scholarly journals Towards the prevention of potential aluminum toxic effects and an effective treatment for Alzheimer's disease

2011 ◽  
Vol 105 (11) ◽  
pp. 1505-1512 ◽  
Author(s):  
Maire E. Percy ◽  
Theo P.A. Kruck ◽  
Aileen I. Pogue ◽  
Walter J. Lukiw
1989 ◽  
Vol 155 (2) ◽  
pp. 202-205 ◽  
Author(s):  
A. C. Warren ◽  
S. Holroyd ◽  
M. F. Folstein

Five patients with trisomy 21 (Down's syndrome (DS)), referred to us for evaluation of dementia, were instead found to have major depression. All had shown cognitive and behavioural deterioration and this had led to a mistaken diagnosis of Alzheimer's disease in two. We outline and contrast the features of major depression and Alzheimer's disease in DS, and suggest that electroconvulsive therapy is an effective treatment for major depression in DS.


2018 ◽  
Vol 14 (12) ◽  
pp. 2066-2076 ◽  
Author(s):  
Lixue Fan ◽  
Jiapeng Wang ◽  
Fanrong Meng ◽  
Yuan Luo ◽  
Xin Sui ◽  
...  

2011 ◽  
Vol 21 (4) ◽  
pp. 340-345 ◽  
Author(s):  
James O'Donovan

SummaryAlzheimer's disease (AD) is the commonest form of dementia, estimated to affect 37 million people worldwide. Currently there is nothing to halt the progression of AD – treatment focuses largely on slowing the development of symptoms. More recently disease-modifying interventions, such as immunotherapy, have been investigated as their aim is to halt or even reverse symptoms by removing β-amyloid (Aβ) pathology. This paper assesses the developments made in this particular field, offers critical appraisal of important papers and assesses the viability of this potential form of treatment.


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