Implementation of collagen fiber dispersion in a growth and remodeling model of arterial walls

Author(s):  
Nino Horvat ◽  
Lana Virag ◽  
Gerhard A. Holzapfel ◽  
Igor Karšaj
2006 ◽  
Vol 39 ◽  
pp. S317 ◽  
Author(s):  
I. Hariton ◽  
G. deBotton ◽  
T.C. Gasser ◽  
G.A. Holzapfel

Author(s):  
Ihor Machyshyn ◽  
Peter Bovendeerd ◽  
Fons van de Ven ◽  
Peter Rongen ◽  
Frans van de Vosse

Living tissues continuously undergo growth, i.e. a change in mass, and remodeling, i.e. reorganization or renovation. Modeling both growth and remodeling (G&R) of the vascular tissue is aimed to provide insight into the adaptation of the tissue, in the healthy and diseased state, and upon surgical intervention. An important aspect is the description of remodeling of collagen fiber direction. Whereas a phenomenological approach for that is suggested in [2], in this study we adopt an approach towards more microstructural approach, along the model in [1].


2006 ◽  
Vol 6 (3) ◽  
pp. 163-175 ◽  
Author(s):  
I. Hariton ◽  
G. deBotton ◽  
T. C. Gasser ◽  
G. A. Holzapfel

Author(s):  
William Wan ◽  
Rudolph L. Gleason

Recent studies have revealed that carotid arteries from fibulin-5 (fbln5) null mice exhibit altered biomechanical and microstructural properties [1–2]. While the previous studies outline quantitative differences in mechanical properties of arteries from fbln5 null and wildtype mice, physical microstructural differences have yet to be quantified. Measurement of microstructural parameters will provide a crucial link between previously quantified mechanical properties and biological effects of knocking out the fbln5 gene. Characterizing microstructural properties will also provide experimental data to validate structurally-motivated constitutive relations and growth and remodeling models [3–4]. In this study, we quantified collagen fiber orientation in carotid arteries from fbln5 null and wildtype mice; collagen in mouse carotid arteries were imaged using multiphoton microscopy and analyzed using a fast Fourier transform algorithm.


1988 ◽  
Author(s):  
Jim Griffith ◽  
Mario Maciel ◽  
Paul Zalesky

eJHaem ◽  
2021 ◽  
Author(s):  
Hannah Van Steenberge ◽  
Francesca Dedeurwaerdere ◽  
Dries Deeren

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