Valproic acid increases endothelial glycocalyx shedding and decreases lesion size volume in a rodent model of severe isolated traumatic brain injury

2013 ◽  
Vol 217 (3) ◽  
pp. S32 ◽  
Author(s):  
Cecilie H. Jepsen ◽  
Pär I. Johansson ◽  
Anders Perner ◽  
Martin H. Sillesen ◽  
Hasan B. Alam ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Brain Injury ◽  
Lesion Size ◽  
Rodent Model ◽  
Endothelial Glycocalyx

Effect of valproic acid and injury on lesion size and endothelial glycocalyx shedding in a rodent model of isolated traumatic brain injury

2014 ◽  
Vol 77 (2) ◽  
pp. 292-297 ◽  
Author(s):  
Cecilie Heerdegen Jepsen ◽  
Marc A. deMoya ◽  
Anders Perner ◽  
Martin Sillesen ◽  
Sisse R. Ostrowski ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Brain Injury ◽  
Lesion Size ◽  
Rodent Model ◽  
Endothelial Glycocalyx

A Single Dose of Valproic Acid Improves Neurologic Recovery and Decreases Brain Lesion Size in Swine Subjected to an Isolated Traumatic Brain Injury

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Glenn K. Wakam ◽  
Ben E. Biesterveld ◽  
Manjunath P. Pai ◽  
Michael T. Kemp ◽  
Rachel L. O’Connell ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Single Dose ◽  
Brain Injury ◽  
Brain Lesion ◽  
Lesion Size ◽  
Neurologic Recovery

Valproic acid decreases brain lesion size and improves neurologic recovery in swine subjected to traumatic brain injury, hemorrhagic shock, and polytrauma

2017 ◽  
Vol 83 (6) ◽  
pp. 1066-1073 ◽  
Author(s):  
Vahagn C. Nikolian ◽  
Patrick E. Georgoff ◽  
Manjunath P. Pai ◽  
Isabel S. Dennahy ◽  
Kiril Chtraklin ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Brain Injury ◽  
Hemorrhagic Shock ◽  
Brain Lesion ◽  
Lesion Size ◽  
Neurologic Recovery

Study of neurometabolic and behavioral alterations in rodent model of mild traumatic brain injury: a pilot study

2016 ◽  
Vol 29 (12) ◽  
pp. 1748-1758 ◽  
Author(s):  
Kavita Singh ◽  
Richa Trivedi ◽  
Seenu Haridas ◽  
Kailash Manda ◽  
Subash Khushu
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Pilot Study ◽  
Mild Traumatic Brain Injury ◽  
Rodent Model ◽  
Behavioral Alterations

A receptor-binding radiopharmaceutical for imaging of traumatic brain injury in a rodent model: [99mTc]Tc-tilmanocept

2020 ◽  
Author(s):  
Wen Chen ◽  
Christopher V. Barback ◽  
Shanshan Wang ◽  
Carl K. Hoh ◽  
Eric Y. Chang ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Receptor Binding ◽  
Rodent Model

Valproic Acid Induces the NEUROD1 Transcriptional Program of Neurogenesis after Traumatic Brain Injury

2016 ◽  
Vol 223 (4) ◽  
pp. S160 ◽  
Author(s):  
Patrick E. Georgoff ◽  
Gerald Higgins ◽  
Vahagn C. Nikolian ◽  
Ted Bambakidis ◽  
Simone E. Dekker ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Brain Injury ◽  
Transcriptional Program
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