scholarly journals TCT-193 Effect of access site on silent cerebral infarct in patients undergoing coronary angiography and intervention as detected with neuron specific enolase

2017 ◽  
Vol 70 (18) ◽  
pp. B82
Author(s):  
Hüseyin Göksülük ◽  
Sadi Gulec ◽  
Nil Özyüncü ◽  
Seda Kürklü ◽  
Demet Uludağ ◽  
...  
Keyword(s):  
Coronary Angiography ◽  
Neuron Specific Enolase ◽  
Cerebral Infarct ◽  
Access Site ◽  
Silent Cerebral Infarct

scholarly journals Haemorrhagic transformation of a recent silent cerebral infarct during thrombolytic stroke treatment

2008 ◽  
Vol 2008 (nov12 1) ◽  
pp. bcr0620080266-bcr0620080266 ◽  
Author(s):  
K. B. Slot ◽  
E. Berge ◽  
J. Wardlaw
Keyword(s):  
Cerebral Infarct ◽  
Haemorrhagic Transformation ◽  
Stroke Treatment ◽  
Silent Cerebral Infarct

scholarly journals Thrombospondin-1 and L-selectin are associated with silent cerebral infarct in children with sickle cell anaemia

2013 ◽  
Vol 162 (3) ◽  
pp. 421-424 ◽  
Author(s):  
Lisa M. Faulcon ◽  
Zongming Fu ◽  
Pratima Dulloor ◽  
Emily Barron-Casella ◽  
William Savage ◽  
...  
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Anaemia ◽  
Cerebral Infarct ◽  
Thrombospondin 1 ◽  
Silent Cerebral Infarct

scholarly journals Greater Change of Orthostatic Blood Pressure Is Related to Silent Cerebral Infarct and Cardiac Overload in Hypertensive Subjects

2004 ◽  
Vol 27 (4) ◽  
pp. 235-241 ◽  
Author(s):  
Kazuo EGUCHI ◽  
Kazuomi KARIO ◽  
Satoshi HOSHIDE ◽  
Yoko HOSHIDE ◽  
Joji ISHIKAWA ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cerebral Infarct ◽  
Orthostatic Blood Pressure ◽  
Silent Cerebral Infarct

P1706Neurological outcome in patients with out-of-hospital cardiac arrest undergoing a standardised protocol including therapeutic hypothermia and routine coronary angiography

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
M Akin ◽  
V Garcheva ◽  
J T Sieweke ◽  
J Tongers ◽  
L C Napp ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Coronary Angiography ◽  
Therapeutic Hypothermia ◽  
Neurological Outcome ◽  
Life Support ◽  
Neuron Specific Enolase ◽  
Good Neurological Outcome ◽  
Male Predominance ◽  
S 100 ◽  
Hospital Cardiac Arrest

Abstract Purpose To establish cut-offs for neuromarkers such as neuron-specific enolase (NSE) and S-100 predicting good neurological outcome for patients treated with therapeutic hypothermia with out-of-hospital cardiac arrest (OHCA) and return of spontaneous circulation (ROSC) as current cut-offs had been derived from normothermic cohorts. Methods Consecutive data of all patients with OHCA admitted to our institution between 01/2011 and 12/2016 were collected in a database. Patient received standard intensive care according to the Hannover Cardiac Resuscitation Algorithm (HaCRA) including mandatory hypothermia. Neurological markers such as neuron-specific enolase (NSE) and S-100 have been used to assess neurological damage following OHCA. Results Mean age of overall patient population (n=302) was 63±14 [54–74] years with a male predominance (77%). Cardiac arrest was witnessed in 81% and bystander cardiopulmonal resuscitation (CPR) was performed in 67%. Initial rhythm was ventricular fibrillation in 69%. ROSC had been achieved after 24±17 minutes. Hypothermia was applied in all patients. In 95% percutaneous coronary angiography and in 57% of them coronary intervention was performed. After ROSC, STEMI was present in 44%. Mechanical support was required in 19%. 30 day mortality was 44% in the total cohort. Mean NSE was 27±69 μg/l, mean NSE with good neurological outcome was 20±8.7 μg/l, highest NSE with good neurological outcome was 46 μg/l. Mean S-100 was 0.114±2.037μg/l, mean S-100 with good neurological outcome was 0.068±0.067 μg/l, highest S-100 with good neurological outcome was 0.360 μg/l. Conclusion Even when using a strict protocol for OHCA patients and routinely applying therapeutic hypothermia, the cut-offs for NSE and S-100 regarding good neurological outcome are similar to those reported before without therapeutic hypothermia, but they must not be used solitary to withdraw life support as even very high markers can be associated with goof neurological outcome in individual patients.

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