Perinatal choline supplementation improves spatial learning and increases cholinergic neuron density in the medial septal nucleus in the Ts65Dn mouse model of Down syndrome

2012 ◽  
Vol 34 (3) ◽  
pp. 383
Author(s):  
Ramon Velazquez ◽  
Jessica Ash ◽  
Christy Kelley ◽  
Brian Powers ◽  
Myla Strawderman ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Mouse Model ◽  
Spatial Learning ◽  
Cholinergic Neuron ◽  
Septal Nucleus ◽  
Ts65dn Mouse ◽  
Neuron Density ◽  
Medial Septal Nucleus

P1-049: Chronic Memantine administration reduces APP expression, normalizes glutamatergic synapse density, and improves spatial learning in the Ts65Dn mouse model for down syndrome

2008 ◽  
Vol 4 ◽  
pp. T220-T220
Author(s):  
Carmen Martı́nez-Cué ◽  
Noemı́ Rueda ◽  
Marı́a Llorens-Martı́n ◽  
Jesús Flórez ◽  
Elsa Valdizán ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Mouse Model ◽  
Spatial Learning ◽  
Glutamatergic Synapse ◽  
Ts65dn Mouse ◽  
Synapse Density

scholarly journals Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression in the Ts65Dn Mouse Model of Down Syndrome

2019 ◽  
Vol 79 (7) ◽  
pp. 664-683 ◽  
Author(s):  
Christy M. Kelley ◽  
Stephen D. Ginsberg ◽  
Melissa J. Alldred ◽  
Barbara J. Strupp ◽  
Elliott J. Mufson
Keyword(s):  
Gene Expression ◽  
Down Syndrome ◽  
Mouse Model ◽  
Basal Forebrain ◽  
Cholinergic Neuron ◽  
Ts65dn Mouse ◽  
Basal Forebrain Cholinergic Neuron

scholarly journals Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

2013 ◽  
Vol 58 ◽  
pp. 92-101 ◽  
Author(s):  
Ramon Velazquez ◽  
Jessica A. Ash ◽  
Brian E. Powers ◽  
Christy M. Kelley ◽  
Myla Strawderman ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Mouse Model ◽  
Spatial Learning ◽  
Hippocampal Neurogenesis ◽  
Adult Hippocampal Neurogenesis ◽  
Ts65dn Mouse

scholarly journals Attentional function and basal forebrain cholinergic neuron morphology during aging in the Ts65Dn mouse model of Down syndrome

2015 ◽  
Vol 221 (9) ◽  
pp. 4337-4352 ◽  
Author(s):  
Brian E. Powers ◽  
Ramon Velazquez ◽  
Christy M. Kelley ◽  
Jessica A. Ash ◽  
Myla S. Strawderman ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Mouse Model ◽  
Basal Forebrain ◽  
Cholinergic Neuron ◽  
Ts65dn Mouse ◽  
Neuron Morphology ◽  
Attentional Function ◽  
Basal Forebrain Cholinergic Neuron

Memantine Normalizes Several Phenotypic Features in the Ts65Dn Mouse Model of Down Syndrome

2010 ◽  
Vol 21 (1) ◽  
pp. 277-290 ◽  
Author(s):  
Noemí Rueda ◽  
María Llorens-Martín ◽  
Jesús Flórez ◽  
Elsa Valdizán ◽  
Pradeep Banerjee ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Mouse Model ◽  
Ts65dn Mouse ◽  
Phenotypic Features
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