Effects of Conjugated Linoleic Acid (CLA) on HDL-C and Triglyceride levels in Subjects with and without the Metabolic Syndrome: A Systematic Review and Meta-analysis

2019 ◽  
Vol 13 (3) ◽  
pp. e45-e46
Author(s):  
Rossana Maria Calderon Moreno ◽  
Ricardo Correa Marquez ◽  
Anna Oberg ◽  
Stefania Papatheodorou
Keyword(s):  
Systematic Review ◽  
Metabolic Syndrome ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Meta Analysis ◽  
The Metabolic Syndrome

The effects of conjugated linoleic acid (CLA) on metabolic syndrome patients: A systematic review and meta-analysis

2016 ◽  
Vol 25 ◽  
pp. 588-598 ◽  
Author(s):  
Boyeon Kim ◽  
Ha Rae Lim ◽  
Heeyoung Lee ◽  
Hyangki Lee ◽  
Wonku Kang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Metabolic Syndrome ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Meta Analysis

Dairy food consumption is associated with a lower risk of the metabolic syndrome and its components: a systematic review and meta-analysis

2018 ◽  
Vol 120 (4) ◽  
pp. 373-384 ◽  
Author(s):  
Mijin Lee ◽  
Hanna Lee ◽  
Jihye Kim
Keyword(s):  
Systematic Review ◽  
Metabolic Syndrome ◽  
Food Consumption ◽  
Lower Risk ◽  
Meta Analysis ◽  
Cross Sectional ◽  
Dairy Food ◽  
Dairy Foods ◽  
The Metabolic Syndrome ◽  
Cross Sectional Studies

AbstractA systematic review and a meta-analysis of observational studies were performed to assess the dose–response relationship between specific types of dairy foods and the risk of the metabolic syndrome (MetS) and its components. Studies of dairy foods and the risk of the MetS and its components published up to June 2016 were searched using PubMed, EMBASE and a reference search. Random-effects models were used to estimate the pooled relative risks (RR) with 95 % CI. Finally, ten cross-sectional studies, two nested case–control studies and twenty-nine cohort studies were included for the analysis. In a dose–response analysis of cohort studies and cross-sectional studies, the pooled RR of the MetS for a one-serving/d increment of total dairy food (nine studies) and milk (six studies) consumption (200 g/d) were 0·91 (95 % CI 0·85, 0·96) and 0·87 (95 % CI 0·79, 0·95), respectively. The pooled RR of the MetS for yogurt (three studies) consumption (100 g/d) was 0·82 (95 % CI 0·73, 0·91). Total dairy food consumption was associated with lower risk of MetS components, such as hyperglycaemia, elevated blood pressure, hypertriacylglycerolaemia and low HDL- cholesterol. A one-serving/d increment of milk was related to a 12 % lower risk of abdominal obesity, and a one-serving/d increment of yogurt was associated with a 16 % lower risk of hyperglycaemia. These associations were not significantly different by study design, study location or adjustment factors. This meta-analysis showed that specific types of dairy food consumption such as milk and yogurt as well as total dairy food consumption were inversely related to risk of the MetS and its components.

scholarly journals Association of foods enriched in conjugated linoleic acid (CLA) and CLA supplements with lipid profile in human studies: a systematic review and meta-analysis

2014 ◽  
Vol 18 (11) ◽  
pp. 2041-2054 ◽  
Author(s):  
Seyede-Masome Derakhshande-Rishehri ◽  
Marjan Mansourian ◽  
Roya Kelishadi ◽  
Motahar Heidari-Beni
Keyword(s):  
Systematic Review ◽  
Linoleic Acid ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Conjugated Linoleic Acid ◽  
Ldl Cholesterol ◽  
Meta Analysis ◽  
Mean Difference ◽  
Human Studies ◽  
Cochrane Library

AbstractObjectiveThe present study aimed to review the association of conjugated linoleic acid (CLA) consumption in two forms, foods enriched in CLA and CLA supplements, with serum lipid profile in human studies.DesignSystematic review and meta-analysis.SettingSearch process was conducted in PubMed, Cochrane Library, Google Scholar, Scopus and Science Direct. Clinical trials that investigated the association of CLA intakes either in the form of supplements or enriched foods with lipid profile in healthy adults were included. All outcomes were recorded as continuous variables, and the effect size was measured by analysis of the mean and standard deviation before and after the intervention for case and control groups.SubjectsHealthy adult population.ResultsCLA supplementation was associated with a significant decrease in LDL cholesterol (mean difference=−0·218; 95 % CI −0·358, −0·077;P=0·002), a non-significant decrease in HDL cholesterol (mean difference=−0·051; 95 % CI −0·188, 0·086;P=0·468), a non-significant increase in total cholesterol (mean difference=0·009; 95 % CI −0·128, 0·146;P=0·896) and a non-significant decrease in TAG (mean difference=−0·065; 95 % CI −0·20, 0·07;P=0·344). Foods enriched with CLA were associated with significantly decreased LDL cholesterol (mean difference=−0·231; 95 % CI −0·438, −0·024;P=0·028), non-significantly increased HDL-C (mean difference=0·075; 95 % CI −0·121, 0·270;P=0·455), non-significantly decreased total cholesterol (mean difference=−0·158; 95 % CI −0·349, 0·042;P=0·124) and non-significantly decreased TAG (mean difference=−0·078; 95 % CI −0·274, 0·117;P=0·433).ConclusionsAccording to our analysis, consumption of foods enriched with CLA or CLA supplements has favourable effects on LDL cholesterol levels.

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