Comparing High Dose vs. Standard Dose Influenza Vaccine Efficacy in Flu Prevention within the Elderly Population in Acute Care and Long-Term Care

2016 ◽  
Vol 17 (3) ◽  
pp. B24-B25
Author(s):  
Sara Fearn ◽  
Sara Fearn ◽  
Jennifer Forsyth ◽  
Crystal Jones
Keyword(s):  
Influenza Vaccine ◽  
Acute Care ◽  
Vaccine Efficacy ◽  
Elderly Population ◽  
Long Term Care ◽  
Standard Dose ◽  
The Elderly ◽  
High Dose ◽  
Term Care

Cost Benefit of High-Dose vs Standard-Dose Influenza Vaccine in a Long-Term Care Population During an A/H1N1-Predominant Influenza Season

2019 ◽  
Vol 20 (7) ◽  
pp. 874-878 ◽  
Author(s):  
Theresa I. Shireman ◽  
Jessica Ogarek ◽  
Pedro Gozalo ◽  
Tingting Zhang ◽  
Vincent Mor ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Long Term Care ◽  
Influenza Season ◽  
Standard Dose ◽  
Cost Benefit ◽  
High Dose ◽  
Term Care

scholarly journals Correlates of Protection against Influenza in the Elderly: Results from an Influenza Vaccine Efficacy Trial

2016 ◽  
Vol 23 (3) ◽  
pp. 228-235 ◽  
Author(s):  
Andrew J. Dunning ◽  
Carlos A. DiazGranados ◽  
Timothy Voloshen ◽  
Branda Hu ◽  
Victoria A. Landolfi ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Vaccine Efficacy ◽  
Standard Dose ◽  
The Elderly ◽  
High Dose ◽  
Efficacy Trial ◽  
Correlates Of Protection ◽  
Immune Correlates ◽  
Immunologic Assays ◽  
Dose Vaccine

ABSTRACTAlthough a number of studies have investigated and quantified immune correlates of protection against influenza in adults and children, data on immune protection in the elderly are sparse. A recent vaccine efficacy trial comparing standard-dose with high-dose inactivated influenza vaccine in persons 65 years of age and older provided the opportunity to examine the relationship between values of three immunologic assays and protection against community-acquired A/H3N2 influenza illness. The high-dose vaccine induced significantly higher antibody titers than the standard-dose vaccine for all assays. For the hemagglutination inhibition assay, a titer of 40 was found to correspond with 50% protection when the assay virus was antigenically well matched to the circulating virus—the same titer as is generally recognized for 50% protection in younger adults. A dramatically higher titer was required for 50% protection when the assay virus was a poor match to the circulating virus. With the well-matched virus, some protection was seen at the lowest titers; with the poorly matched virus, high levels of protection were not achieved even at the highest titers. Strong associations were also seen between virus neutralization test titers and protection, but reliable estimates for 50% protection were not obtained. An association was seen between titers of an enzyme-linked lectin assay for antineuraminidase N2 antibodies and protection; in particular, the proportion of treatment effect explained by assay titer in models that included both this assay and one of the other assays was consistently higher than in models that included either assay alone. (This study has been registered at ClinicalTrials.gov under registration no. NCT01427309.)

The Graying of America: Implications for Health Professionals

2005 ◽  
Vol 6 (4) ◽  
pp. 178-184 ◽  
Author(s):  
James D. Wright
Keyword(s):  
Health Care ◽  
Health Care System ◽  
Health Professionals ◽  
Elderly Population ◽  
Long Term Care ◽  
The Elderly ◽  
Term Care ◽  
Demographic Projections ◽  
Care Industry

Demographic projections confirm a dramatic increase in the size of America’s elderly population over the next several decades. The elderly now comprise 13% of the population; by 2045, they will comprise 22%. As the elderly population grows, so too will the elderly poor, the elderly homeless, and the elderly uninsured. The implications of the so-called graying of America for the health care system, particularly the long-term care industry, are staggering.

scholarly journals The Subtle and Silent Issue in Older Adult Care

2021 ◽  
Vol 11 (S1) ◽  
Author(s):  
Sarah Fu
Keyword(s):  
Older Adult ◽  
Elderly Population ◽  
Long Term Care ◽  
The Elderly ◽  
Care Homes ◽  
Medical Community ◽  
Adult Care ◽  
Term Care ◽  
Poor Treatment

The treatment of elders in the community and ageism in our society has been an issue often underlooked. However, since the onset of the COVID-19 pandemic, poor treatment of elders in the community and long term care homes has been brought to light. During the beginning of the pandemic, long term care homes in Canada accounted for around 80% of all COVID-19 related mortalities [1]. This situation is due to an amalgamation of factors leading towards the ultimate neglect of the elderly population, including the governance of long term care homes in Canada, the stigma against the elderly population, and the commonly misconceived clinical picture of a ‘frail’ senior by the medical community.

Sexuality and sexual dysfunctions in older people: a forgotten problem

2020 ◽  
Vol 26 (3) ◽  
pp. 173-182
Author(s):  
Philip Slack ◽  
Victor M. Aziz
Keyword(s):  
Sexual Functioning ◽  
Elderly Population ◽  
Long Term Care ◽  
The Elderly ◽  
Sexual Dysfunctions ◽  
Physiological Changes ◽  
Term Care ◽  
Sexual Side Effects ◽  
Sexual Disinhibition

SUMMARYThis article considers sexuality in older adults and the associated stereotypes and stigmas that lead to this area being underappreciated. Normal physiological changes in ageing are discussed and how they can cause sexual dysfunction. The elderly population has a higher burden of comorbid physical illness and this review considers evidence on the interplay between physical health and sexual health. Mental illness is also strongly linked with sexual functioning and is discussed, as is the evidence on psychotropics and sexual side-effects. Attitudes on sexuality in long-term care settings are highlighted and approaches to managing sexual disinhibition are included.

scholarly journals Improving Prediction of Risk of Admission to Long-Term Care or Mortality Among Home Care Users With IDD

2018 ◽  
Vol 21 (4) ◽  
pp. 303-306
Author(s):  
Hélène Ouellette-Kuntz ◽  
Elizabeth Stankiewicz ◽  
Michael McIsaac ◽  
Lynn Martin
Keyword(s):  
Home Care ◽  
Elderly Population ◽  
Long Term Care ◽  
Frailty Index ◽  
The Elderly ◽  
Assessment Instrument ◽  
P Value ◽  
Term Care ◽  
Age Related

BackgroundFrailty is an established predictor of admission into long-term care (LTC) and mortality in the elderly population. Assessment of frailty among adults with intellectual and developmental disabilities (IDD) using a generic frailty marker may not be as predictive, as some lifelong disabilities associated with IDD may be interpreted as a sign of frailty. This study set out to determine if adding the Home Care-Intellectual and Devel-opmental Disabilities Frailty Index (HC-IDD Frailty Index), developed for use in home care users with IDD, to a basic list of predictors (age, sex, rural status, and the Johns Hopkins Frailty Marker) increases the ability to predict admission to long-term care or death within one year.MethodsA retrospective cohort study was conducted using Residential Assessment Instrument for Home Care (RAI-HC) data for adult home care users with IDD who had a home care as-sessment between January 1, 2010 and December 31, 2013 (N = 6,169).ResultsThe HC-IDD Frailty Index was found to significantly improve prediction of transitions into LTC or death by explaining an additional 5.95% of the variance in such transitions among home care users with IDD (p value < .0001).ConclusionsWe recommend the use of the HC-IDD Frailty Index in care planning and in further research related to the effectiveness of interventions to reduce or delay adverse age-related outcomes among adults with IDD.

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