Influence of severity of nuclear cataract on optical biometry

2006 ◽  
Vol 32 (7) ◽  
pp. 1161-1165 ◽  
Author(s):  
Ana Prinz ◽  
Thomas Neumayer ◽  
Wolf Buehl ◽  
Barbara Kiss ◽  
Stefan Sacu ◽  
...  
Keyword(s):  
Nuclear Cataract ◽  
Optical Biometry

scholarly journals COMPARISON OF OPTICAL BIOMETRY AND A SCAN FOR CALCULATION OF INTRAOCULAR LENS POWER IN AGE RELATED NUCLEAR CATARACT AT TERTIARY CARE EYE HOSPITAL

2021 ◽  
Vol 71 (5) ◽  
pp. 1828-32
Author(s):  
Aisha Rafique ◽  
Omar Zafar ◽  
Summaya Khan
Keyword(s):  
Intraocular Lens ◽  
Tertiary Care ◽  
Military Hospital ◽  
P Value ◽  
Power Calculation ◽  
Nuclear Cataract ◽  
Optical Biometry ◽  
Age Related ◽  
Intraocular Lens Power ◽  
Lens Power

Objective: To compare optical biometry and A-scan for calculating intraocular lens power in patients with nuclear cataract at tertiary care eye hospital. Study Design: Cross sectional comparative study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Pak Emirates Military Hospital, Rawalpindi, from Jul to Dec 2018. Methodology: In this study 70 eyes of 70 patients planned for cataract surgery by phacoemulsification underwent both optical biometry with intraocular lens master and ultrasound biometry applanation by A scan after informed consent. Intraocular lens power calculated by these two methods of biometry was compared. Phacoemulsification surgery was performed through a 2.3 mm superior temporal clear corneal incision. All patients underwent in the bag implantation of the same intraocular lens type. Results: The mean age of the patients was 62.89 ± 6.69 years. A significant (p-value<0.001) difference in intraocular lens power calculation was noted (20.96 ± 1.76 vs. 22.03 ± 1.61) with optical biometry and A-scan respectively. Association on the basis of age groups showed a significant (p-value<0.001) difference in both strata that was among patients having age ≤65 years and patients having age >65 years. Conclusion: Optical biometry was found efficient and safe method for calculation of intraocular lens power. Optical biometry is noncontact method having very less chance of infection and suitable for most of the eye types.

Pathogenesis of Age-related Cataract: a systematic review of proteomic studies

2020 ◽  
Vol 17 ◽  
Author(s):  
Christina Karakosta ◽  
Argyrios Tzamalis ◽  
Michalis Aivaliotis ◽  
Ioannis Tsinopoulos
Keyword(s):  
Systematic Review ◽  
Oxidant Stress ◽  
Critical Role ◽  
Human Lens ◽  
Nuclear Cataract ◽  
Cataract Formation ◽  
Post Translational Modification ◽  
Ability To Act ◽  
Age Related

Background/Objective:: The aim of this systematic review is to identify all the available data on human lens proteomics with a critical role to age-related cataract formation in order to elucidate the physiopathology of the aging lens. Materials and Methods:: We searched on Medline and Cochrane databases. The search generated 328 manuscripts. We included nine original proteomic studies that investigated human cataractous lenses. Results:: Deamidation was the major age-related post-translational modification. There was a significant increase in the amount of αA-crystallin D-isoAsp58 present at all ages, while an increase in the extent of Trp oxidation was apparent in cataract lenses when compared to aged normal lenses. During aging, enzymes with oxidized cysteine at critical sites included GAPDH, glutathione synthase, aldehyde dehydrogenase, sorbitol dehydrogenase, and PARK7. Conclusion:: D-isoAsp in αA crystallin could be associated with the development of age-related cataract in human, by contributing to the denaturation of a crystallin, and decreasing its ability to act as a chaperone. Oxidation of Trp may be associated with nuclear cataract formation in human, while the role of oxidant stress in age-related cataract formation is dominant.

scholarly journals Gender differences in refraction prediction error of five formulas for cataract surgery

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yibing Zhang ◽  
Tingyang Li ◽  
Aparna Reddy ◽  
Nambi Nallasamy
Keyword(s):  
Gender Differences ◽  
Cataract Surgery ◽  
Prediction Error ◽  
Statistical Difference ◽  
Independent Predictor ◽  
Study Data ◽  
Prediction Errors ◽  
Optical Biometry ◽  
Iol Power ◽  
Lens Power

Abstract Objectives To evaluate gender differences in optical biometry measurements and lens power calculations. Methods Eight thousand four hundred thirty-one eyes of five thousand five hundred nineteen patients who underwent cataract surgery at University of Michigan’s Kellogg Eye Center were included in this retrospective study. Data including age, gender, optical biometry, postoperative refraction, implanted intraocular lens (IOL) power, and IOL formula refraction predictions were gathered and/or calculated utilizing the Sight Outcomes Research Collaborative (SOURCE) database and analyzed. Results There was a statistical difference between every optical biometry measure between genders. Despite lens constant optimization, mean signed prediction errors (SPEs) of modern IOL formulas differed significantly between genders, with predictions skewed more hyperopic for males and myopic for females for all 5 of the modern IOL formulas tested. Optimization of lens constants by gender significantly decreased prediction error for 2 of the 5 modern IOL formulas tested. Conclusions Gender was found to be an independent predictor of refraction prediction error for all 5 formulas studied. Optimization of lens constants by gender can decrease refraction prediction error for certain modern IOL formulas.

Effect of Pharmacologic Pupil Dilation on OLCR Optical Biometry Measurements for IOL Predictions

2014 ◽  
Vol 24 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Pedro Arriola-Villalobos ◽  
David Díaz-Valle ◽  
Nuria Garzon ◽  
Jorge Ruiz-Medrano ◽  
Cristina Fernández-Pérez ◽  
...  
Keyword(s):  
Pupil Dilation ◽  
Optical Biometry

scholarly journals Determination of the density of human nuclear cataract lenses

2013 ◽  
Vol 8 (5) ◽  
pp. 1300-1304 ◽  
Author(s):  
KE XU ◽  
YANSHENG HAO
Keyword(s):  
Nuclear Cataract
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