Colorimetric aptasensor for ochratoxin A detection based on enzyme-induced gold nanoparticle aggregation

2020 ◽  
Vol 388 ◽  
pp. 121758 ◽  
Author(s):  
Yue He ◽  
Fengyu Tian ◽  
Jing Zhou ◽  
Qiyang Zhao ◽  
Ruijie Fu ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Ochratoxin A ◽  
Nanoparticle Aggregation ◽  
Gold Nanoparticle Aggregation ◽  
Colorimetric Aptasensor

scholarly journals CRISPR/Cas12a-mediated gold nanoparticle aggregation for colorimetric detection of SARS-CoV-2

2021 ◽  
Author(s):  
Yiren Cao ◽  
Jinjun Wu ◽  
Bo Pang ◽  
Hongquan Zhang ◽  
X. Chris Le
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Colorimetric Detection ◽  
Isothermal Amplification ◽  
Nanoparticle Aggregation ◽  
Cleavage Activity ◽  
Gold Nanoparticle Aggregation

The trans-cleavage activity of the target-activated CRISPR-Cas12a liberated an RNA crosslinker from a molecular transducer, which facilitated assembly of gold nanoparticles. Integration of the molecular transducer with isothermal amplification and...

Mannitol-induced gold nanoparticle aggregation for the ligand-free detection of viral particles

The Analyst ◽  
2019 ◽  
Vol 144 (18) ◽  
pp. 5486-5496 ◽  
Author(s):  
Xue Mi ◽  
Elizabeth M. Lucier ◽  
Dylan G. Turpeinen ◽  
Eugenia Li Ling Yeo ◽  
James Chen Yong Kah ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Prior Knowledge ◽  
Nanoparticle Aggregation ◽  
Viral Particles ◽  
Gold Nanoparticle Aggregation ◽  
Ligand Free ◽  
Specific Virus ◽  
P Addition

Addition of osmolytes causes viruses-coated AuNPs to aggregate and not protein-coated AuNPs. Ligand-free detection of virus was developed without the need for prior knowledge of the specific virus target.

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