Dynamical analysis of a nonlocal delayed and diffusive HIV latent infection model with spatial heterogeneity

Author(s):  
Peng Wu ◽  
Hongyong Zhao
2015 ◽  
Vol 2015 ◽  
pp. 1-15 ◽  
Author(s):  
Zizhen Zhang ◽  
Huizhong Yang

This paper is devoted to the study of an SIRS computer virus propagation model with two delays and multistate antivirus measures. We demonstrate that the system loses its stability and a Hopf bifurcation occurs when the delay passes through the corresponding critical value by choosing the possible combination of the two delays as the bifurcation parameter. Moreover, the direction of the Hopf bifurcation and the stability of the bifurcating periodic solutions are determined by means of the center manifold theorem and the normal form theory. Finally, some numerical simulations are performed to illustrate the obtained results.


Author(s):  
Xiang Yu ◽  
Lihua Lu ◽  
Jianyi Shen ◽  
Jiandun Li ◽  
Wei Xiao ◽  
...  

2019 ◽  
Vol 354 ◽  
pp. 266-281 ◽  
Author(s):  
M. Prakash ◽  
R. Rakkiyappan ◽  
A. Manivannan ◽  
Jinde Cao

2018 ◽  
Vol 2018 ◽  
pp. 1-14
Author(s):  
Jun Liu ◽  
Yan Wang ◽  
Luju Liu ◽  
Tingting Zhao

Recent studies have demonstrated that the latent infection is a major obstacle to the viral elimination in HIV infection process. In this paper, we formulate a stochastic HIV infection model to include both latent infection and combination drug therapies. We derive that the model solution is unique and positive, and the solution is global. By constructing appropriate stochastic Lyapunov functions, the existence of an ergodic stationary distribution is obtained when the critical condition is greater than one. Furthermore, through rigorous analysis and deduction, the extinction of the virus is established under certain conditions. Numerical simulations are performed to show that small intensity of white noises can maintain the existence of a stationary distribution, while large intensity of white noises is beneficial to the extinction of the virus.


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