Ion homeostasis and interrenal stress responses in juvenile Pacific herring, Clupea pallasi, exposed to the water-soluble fraction of crude oil

2005 ◽  
Vol 323 (1) ◽  
pp. 43-56 ◽  
Author(s):  
Christopher J. Kennedy ◽  
Anthony P. Farrell
Keyword(s):  
Crude Oil ◽  
Stress Responses ◽  
Soluble Fraction ◽  
Ion Homeostasis ◽  
Water Soluble ◽  
Pacific Herring ◽  
Water Soluble Fraction ◽  
Clupea Pallasi

scholarly journals Nephrotoxicological Effect of Water Soluble Fraction of Bonny Light Crude Oil in Wistar Albino Rats

2019 ◽  
pp. 1-9
Author(s):  
Abraham, Chiedozie Nicholas ◽  
J. Udom, Godwin ◽  
C. Patrick-Iwuanyanwu, Kingsley
Keyword(s):  
Crude Oil ◽  
Soluble Fraction ◽  
Water Soluble ◽  
Albino Rats ◽  
Renal Tubules ◽  
Water Soluble Fraction ◽  
Light Crude Oil ◽  
Range Finding ◽  
Effect Of Water ◽  
Wistar Albino Rats

This study evaluated the Nephrotoxic effect of water soluble fraction (WSF) of Bonny Light Crude Oil (BLCO). After preparation of the WSF and a range finding test, the Wistar albino rats were administered three concentrations (25%, 50% and 100%) of WSF of BLCO for 30 and 60days. Data from the study showed that Urea concentration increased significantly (p≤0.05) with increasing dose of BLCO ranging from 14.71 mg/dl in the control to 35.28 mg/dl in the 100% group after 30days and 14.28 mg/dl in the control to 41.08mg/dl in the 100% group after 60days, Creatinine concentration increased significantly (p≤0.05) from 0.22 mg/dl in the control to 0.82mg/dl in the 100% group after 60 days administration while electrolyte (Na, K, Cl) concentration increased significantly (p≤0.05) with increasing dose of BLCO after 60days administration. Histopathological examination of the kidney was characterized by partial partitioning of the glomerular tufts, obliteration of the Bowman’s capsule and distortion of the renal tubules. The findings in this research suggest that WSF of BLCO induced nephrotoxicity.

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