scholarly journals The utility of anti-SOX2 antibodies for cancer prediction in patients with paraneoplastic neurological disorders

2019 ◽  
Vol 326 ◽  
pp. 14-18 ◽  
Author(s):  
Paul Maddison ◽  
Maarten J. Titulaer ◽  
Jan J. Verschuuren ◽  
Paul Gozzard ◽  
Bethan Lang ◽  
...  
2012 ◽  
Vol 83 (3) ◽  
pp. e1.135-e1
Author(s):  
P Maddison ◽  
M J Titulaer ◽  
J J G Verschuuren ◽  
P Gozzard ◽  
B Lang ◽  
...  

1999 ◽  
Vol 46 (5) ◽  
pp. 774-777 ◽  
Author(s):  
Albert Saiz ◽  
Francesc Graus ◽  
Josep Dalmau ◽  
Alex Pifarr� ◽  
Concepci� Mar�n ◽  
...  

2004 ◽  
Vol 6 (1) ◽  
pp. 55-62 ◽  
Author(s):  
Steven Vernino ◽  
Brian Patrick O'Neill ◽  
Randolph S. Marks ◽  
Judith R. O'Fallon ◽  
David W. Kimmel

2021 ◽  
Vol 14 ◽  
pp. 175628642098532
Author(s):  
Michelle F. Devine ◽  
Naga Kothapalli ◽  
Mahmoud Elkhooly ◽  
Divyanshu Dubey

We provide an overview of the varied presentations of paraneoplastic neurological syndromes. We also review the onconeural antibodies and their particular oncological and neurological associations. Recognition of these syndromes and their oncological associations is crucial, as early diagnosis and management has been associated with better patient outcomes. Specific management strategies and prognosis vary widely depending on the underlying etiology. An understanding of the relevant clinical details, imaging findings, and other diagnostic information can help tailor treatment approaches. We provide an outline of the diagnostic evaluation and treatment of various paraneoplastic neurological disorders, presenting with central and/or peripheral nervous system involvement. We briefly discuss neurologic immune checkpoint inhibitor-related adverse events, which can occasionally present with paraneoplastic neurological syndrome phenotypes.


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