Genome-scale DNA methylation analysis identifies repeat element alterations that modulate the genomic stability of melanocytic nevi

Author(s):  
Meghan E. Muse ◽  
Drew T. Bergman ◽  
Lucas A. Salas ◽  
Lisa N. Tom ◽  
Jean-Marie Tan ◽  
...  
2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Fabian Müller ◽  
Michael Scherer ◽  
Yassen Assenov ◽  
Pavlo Lutsik ◽  
Jörn Walter ◽  
...  

Abstract DNA methylation is a widely investigated epigenetic mark with important roles in development and disease. High-throughput assays enable genome-scale DNA methylation analysis in large numbers of samples. Here, we describe a new version of our RnBeads software - an R/Bioconductor package that implements start-to-finish analysis workflows for Infinium microarrays and various types of bisulfite sequencing. RnBeads 2.0 (https://rnbeads.org/) provides additional data types and analysis methods, new functionality for interpreting DNA methylation differences, improved usability with a novel graphical user interface, and better use of computational resources. We demonstrate RnBeads 2.0 in four re-runnable use cases focusing on cell differentiation and cancer.


2012 ◽  
Vol 56 (1) ◽  
pp. 5-8
Author(s):  
Yoshiyuki Watanabe ◽  
Yoshihito Yoshida ◽  
Ritsuko Oikawa ◽  
Masaki Hara ◽  
Hiroshi Kiyokawa ◽  
...  

Epigenomics ◽  
2010 ◽  
Vol 2 (1) ◽  
pp. 105-117 ◽  
Author(s):  
Shaun D Fouse ◽  
Raman P Nagarajan ◽  
Joseph F Costello

2021 ◽  
Vol 16 (3) ◽  
pp. S490
Author(s):  
D.M. Aguilar-Beltrán ◽  
A.G. Alcázar-Ramos ◽  
A.L. Vega-Rodríguez ◽  
D.G. García-Gutiérrez ◽  
A.D. Bertadillo-Jilote ◽  
...  

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