[P1-104]: DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL BENZYLAMINE DERIVATIVES WITH HYDROXYETHYLAMINE PHARMACOPHORIC MOIETY AS MULTIFUNCTIONAL COMPOUNDS TARGETING CHOLINESTERASE, BETA-SECRETASE AND BETA-AMYLOID AGGREGATION

Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2012.10.003 ◽

2012 ◽

Vol 58 ◽

pp. 84-97 ◽

Cited By ~ 25

Author(s):

Marco Catto ◽

Andrey A. Berezin ◽

Daniele Lo Re ◽

Georgia Loizou ◽

Marina Demetriades ◽

...

Keyword(s):

Beta Amyloid ◽

Biological Evaluation ◽

Amyloid Aggregation ◽

Design Synthesis ◽

Dual Inhibitors ◽

Butyryl Cholinesterase ◽

Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.09.078 ◽

2017 ◽

Vol 125 ◽

pp. 676-695 ◽

Cited By ~ 60

Author(s):

Dawid Panek ◽

Anna Więckowska ◽

Tomasz Wichur ◽

Marek Bajda ◽

Justyna Godyń ◽

...

Keyword(s):

Amyloid Beta ◽

Biological Evaluation ◽

Design Synthesis ◽

Beta Secretase ◽

Design, synthesis and biological evaluation of indane-2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as β-amyloid aggregation inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2009.12.029 ◽

2010 ◽

Vol 45 (4) ◽

pp. 1359-1366 ◽

Cited By ~ 26

Author(s):

Marco Catto ◽

Rosaria Aliano ◽

Angelo Carotti ◽

Saverio Cellamare ◽

Fausta Palluotto ◽

...

Keyword(s):

Biological Evaluation ◽

Amyloid Aggregation ◽

Design Synthesis ◽

Aggregation Inhibitors ◽

Β Amyloid ◽

Design, synthesis, and biological evaluation of 4‐aminopyrimidine or 4,6‐diaminopyrimidine derivatives as beta amyloid cleaving enzyme‐1 inhibitors

Chemical Biology & Drug Design ◽

10.1111/cbdd.13489 ◽

2019 ◽

Vol 93 (5) ◽

pp. 926-933 ◽

Cited By ~ 2

Author(s):

Xiufeng Xu ◽

Peng Lü ◽

Junjie Wang ◽

Fengrong Xu ◽

Lei Liang ◽

...

Keyword(s):

Beta Amyloid ◽

Biological Evaluation ◽

Design Synthesis ◽

Design, Synthesis and Biological Evaluation of some Chalcone Derivatives as Potential Pancreatic Lipase Inhibitors

10.3390/ecsoc-17-b024 ◽

2013 ◽

Author(s):

Dao Tran

Keyword(s):

Pancreatic Lipase ◽

Biological Evaluation ◽

Design Synthesis ◽

Chalcone Derivatives ◽

Pancreatic Lipase Inhibitors ◽

Faculty Opinions recommendation of Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726271231.793520213 ◽

2016 ◽

Author(s):

Miles Congreve ◽

Mark Pickworth

Keyword(s):

G Protein ◽

Biological Evaluation ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

Design Synthesis ◽

G Protein Coupled ◽

Design, Synthesis and Biological Evaluation of Hybrid Molecules Containing Conjugated Styryl Ketone and α-Bromoacryloyl Moieties

10.2174/157018012799079842 ◽

2012 ◽

Vol 9 (2) ◽

pp. 140-152 ◽

Cited By ~ 1

Author(s):

Romeo Romagnoli ◽

Pier Giovanni Baraldi ◽

Olga Cruz-Lopez ◽

Maria Kimatrai Salvador ◽

Delia Preti ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Hybrid Molecules ◽

Design, Synthesis and Biological Evaluation of Novel Aminosaccharide Derivatives of Combretastatin A-4

10.2174/15701808113109990024 ◽

2013 ◽

Vol 10 (10) ◽

pp. 935-941

Author(s):

Yan Tang ◽

Zhewei Tu ◽

Jing Sun ◽

Xiong Zhu ◽

Kun Liu ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Derivatives Of

Design, Synthesis and Biological Evaluation of Some Oxadiazole Derivatives as Novel Amide-Based Inhibitors of Soluble Epoxide Hydrolase

10.2174/1570180811666140220005530 ◽

2014 ◽

Vol 11 (6) ◽

pp. 721-730 ◽

Cited By ~ 8

Author(s):

Elham Zavareh ◽

Mahdi Hedayati ◽

Laleh Rad ◽

Azin Kiani ◽

Soraya Shahhosseini ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Soluble Epoxide Hydrolase ◽

Biological Evaluation ◽

Design Synthesis ◽

Oxadiazole Derivatives ◽

Rational Design, Synthesis and Biological Evaluation of Novel Derivatives Based on in vivo Metabolism of Natural Product β-elemene

10.2174/1570180814666171108093021 ◽

2018 ◽

Vol 15 (8) ◽

pp. 905-912 ◽

Cited By ~ 1

Author(s):

Renren Bai ◽

Xiaokang Jie ◽

Eric Salgado ◽

Jian Sun ◽

Yao Zhu ◽

...

Keyword(s):

Natural Product ◽

Rational Design ◽

Biological Evaluation ◽

In Vivo Metabolism ◽

Design Synthesis ◽