Associations among Muscle Mass, Hand Grip Strength, and Nutritional Risk by the Comprehensive Older Adult Screening Tool (COAST) in Community-Dwelling Older Adults

This study examined the effects of a person-centered nursing intervention program for frailty (PNIF) targeting community-dwelling prefrail older people in South Korea. The study participants were 40 community-dwelling older adults (≥65 years) who were classified as prefrail on the Cardiovascular Health Study (CHS) frailty index. The intervention group (n = 20) received group intervention sessions two days/week for twelve weeks and the control group (n = 20) attended lectures about frailty prevention one day/week for four weeks. The evaluation instruments included the CHS Frailty Index, a JAMAR® hydraulic hand dynamometer, the Short Physical Performance Battery (SPPB), the Korean version of the Community Healthy Activities Model Program for Seniors Questionnaire (K-CHAMPS), the Mini Nutritional Assessment (MNA), the Geriatric Depression Scale Short Form-Korea Version (GDSSF-K), the ENRICHD Social Support Instrument (ESSI), and the Goal Attainment Scale (GAS). Significant differences were found in the CHS Frailty Index (p < 0.001), left-hand grip strength (p = 0.022), right-hand grip strength (p = 0.009), SPPB (p = 0.007), K-CHAMPS (p = 0.009), MNA (p = 0.018), and GDSSF-K (p = 0.001) between the two groups after 12 weeks. No significant between-group differences in ESSI scores were observed. The PNIF effectively improved grip strength, physical function, physical activity, and nutritional status, reduced depression, and prevented frailty among community-dwelling older adults.

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NOVEL METABOLOMICS MARKERS PREDICT 18-MONTH DECLINE IN HAND GRIP STRENGTH IN COMMUNITY-DWELLING OLDER ADULTS

Innovation in Aging ◽

10.1093/geroni/igz038.216 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

pp. S56-S56

Author(s):

Ted Kheng Siang Ng ◽

Jean-Paul Kovalik ◽

Jianhong Ching ◽

Angelique Chan ◽

David Matchar

Keyword(s):

Older Adults ◽

Grip Strength ◽

Hand Grip Strength ◽

Community Dwelling ◽

Inverse Association ◽

Metabolic Markers ◽

Biologically Relevant ◽

Fuel Metabolism ◽

Hand Grip ◽

Community Dwelling Older Adults

Abstract Sarcopenia that accompanies aging necessitates early detection tools, ideally before the presentation of clinically evident symptoms. The acylcarnitines (ACs) are a class of metabolites generated by cellular fuel metabolism and their predictive utility in declining muscle strength in community-dwelling older adults is unknown. We aim to examine whether baseline acylcarnitines levels can predict changes in hand grip strength over 18 months in 121 community-dwelling older adults. We measured ACs by targeted plasma metabolomics profiling. We then performed a biologically-relevant classification of these markers. Hand grip strength was measured using a Smedley spring-type dynamometer. Multivariate linear regressions were performed to examine if: 1) there was an association between ACs and hand grip strength at baseline and 2) baseline ACs could significantly predict changes in hand grip strength over an 18-month period. At baseline, AC levels were not significantly associated with hand grip strength. We found an inverse association between baseline short-chain carboxyl and dihydroxl acylcarnitines (AC-DC/-OH) levels and 18-month changes in hand grip strength (p=0.047, β=-0.548, 95% CI=-1.088 to -0.008). Notably, a specific AC-DC/-OH species, C4-DC/C6-OH, accounts for the majority of the variance. The mean difference between Malay and Chinese ethnicity is 2.28kg (p=0.042, β=2.275, 95% CI=0.084 to 4.466). These findings suggest an association between metabolic markers and deterioration in hand grip strength. These results suggest that perturbations in fuel metabolism are detectable way before the emergence of clinically evident sarcopenia and frailty. The use of AC-DC/-OH panel as antecedent biomarkers may enable clinicians to risk stratify patients in the future.

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DISCRIMINATION OF MOBILITY LIMITATION BY HAND-GRIP STRENGTH AMONG COMMUNITY-DWELLING OLDER ADULTS

Japanese Journal of Physical Fitness and Sports Medicine ◽

10.7600/jspfsm.60.259 ◽

2011 ◽

Vol 60 (3) ◽

pp. 259-268 ◽

Cited By ~ 6

Author(s):

SATOSHI SEINO ◽

MI-JI KIM ◽

NORIKO YABUSHITA ◽

TOMOAKI MATSUO ◽

SONGEE JUNG ◽

...

Keyword(s):

Older Adults ◽

Grip Strength ◽

Hand Grip Strength ◽

Community Dwelling ◽

Mobility Limitation ◽

Hand Grip ◽

Community Dwelling Older Adults

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BODY COMPOSITION AND HAND GRIP STRENGTH IN HEALTHY COMMUNITY-DWELLING OLDER ADULTS IN SWEDEN

Journal of Aging Research and Lifestyle ◽

10.14283/jarcp.2015.50 ◽

2015 ◽

pp. 1-5

Author(s):

A. Lindblad ◽

S. Dahlin-Ivanoff ◽

I. Bosaeus ◽

E. Rothenberg

Keyword(s):

Body Composition ◽

Muscle Strength ◽

Grip Strength ◽

Muscle Mass ◽

Hand Grip Strength ◽

Community Dwelling ◽

Consensus Definition ◽

Hand Grip ◽

European Consensus ◽

Community Dwelling Older Adults

Background: Longevity increases worldwide but there are few studies on body composition and hand grip strength in populations over 80 years. Given high prevalence of chronic disease and functional disability in octogenarians, it may be difficult to distinguish effects of ageing from those imposed by disease. The European Consensus definition of sarcopenia recommends using both low muscle mass and function for diagnosis. Objectives: Examine body composition and hand grip strength in a selected group of community-dwelling older adults with high level of functional independence. In addition, longitudinal changes in handgrip strength were examined using previously collected data. Design: Cross-sectional body composition and hand grip strength with a four year retrospective analysis on previously assessed hand grip strength. Setting: Measurements were conducted by home visits. Participants: 102 community-dwelling 83-96 year-olds, 50 % women. Measurements: Hand grip strength was registered by a dynamometer and body composition analysis using bioimpedance spectroscopy. Results: According to European Consensus definition, only 6/102 had normal muscle mass - no men, although 78 % of men and 40 % of women had normal muscle strength. Since previously collected data four years earlier, men had lost strength (p<0.001), while women had not (p=0.202). Conclusions: Subject characteristics and health status support well-preserved body energy, protein stores and muscle strength. Low muscle mass was much more prevalent than low muscle strength. Results may give an indication of what constitutes a healthy body composition in oldest old and could serve as a starting point for reference values on healthy body composition in octogenarians.

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