Local rate of Jarisch-Herxheimer reaction following penicillin treatment for syphilis during pregnancy

2020 ◽  
Vol 42 (5) ◽  
pp. 689
Author(s):  
Vanessa Poliquin ◽  
Amreet Dhaliwal ◽  
Alison Lopez ◽  
Jared Bullard
1979 ◽  
Vol 92 (3) ◽  
pp. 497-503 ◽  
Author(s):  
P. G. Saffman

It is shown that a symmetrical vortex pair consisting of equal and opposite vortices approaching a plane wall at right angles must approach the wall monotonically in the absence of viscous effects. An approximate calculation is carried out for uniform vortices in which the vortices are assumed to be deformed into ellipses whose axis ratio is determined by the local rate of strain according to the results of Moore & Saffman (1971).


BMJ ◽  
1946 ◽  
Vol 2 (4461) ◽  
pp. 8-10 ◽  
Author(s):  
R. J. Dodds
Keyword(s):  

Heart ◽  
1962 ◽  
Vol 24 (1) ◽  
pp. 39-46 ◽  
Author(s):  
L. P. Garrod ◽  
P. M. Waterworth

2008 ◽  
Vol 14 (6) ◽  
pp. 562-568 ◽  
Author(s):  
Eric M. Roberts ◽  
Paul B. English ◽  
Michelle Wong ◽  
Craig Wolff ◽  
Makinde Falade
Keyword(s):  

Author(s):  
Samaniego Haro VJ ◽  

Syphilis is a disease that has not been eradicated in part due to inadequate management of antibiotic therapy which is selected according to the stage of the disease and to the misuse of the type of penicillin. Treatment of this disease should be done to prevent it´s chronic complications, to avoid infecting sexual partners and the fetus in a pregnant woman. Syphilis in pregnancy causes increase in the rate of recurrent abortions and neonatal morbidity and mortality, that´s the main reason why early detection and treatment without delay is extremely important. Pregnancy alters immunity, so the serological diagnosis can provide false positives, with the use of inverse algorithms these results may decrease, by increasing the sensitivity of the tests. Today, after 69 years since the advent of penicillin, it has become the drug of choice for any stage of syphilis and in pregnant women; if the patient has allergy, desensitization is indicated either orally or intravenously and other antibiotic shouldn´t be used because of the security offered by penicillin in the cure rate and in the reduction of congenital syphilis. Keywords: Syphilis; Pregnancy; Inverse algorithms.


PEDIATRICS ◽  
1976 ◽  
Vol 58 (3) ◽  
pp. 378-381 ◽  
Author(s):  
Abel Paredes ◽  
Larry H. Taber ◽  
Martha D. Yow ◽  
Dorothy Clark ◽  
William Nathan

For more than 30 years, penicillin has been the agent of choice for pneumococcal infections. During this time the majority of strains of Streptococcus pneumoniae have been highly susceptible to penicillin. However, during the last ten years there have been sporadic reports of pneumococci with increased resistance to penicillin. The case report of an 18-month-old white boy with meningitis due to a strain of S. pneumoniae with increased resistance to penicillin is presented. The MIC of the organism to penicillin was 0.2µg/ml and the MBC 0.39µg/ml. The patient had normal immunity and no demonstrable sequestered focus of infection but failed to respond to appropriate doses of intravenous penicillin. Treatment with chloramphenicol caused a dramatic bacteriologic and clinical response. This experience reemphasizes the existence of pneumococcal strains of intermediate penicillin sensitivity and the importance of in vitro susceptibility tests.


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