Premorbid physical activity predicts disability progression in relapsing–remitting multiple sclerosis

2012 ◽  
Vol 323 (1-2) ◽  
pp. 123-127 ◽  
Author(s):  
Robert W. Motl ◽  
Deirdre Dlugonski ◽  
Lara Pilutti ◽  
Brian Sandroff ◽  
Edward McAuley
Keyword(s):  
Physical Activity ◽  
Multiple Sclerosis ◽  
Disability Progression ◽  
Relapsing Remitting ◽  
Remitting Multiple Sclerosis ◽  
Relapsing Remitting Multiple Sclerosis

Parity and disability progression in relapsing–remitting multiple sclerosis

2020 ◽  
Vol 267 (12) ◽  
pp. 3753-3762
Author(s):  
Anat Achiron ◽  
◽  
Alon Ben-David ◽  
Michael Gurevich ◽  
David Magalashvili ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Disability Progression ◽  
Relapsing Remitting ◽  
Remitting Multiple Sclerosis ◽  
Relapsing Remitting Multiple Sclerosis

Interferon-beta and disability progression in relapsing-remitting multiple sclerosis

2013 ◽  
Vol 115 ◽  
pp. S65-S69 ◽  
Author(s):  
Jelena Drulovic ◽  
Jelena Kostic ◽  
Sarlota Mesaros ◽  
Irena Dujmovic Basuroski ◽  
Nebojsa Stojsavljevic ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Interferon Beta ◽  
Disability Progression ◽  
Relapsing Remitting ◽  
Remitting Multiple Sclerosis ◽  
Relapsing Remitting Multiple Sclerosis

Evaluating the response to glatiramer acetate in relapsing–remitting multiple sclerosis (RRMS) patients

2014 ◽  
Vol 20 (12) ◽  
pp. 1602-1608 ◽  
Author(s):  
Jordi Río ◽  
Alex Rovira ◽  
Mar Tintoré ◽  
Jaume Sastre-Garriga ◽  
Joaquín Castilló ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Glatiramer Acetate ◽  
Scoring System ◽  
Clinical Activity ◽  
Disability Progression ◽  
Prospective Longitudinal Study ◽  
Relapsing Remitting ◽  
Remitting Multiple Sclerosis ◽  
Relapsing Remitting Multiple Sclerosis ◽  
Prospective Longitudinal

Background: In patients with relapsing–remitting multiple sclerosis (RRMS), a scoring system based on new magnetic resonance imaging (MRI) active lesions, relapses and sustained disability progression after a 1-year treatment with IFNβ predicted patient disability progression over time; however, this score had not been tested in patients receiving glatiramer acetate (GA). Objective: The objective of this study was to evaluate whether this previous scoring system can also be applied to patients treated with GA. Methods: This was a prospective, longitudinal study of 151 RRMS patients treated with GA. Their scores were constructed, based on the clinical and MRI activity after 1 year of therapy. Regression analysis was performed, in order to identify the response variables. Results: The total possible score range was 0–3. Patients with a score of ≥ 2 and those with clinical activity (with or without MRI activity) during their first year of treatment were at increased risk of continuing with relapses and/or sustained disability in the next 2 years (odds ratio (OR): 38.8; p < 0.0001 and OR: 7.8; p < 0.009, respectively). Conclusions: In RRMS patients treated with GA, a combination of clinical activity measures may have prognostic value for identifying patients with disease activity in the next 2 years of therapy.

Symptoms and Physical Activity Among Adults With Relapsing-Remitting Multiple Sclerosis

2010 ◽  
Vol 198 (3) ◽  
pp. 213-219 ◽  
Author(s):  
Robert W. Motl ◽  
Edward McAuley ◽  
Daniel Wynn ◽  
Yoojin Suh ◽  
Madeline Weikert ◽  
...  
Keyword(s):  
Physical Activity ◽  
Multiple Sclerosis ◽  
Relapsing Remitting ◽  
Remitting Multiple Sclerosis ◽  
Relapsing Remitting Multiple Sclerosis
Sign in / Sign up

Export Citation Format

Share Document