scholarly journals Conjugation of haloperidol to PEG allows peripheral localisation of haloperidol and eliminates CNS extrapyramidal effects

2020 ◽  
Vol 322 ◽  
pp. 227-235
Author(s):  
Az Alddien Natfji ◽  
Dmitry O. Nikitin ◽  
Irina I. Semina ◽  
Rouslan I. Moustafine ◽  
Vitaliy V. Khutoryanskiy ◽  
...  
Keyword(s):  
Extrapyramidal Effects

scholarly journals Extrapyramidal effects of neuroleptics.

1976 ◽  
Vol 39 (9) ◽  
pp. 866-869 ◽  
Author(s):  
A D Korczyn ◽  
G J Goldberg
Keyword(s):  
Extrapyramidal Effects

Comparative extrapyramidal effects of Rauwolfia vomitoria, chlorpromazine and reserpine in mice

2012 ◽  
Vol 67 (1) ◽  
pp. 107-112 ◽  
Author(s):  
Sunday Agba Bisong ◽  
Richard Earl Brown ◽  
Eme Effiom Osim
Keyword(s):  
Extrapyramidal Effects ◽  
Rauwolfia Vomitoria

Treatment of Phenothiazine Overdosage With Physostigmine

PEDIATRICS ◽  
1977 ◽  
Vol 59 (2) ◽  
pp. 301-303
Author(s):  
Stephen F. Wang ◽  
Christopher L. Marlowe
Keyword(s):  
Central Nervous System ◽  
Hypersensitivity Reactions ◽  
Accidental Ingestion ◽  
Small Children ◽  
Psychiatric Illnesses ◽  
Symptomatic Medication ◽  
The Central Nervous System ◽  
Extrapyramidal Effects ◽  
Medicine Today ◽  
Cns Depression

Phenothiazines are among the most widely used drugs in medicine today.1 They are used principally for the treatment of psychiatric illnesses and as symptomatic medication for nausea and vomiting. Most articles in the pediatric literature have dealt with the extrapyramidal effects of phenothiazine toxicity which are successfully treated with antihistamines.2,3 In a review of phenothiazine toxicity in children these were the major side effects mentioned.4 Phenothiazines can also produce the dangerous hypersensitivity reactions of agranulocytosis, hepatitis, and dermatitis.1 Overdosage, usually due to accidental ingestion in small children, can cause changes at all levels of the central nervous system. CNS depression has been manifested after ingestion of 100 mg by children 5 years of age and younger5; a 1-year-old child became comatose and apneic after swallowing 200 mg of chlorpromazine,5 and a 3-year-old died after ingestion of 800 mg.6

Acute Lithium-Induced Tremor

1983 ◽  
Vol 143 (1) ◽  
pp. 40-41 ◽  
Author(s):  
S. Pullinger ◽  
P. Tyrer
Keyword(s):  
Drug Treatment ◽  
Antipsychotic Drugs ◽  
Signs And Symptoms ◽  
Lithium Therapy ◽  
Physiological Tremor ◽  
Antiparkinsonian Drug ◽  
Extrapyramidal Signs ◽  
Extrapyramidal Effects ◽  
Acute Lithium

It has recently been found that tremor in patients on long-term lithium therapy has a lower frequency than that of normal physiological tremor and is likely to have an extrapyramidal component (Tyrer et al, 1981). Other extrapyramidal signs and symptoms have been found with chronic lithium therapy (Shopsin and Gershon, 1975; Baastrup et al, 1976; Branchey et al, 1976; Asnis et al, 1979). These extrapyramidal effects differ from the pseudoparkinsonism produced by antipsychotic drugs in that they do not respond to antiparkinsonian drug treatment (Schou, 1970; Tyrer et al, 1980).

A Mutual Prodrug Ester of GABA and Perphenazine Exhibits Antischizophrenic Efficacy with Diminished Extrapyramidal Effects

2008 ◽  
Vol 51 (9) ◽  
pp. 2858-2862 ◽  
Author(s):  
Abraham Nudelman ◽  
Irit Gil-Ad ◽  
Nava Shpaisman ◽  
Igor Terasenko ◽  
Hanna Ron ◽  
...  
Keyword(s):  
Extrapyramidal Effects ◽  
Mutual Prodrug

EXTRAPYRAMIDAL EFFECTS OF TRANQUILLISERS

The Lancet ◽  
1962 ◽  
Vol 279 (7222) ◽  
pp. 221-222 ◽  
Author(s):  
S. Shafer ◽  
L. Joseph ◽  
J.P. Anderson
Keyword(s):  
Extrapyramidal Effects

Extrapyramidal effects of acute organophosphate poisoning

2016 ◽  
Vol 54 (3) ◽  
pp. 259-265 ◽  
Author(s):  
Kent K. Reji ◽  
Vivek Mathew ◽  
Anand Zachariah ◽  
Anil Kumar B. Patil ◽  
Samuel George Hansdak ◽  
...  
Keyword(s):  
Organophosphate Poisoning ◽  
Extrapyramidal Effects
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