The impact of colorectal surgery on health-related quality of life in older functionally dependent patients with cancer – A longitudinal follow-up study

2019 ◽  
Vol 10 (5) ◽  
pp. 724-732 ◽  
Author(s):  
Esteban T.D. Souwer ◽  
Simone Oerlemans ◽  
Lonneke V. van de Poll-Franse ◽  
Felice N. van Erning ◽  
Frederiek van den Bos ◽  
...  
2008 ◽  
Vol 107 (6) ◽  
pp. 1957-1964 ◽  
Author(s):  
José G. M. Hofhuis ◽  
Peter E. Spronk ◽  
Henk F. van Stel ◽  
Augustinus J. P. Schrijvers ◽  
Johannes H. Rommes ◽  
...  

Author(s):  
Cynthia S. Bonhof ◽  
Lonneke V. van de Poll-Franse ◽  
Dareczka K. Wasowicz ◽  
Laurens V. Beerepoot ◽  
Gerard Vreugdenhil ◽  
...  

Abstract Purpose To gain more insight into the course of chemotherapy-induced peripheral neuropathy (CIPN) and its impact on health-related quality of life (HRQoL) in a population-based sample of colorectal cancer (CRC) patients up to 2 years after diagnosis. Methods All newly diagnosed CRC patients from four hospitals in the Netherlands were eligible for participation in an ongoing prospective cohort study. Patients (n = 340) completed questions on CIPN (EORTC QLQ-CIPN20) and HRQoL (EORTC QLQ-C30) before initial treatment (baseline) and 1 and 2 years after diagnosis. Results Among chemotherapy-treated patients (n = 105), a high sensory peripheral neuropathy (SPN) level was reported by 57% of patients at 1 year, and 47% at 2-year follow-up, whereas a high motor peripheral neuropathy (MPN) level was reported by 47% and 28%, at years 1 and 2, respectively. Linear mixed model analyses showed that SPN and MPN symptoms significantly increased from baseline to 1-year follow-up and did not return to baseline level after 2 years. Patients with a high SPN or MPN level reported a worse global quality of life and a worse physical, role, emotional, cognitive, and social functioning compared with those with a low SPN or MPN level. Conclusions Future studies should focus on understanding the mechanisms underlying CIPN so targeted interventions can be developed to reduce the impact of CIPN on patient’s lives. Implications for cancer survivors Patients need to be informed of both CIPN and the impact on HRQoL.


2009 ◽  
Vol 10 (1) ◽  
Author(s):  
Inger Hallberg ◽  
Margareta Bachrach-Lindström ◽  
Staffan Hammerby ◽  
Göran Toss ◽  
Anna-Christina Ek

2019 ◽  
Vol 28 (12) ◽  
pp. 3225-3236 ◽  
Author(s):  
Joonas Taipale ◽  
Alexandra Mikhailova ◽  
Matti Ojamo ◽  
Janika Nättinen ◽  
Saku Väätäinen ◽  
...  

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