema in the first two days, and the formation of mild volumetric depletion from third to seventh day. Key words: water sectors, goal−direct infusion therapy, depletion, urgent surgery, high surgical risk.

scholarly journals Residual mitral regurgitation impact on outcomes after mitraclip therapy: five-year follow-up from the GRASP registry

2021 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
AM Caggegi ◽  
P Capranzano ◽  
S Scandura ◽  
S Mangiafico ◽  
G Castania ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Repair ◽  
Primary Endpoint ◽  
Left Ventricular ◽  
Valve Repair ◽  
Surgical Risk ◽  
High Surgical Risk ◽  
Mitraclip Therapy

Abstract Funding Acknowledgements Type of funding sources: None. Background – Although percutaneous mitral valve repair is an attractive alternative treatment option for patients with severe mitral regurgitation (MR) at high surgical risk, residual MR is commonly observed after the procedure and little is known about its impact on outcomes after MitraClip therapy, expecially in patients with severe left ventricular (LV) impairment. Purpose – The aim of this prospective, observational study was to evaluate the impact of residual MR (MR ≤1+ vs. MR >1+) on long-term outcomes of mitral valve repair with the MitraClip System in high surgical risk patients presenting with moderate-to-severe or severe MR and with severe reduction of LV ejection fraction (EF). Methods – Patients enrolled in the prospective Getting Reduction of Mitral Insufficiency by Percutaneous Clip Implantation (GRASP) with functional MR and EF ≤30% who were eligible at almost five-year follow-up were included in the present analysis.  The primary endpoint was death at 5-year follow-up.  Also echocardiographic parameters at baseline and 5-year follow-up and rehospitalization rates were assessed. Results – A total of 139 patients were included: 92 (66.2%) with post-procedural residual MR ≤1+ and 47 (33.8%) with residual MR > 1+ (41 patients with residual MR 2+, 5 with residual MR 3+, 1 with residual MR 4+).  Comparable clinical and echocardiographic baseline characteristics were observed between the two groups except for NYHA functional class IV and implanted pace-maker (more frequent in patients with residual MR >1+) and previous myocardial infarction (more frequent  in patients with residual MR ≤1+). At 5-year follow-up, no significant differences were reported in the primary endpoint (49.6% in patients with residual MR ≤ 1+ vs. 65.3% in patients with residual MR > 1+, p 0.203) and in cardiac death (37.8% in patients with residual MR ≤ 1+ vs. 42.6% in patients with residual MR > 1+, p 0.921). Cox regression analysis identified residual MR > 1+ as an independent predictor of re-hospitalization (HR 0.51, 95% CI 0.28-0.92, p =0.026). At 5-year follow-up,  a significant reduction in left ventricular end-systolic volume was  observed in patients with residual MR ≤ 1+. Conclusions – At 5-year follow no significant differences in survival emerged in patients with severe  LV dysfunction undergoing MitraClip therapy regardless residual MR. Nevertheless residual MR > 1+ emerged as an indipendent predictor of re-hospitalization.

scholarly journals CRT-800.22 Combined Simultaneous TAVI And PCI In High Surgical Risk Patients

2017 ◽  
Vol 10 (3) ◽  
pp. S70
Author(s):  
Elena Kovaleva ◽  
David Iosseliani ◽  
Djamil Asadov ◽  
Igor Arabadzhyan ◽  
Irina Isaeva ◽  
...  
Keyword(s):  
Surgical Risk ◽  
High Surgical Risk ◽  
Risk Patients
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