P1-049: Chronic Memantine administration reduces APP expression, normalizes glutamatergic synapse density, and improves spatial learning in the Ts65Dn mouse model for down syndrome

2008 ◽  
Vol 4 ◽  
pp. T220-T220
Author(s):  
Carmen Martı́nez-Cué ◽  
Noemı́ Rueda ◽  
Marı́a Llorens-Martı́n ◽  
Jesús Flórez ◽  
Elsa Valdizán ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Mouse Model ◽  
Spatial Learning ◽  
Glutamatergic Synapse ◽  
Ts65dn Mouse ◽  
Synapse Density

scholarly journals Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

2013 ◽  
Vol 58 ◽  
pp. 92-101 ◽  
Author(s):  
Ramon Velazquez ◽  
Jessica A. Ash ◽  
Brian E. Powers ◽  
Christy M. Kelley ◽  
Myla Strawderman ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Mouse Model ◽  
Spatial Learning ◽  
Hippocampal Neurogenesis ◽  
Adult Hippocampal Neurogenesis ◽  
Ts65dn Mouse

Memantine Normalizes Several Phenotypic Features in the Ts65Dn Mouse Model of Down Syndrome

2010 ◽  
Vol 21 (1) ◽  
pp. 277-290 ◽  
Author(s):  
Noemí Rueda ◽  
María Llorens-Martín ◽  
Jesús Flórez ◽  
Elsa Valdizán ◽  
Pradeep Banerjee ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Mouse Model ◽  
Ts65dn Mouse ◽  
Phenotypic Features

Hypothermic responses to 8-OH-DPAT in the Ts65Dn mouse model of Down syndrome

Neuroreport ◽  
2006 ◽  
Vol 17 (8) ◽  
pp. 837-841 ◽  
Author(s):  
Melissa R. Stasko ◽  
Jonah J. Scott-McKean ◽  
Alberto C.S. Costa
Keyword(s):  
Down Syndrome ◽  
Mouse Model ◽  
Ts65dn Mouse
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