Water extract of Armillaria mellea (Vahl) P. Kumm. Alleviates the depression-like behaviors in acute- and chronic mild stress-induced rodent models via anti-inflammatory action

2021 ◽  
Vol 265 ◽  
pp. 113395
Author(s):  
Yu-En Lin ◽  
Hsiang-Lan Wang ◽  
Kuan-Hung Lu ◽  
Yun-Ju Huang ◽  
Suraphan Panyod ◽  
...  
Keyword(s):  
Water Extract ◽  
Chronic Mild Stress ◽  
Mild Stress ◽  
Rodent Models ◽  
Armillaria Mellea ◽  
Anti Inflammatory ◽  
Inflammatory Action

scholarly journals Anti-inflammatory Action of Water Extract of Snake's Moulted Skin

1980 ◽  
Vol 100 (6) ◽  
pp. 662-667
Author(s):  
YOSHIMASA MIYAKE ◽  
TOSHIKO ITO
Keyword(s):  
Water Extract ◽  
Anti Inflammatory ◽  
Inflammatory Action

scholarly journals Antidepressant-like Effects of Schisandra chinensis Baillon Water Extract on Animal Model Induced by Chronic Mild Stress

2014 ◽  
Vol 22 (3) ◽  
pp. 196-202 ◽  
Author(s):  
Min Gu Kang ◽  
Young Hwa Kim ◽  
A Rang Im ◽  
Byung Soo Nam ◽  
Sung Wook Chae ◽  
...  
Keyword(s):  
Animal Model ◽  
Water Extract ◽  
Chronic Mild Stress ◽  
Mild Stress ◽  
Schisandra Chinensis

scholarly journals Daidzein Alleviates Hypothalamic-Pituitary-Adrenal Axis Hyperactivity, Ameliorates Depression-Like Behavior, and Partly Rectifies Circulating Cytokine Imbalance in Two Rodent Models of Depression

2021 ◽  
Vol 15 ◽  
Author(s):  
Long Chen ◽  
Xiaokun Wang ◽  
Yunpeng Zhang ◽  
Hequan Zhong ◽  
Cuiting Wang ◽  
...  
Keyword(s):  
Hpa Axis ◽  
Learned Helplessness ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Chronic Mild Stress ◽  
Mental Health Disorder ◽  
Mild Stress ◽  
Rodent Models ◽  
Hypothalamic Pituitary Adrenal ◽  
Simultaneous Evaluation ◽  
Antidepressant Effects

Depression is one very common mental health disorder which can cause morbidity and mortality if not addressed. Recent studies have provided strong evidence that depression may be accompanied by immune activation, secondary inflammatory reaction, and hyperactivity of the Hypothalamic Pituitary Adrenal (HPA) axis. It is well-known that it takes at least 2 weeks for conventional antidepressants, especially SSRIs (Selective serotonin reuptake inhibitors) to produce effects. To better understand the mechanism of antidepressant effects on depression and subsequently further elucidate the pathogenesis of depression, we selected phytestrogen daidzein (DD) to observe its effects on the depression-like and anxiety-like behavior in two different rodent models of depression which were induced by learned helplessness and chronic mild stress (CMS) and then simultaneous evaluation of the depression-like behavior, the activity of HPA axis, and circulatory cytokines. Our results showed that daidzein attenuated depression-like behaviors through alleviating HPA axis hyperactivity, decreasing the levels of stress-related hormones, and partly rectifying some inflammatory cytokines imbalance in both the rodent models of depression.

Pro- and anti-inflammatory cytokines expression in rat's brain and spleen exposed to chronic mild stress: Involvement in depression

2011 ◽  
Vol 225 (1) ◽  
pp. 135-141 ◽  
Author(s):  
Zili You ◽  
Chunmei Luo ◽  
Wenzheng Zhang ◽  
Yubo Chen ◽  
Jiajia He ◽  
...  
Keyword(s):  
Inflammatory Cytokines ◽  
Chronic Mild Stress ◽  
Mild Stress ◽  
Anti Inflammatory
Sign in / Sign up

Export Citation Format

Share Document