Exome-Wide Association Analysis Suggests LRP2BP as a Susceptibility Gene for Endothelial Injury in Systemic Sclerosis in the Han Chinese Population

2020 ◽  
Author(s):  
Weilin Pu ◽  
Wenyu Wu ◽  
Qingmei Liu ◽  
Yanyun Ma ◽  
Wenzhen Tu ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Association Analysis ◽  
Chinese Population ◽  
Susceptibility Gene ◽  
Han Chinese ◽  
Endothelial Injury ◽  
Han Chinese Population

SNX29, a new susceptibility gene shared with major mental disorders in Han Chinese population

2020 ◽  
pp. 1-9
Author(s):  
Jian-Hua Chen ◽  
Ying Zhao ◽  
Raja Amjad Waheed Khan ◽  
Zhi-Qiang Li ◽  
Juan Zhou ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Chinese Population ◽  
Susceptibility Gene ◽  
Han Chinese ◽  
Han Chinese Population

Association analysis of the SOX10 polymorphism with Hirschsprung disease in the Han Chinese population

2011 ◽  
Vol 46 (10) ◽  
pp. 1930-1934 ◽  
Author(s):  
Zhi-Wen Pan ◽  
Jintu Lou ◽  
Chunfen Luo ◽  
Linjun Yu ◽  
Ji-Cheng Li
Keyword(s):  
Association Analysis ◽  
Chinese Population ◽  
Hirschsprung Disease ◽  
Han Chinese ◽  
Han Chinese Population

scholarly journals CACNA1C, schizophrenia and major depressive disorder in the Han Chinese population

2014 ◽  
Vol 204 (1) ◽  
pp. 36-39 ◽  
Author(s):  
Kuanjun He ◽  
Zhiguo An ◽  
Qingzhong Wang ◽  
Tao Li ◽  
Zhiqiang Li ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Chinese Population ◽  
Susceptibility Gene ◽  
Han Chinese ◽  
Major Depressive ◽  
Han Chinese Population ◽  
Risk Gene ◽  
Voltage Dependent ◽  
Shared Risk

BackgroundCommon psychiatric disorders are highly heritable, indicating that genetic factors play an important role in their aetiology. The CACNA1C gene, which codes for subunit alpha-1C of the Cav1.2 voltage-dependent L-type calcium channel, has been consistently found to be the shared risk gene for several kinds of mental disorder.AimsTo investigate whether CACNA1C is a susceptibility gene for schizophrenia and major depressive disorder in the Han Chinese population.MethodWe carried out a case–control study of 1235 patients with schizophrenia, 1045 with major depressive disorder and 1235 healthy controls. A tag single nucleotide polymorphism (SNP) rs1006737 along with another 10 tag SNPs in the CACNA1C gene were genotyped in all samples.ResultsWe found that rs1006737 was associated with both schizophrenia (Pallele = 0.0014, Pgenotype = 0.006, odds ratio (OR) = 1.384, 95% CI 1.134–1.690) and major depressive disorder (Pallele = 0.0007, Pgenotype = 0.003, OR = 1.425, 95% CI 1.160–1.752).ConclusionsOur findings support CACNA1C being a risk gene for both schizophrenia and major depressive disorder in the Han Chinese population.

Association Analysis of the RET Proto-Oncogene with Hirschsprung Disease in the Han Chinese Population of Southeastern China

2010 ◽  
Vol 48 (5-6) ◽  
pp. 496-503 ◽  
Author(s):  
Cui-Ping Liu ◽  
Qian-Qian Tang ◽  
Jin-Tu Lou ◽  
Chun-Fen Luo ◽  
Xue-Wu Zhou ◽  
...  
Keyword(s):  
Association Analysis ◽  
Chinese Population ◽  
Hirschsprung Disease ◽  
Han Chinese ◽  
Southeastern China ◽  
Han Chinese Population

Association analysis between CAMKK2 rs1063843 and patients with schizophrenia in a Han Chinese population

2020 ◽  
Vol 52 ◽  
pp. 102055
Author(s):  
Lu Qian ◽  
Deyi Zhou ◽  
Fuquan Zhang ◽  
Xinyu Chen ◽  
Bixiu Yang ◽  
...  
Keyword(s):  
Association Analysis ◽  
Chinese Population ◽  
Han Chinese ◽  
Han Chinese Population
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