Computational Characterization of Structural Role of the Non-active Site Mutation M36I of Human Immunodeficiency Virus Type 1 Protease

Virus Type ◽

Active Site ◽

Site Mutation ◽

Structural Role ◽

An active-site mutation in the human immunodeficiency virus type 1 proteinase (PR) causes reduced PR activity and loss of PR-mediated cytotoxicity without apparent effect on virus maturation and infectivity.

Journal of Virology ◽

10.1128/jvi.69.11.7180-7186.1995 ◽

1995 ◽

Vol 69 (11) ◽

pp. 7180-7186 ◽

Cited By ~ 74

Author(s):

J Konvalinka ◽

M A Litterst ◽

R Welker ◽

H Kottler ◽

F Rippmann ◽

...

Keyword(s):

Virus Type ◽

Active Site ◽

Apparent Effect ◽

Site Mutation ◽

Virus Maturation ◽

Characterization of neutralization epitopes in the V2 region of human immunodeficiency virus type 1 gp120: role of glycosylation in the correct folding of the V1/V2 domain.

Journal of Virology ◽

10.1128/jvi.69.4.2271-2278.1995 ◽

1995 ◽

Vol 69 (4) ◽

pp. 2271-2278 ◽

Cited By ~ 54

Author(s):

Z Wu ◽

S C Kayman ◽

W Honnen ◽

K Revesz ◽

H Chen ◽

...

Keyword(s):

Virus Type ◽

Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor.

Journal of Virology ◽

10.1128/jvi.69.4.2148-2152.1995 ◽

1995 ◽

Vol 69 (4) ◽

pp. 2148-2152 ◽

Cited By ~ 34

Author(s):

A K Patick ◽

R Rose ◽

J Greytok ◽

C M Bechtold ◽

M A Hermsmeier ◽

...

Keyword(s):

Protease Inhibitor ◽

Virus Type ◽

Kinetic studies of human immunodeficiency virus type 1 protease and its active-site hydrogen bond mutant A28S.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54237-x ◽

1991 ◽

Vol 266 (36) ◽

pp. 24359-24366

Author(s):

E. Ido ◽

H.P. Han ◽

F.J. Kezdy ◽

J. Tang

Keyword(s):

Hydrogen Bond ◽

Virus Type ◽

Active Site ◽

Kinetic Studies ◽

Critical Role of Enhanced CD4 Affinity in Laboratory Adaptation of Human Immunodeficiency Virus Type 1

AIDS Research and Human Retroviruses ◽

10.1089/08892220050042819 ◽

2000 ◽

Vol 16 (9) ◽

pp. 871-882 ◽

Cited By ~ 27

Author(s):

Emily J. Platt ◽

Susan L. Kozak ◽

David Kabat

Keyword(s):

Virus Type ◽

Critical Role ◽

Laboratory Adaptation ◽

Genotypic Characterization of Human Immunodeficiency Virus Type 1 Derived from Antiretroviral Therapy-Naive Individuals Residing in Sorong, West Papua

AIDS Research and Human Retroviruses ◽

10.1089/aid.2016.0054 ◽

2016 ◽

Vol 32 (8) ◽

pp. 812-817 ◽

Cited By ~ 7

Author(s):

Adiana Mutamsari Witaningrum ◽

Tomohiro Kotaki ◽

Siti Qamariyah Khairunisa ◽

Muhammad Qushai Yunifiar M ◽

Dwi Wahyu Indriati ◽

...

Keyword(s):

Antiretroviral Therapy ◽

Virus Type ◽

Genotypic Characterization ◽

Immunodeficiency Virus ◽

West Papua

The role of amino acid changes in the human immunodeficiency virus type 1 transmembrane domain in antibody binding and neutralization

Virology ◽

10.1016/j.virol.2011.09.032 ◽

2011 ◽

Vol 421 (2) ◽

pp. 235-244 ◽

Cited By ~ 15

Author(s):

Erica Lovelace ◽

Hengyu Xu ◽

Catherine A. Blish ◽

Roland Strong ◽

Julie Overbaugh

Keyword(s):

Amino Acid ◽

Virus Type ◽

Transmembrane Domain ◽

Antibody Binding ◽

Characterization of neutralizing monoclonal antibodies to linear and conformation-dependent epitopes within the first and second variable domains of human immunodeficiency virus type 1 gp120.

Journal of Virology ◽

10.1128/jvi.67.8.4932-4944.1993 ◽

1993 ◽

Vol 67 (8) ◽

pp. 4932-4944 ◽

Cited By ~ 85

Author(s):

J A McKeating ◽

C Shotton ◽

J Cordell ◽

S Graham ◽

P Balfe ◽

...

Keyword(s):

Monoclonal Antibodies ◽

Virus Type ◽

Immunodeficiency Virus ◽

Variable Domains

Genomic Organization and Functional Characterization of the Chemokine ReceptorCXCR4, a Major Entry Co-receptor for Human Immunodeficiency Virus Type 1

Journal of Biological Chemistry ◽

10.1074/jbc.273.8.4754 ◽

1998 ◽

Vol 273 (8) ◽

pp. 4754-4760 ◽

Cited By ~ 82

Author(s):

Scott A. Wegner ◽

Philip K. Ehrenberg ◽

George Chang ◽

Deborah E. Dayhoff ◽

Alex L. Sleeker ◽

...

Keyword(s):

Virus Type ◽

Genomic Organization ◽

Functional Characterization ◽

Biochemical and immunological characterization of the plant-derived candidate human immunodeficiency virus type 1 mucosal vaccine CTB-MPR649-684

Plant Biotechnology Journal ◽

10.1111/j.1467-7652.2008.00381.x ◽

2009 ◽

Vol 7 (2) ◽

pp. 129-145 ◽

Cited By ~ 44

Author(s):

Nobuyuki Matoba ◽

Hiroyuki Kajiura ◽

Irene Cherni ◽

Jeffrey D. Doran ◽

Morgane Bomsel ◽

...

Keyword(s):

Virus Type ◽

Mucosal Vaccine ◽

Immunological Characterization ◽