Three novel friedelane triterpenes, monospermonal, monospermonol and monospermondiol, along with six known friedelanes, 3-oxofriedelane, 3-oxofriedelan-28-al, 3,12-dioxofriedelane, 3-oxo-28-hydroxyfriedelane, 3-oxo-11 β-hydroxyfriedelane, 3-oxo-12 α-hydroxyfriedelane and an oleanane triterpenoid, 3 β-hydroxyolean-12-ene, were isolated from the stems of Celastrus monospermus Roxb. The structures of novel compounds, monospermonal, monospermonol and monospermondiol, were identified as 3,12-dioxofriedelan-28-al, 3,12-dioxo-28-hydroxyfriedelane and 3-oxo-12 α,28-dihydroxyfriedelane, respectively by spectroscopies including 2D NMR methods. These nine friedelane-type triterpenes were tested for antimicrobial activity against luminescent bacterium Photobacterium leiognathi N1 that had been isolated from “glowing” fish meat. Monospermonal and monospermonol showed moderate activity.
Bioactive assessment of the antioxidative and antidiabetic activities of oleanane triterpenoid isolates of sprouted quinoa yoghurt beverages and their anti-angiogenic effects on HUVECS line
