Syphilis and pregnancy: Review

2021 ◽  
Vol 2 (3) ◽  
Author(s):  
Samaniego Haro VJ ◽  
Keyword(s):  
Pregnant Woman ◽  
Congenital Syphilis ◽  
Neonatal Morbidity ◽  
Sexual Partners ◽  
Cure Rate ◽  
Chronic Complications ◽  
Drug Of Choice ◽  
Recurrent Abortions ◽  
Penicillin Treatment ◽  
In Pregnancy

Syphilis is a disease that has not been eradicated in part due to inadequate management of antibiotic therapy which is selected according to the stage of the disease and to the misuse of the type of penicillin. Treatment of this disease should be done to prevent it´s chronic complications, to avoid infecting sexual partners and the fetus in a pregnant woman. Syphilis in pregnancy causes increase in the rate of recurrent abortions and neonatal morbidity and mortality, that´s the main reason why early detection and treatment without delay is extremely important. Pregnancy alters immunity, so the serological diagnosis can provide false positives, with the use of inverse algorithms these results may decrease, by increasing the sensitivity of the tests. Today, after 69 years since the advent of penicillin, it has become the drug of choice for any stage of syphilis and in pregnant women; if the patient has allergy, desensitization is indicated either orally or intravenously and other antibiotic shouldn´t be used because of the security offered by penicillin in the cure rate and in the reduction of congenital syphilis. Keywords: Syphilis; Pregnancy; Inverse algorithms.

Infections Caused by Spirochetes: Syphilis, Lyme Disease, Leptospirosis

2018 ◽  
Author(s):  
Patrick Duff
Keyword(s):  
Lyme Disease ◽  
Latent Infection ◽  
Congenital Syphilis ◽  
Ixodes Scapularis ◽  
Severe Disease ◽  
Erythema Migrans ◽  
Treponema Pallidum ◽  
Mild Disease ◽  
Drug Of Choice ◽  
In Pregnancy

Syphilis is caused by the spirochete Treponema pallidum. It is classified as primary, secondary, tertiary, and latent infection. If left untreated, syphilis can cause devastating injury to the fetus. The drug of choice for treatment of syphilis in pregnancy is penicillin. Lyme disease is caused by Borrelia burgdorferi and is transmitted by the Ixodes scapularis tick. The principal clinical manifestation of Lyme disease is erythema migrans, but patients may also develop arthritis and cardiac and neurologic abnormalities. Congenital Lyme disease has not been reported. The drug of choice for treatment of Lyme disease in pregnancy is amoxicillin. Leptospirosis is usually acquired from direct contact with urine of infected animals or through contaminated water, soil, or vegetation. Pregnant women with mild disease should be treated with oral amoxicillin. Patients with severe disease should be hospitalized and treated with intravenous penicillin or ampicillin. This review contains 5 figures, 5 tables, and 19 references. Key Words: clinical infection, congenital syphilis, latent infection, leptospirosis, Lyme disease, syphilis

Infections Caused by Spirochetes: Syphilis, Lyme Disease, Leptospirosis

2018 ◽  
Author(s):  
Patrick Duff
Keyword(s):  
Lyme Disease ◽  
Latent Infection ◽  
Congenital Syphilis ◽  
Ixodes Scapularis ◽  
Severe Disease ◽  
Erythema Migrans ◽  
Treponema Pallidum ◽  
Mild Disease ◽  
Drug Of Choice ◽  
In Pregnancy

Syphilis is caused by the spirochete Treponema pallidum. It is classified as primary, secondary, tertiary, and latent infection. If left untreated, syphilis can cause devastating injury to the fetus. The drug of choice for treatment of syphilis in pregnancy is penicillin. Lyme disease is caused by Borrelia burgdorferi and is transmitted by the Ixodes scapularis tick. The principal clinical manifestation of Lyme disease is erythema migrans, but patients may also develop arthritis and cardiac and neurologic abnormalities. Congenital Lyme disease has not been reported. The drug of choice for treatment of Lyme disease in pregnancy is amoxicillin. Leptospirosis is usually acquired from direct contact with urine of infected animals or through contaminated water, soil, or vegetation. Pregnant women with mild disease should be treated with oral amoxicillin. Patients with severe disease should be hospitalized and treated with intravenous penicillin or ampicillin. This review contains 5 figures, 5 tables, and 19 references. Key Words: clinical infection, congenital syphilis, latent infection, leptospirosis, Lyme disease, syphilis

Cholangiocarcinoma in pregnancy (clinical case)

2020 ◽  
pp. 19-27
Author(s):  
A. Yu. Ralnikova ◽  
V. F. Bezhenar ◽  
B. V. Arakelyan ◽  
N. A. Tatarova ◽  
M. E. Malysheva
Keyword(s):  
Pregnant Woman ◽  
Clinical Case ◽  
Clinical Observation ◽  
Late Diagnosis ◽  
Biliary Cancer ◽  
In Pregnancy

The article discusses the problems of diagnosing biliary cancer during pregnancy, proceeding under the guise of complications associated with gestation. A clinical observation of late diagnosis of cholangiocarcinoma in a pregnant woman is presented.

scholarly journals Abordagem conceitual sobre a sífilis na gestação e o tratamento de parceiros sexuais

2011 ◽  
Vol 2 (2) ◽  
pp. 108-111 ◽  
Author(s):  
Dayanne Rakelly De Oliveira ◽  
Mayanne Santana Nóbrega De Figueiredo
Keyword(s):  
Public Health ◽  
Sexual Partners ◽  
Control Measures ◽  
Health It ◽  
The Public ◽  
And Control ◽  
In Pregnancy

Este texto tem como objetivo trazer considerações epidemiológicas e conceituais sobre a sífilis, o tratamento de parceiros sexuais e a inserção do enfermeiro em ações de prevenção e controle desse importante agravo à saúde pública. Enfatiza os aspectos relacionados às medidas de controle dos casos, à terapêutica da doença e à magnitude das complicações visando a contribuir para o aprofundamento da temática e reflexão da prática profissional.Descritores: Sífilis, Parceiros Sexuais, Enfermagem, Saúde Pública.Conceptual approach on syphilis in pregnancy and the treatment of sexual partnersThis text aims to bring epidemiological and conceptual considerations on syphilis, the treatment of sexual partners and the insertion of the nurse in prevention actions and control of this relevant grievance to the public health. It emphasizes the aspects related to control measures of the cases, to the therapeutics of disease and the magnitude of the complications seeking to contribute to the deepening of the theme and the reflection of professional practice.Descriptors: Syphilis, Sexual Partners, Nursing, Public Health.Abordaje conceptual sobre la sífilis en la gestación y lo tratamiento de las parejas sexualesEnfoque conceptual de la sífilis en el embarazo y el tratamiento de las parejas sexuales. Este texto tiene como objetivo integrar consideraciones conceptuales y epidemiológicas sobre la sífilis, el tratamiento de las parejas sexuales y la inclusión de los enfermeros en la prevención y control de este importante agravio de salud pública. Destaca los aspectos relacionados con los casos, con la terapéutica de la enfermedad y con la magnitud de las complicaciones con el objetivo de contribuir a la profundización de la temática y la reflexión de la práctica profesional.Descriptores: Sífilis, Las Parejas Sexuales, Enfermería, Salud Pública.

scholarly journals Quality assessment of praziquantel tablets sold in medicine stores in Kano Metropolis

2018 ◽  
Vol 11 (1) ◽  
pp. 208-210
Author(s):  
M.A. Gadanya ◽  
K.A. Ahmad
Keyword(s):  
Standard Dose ◽  
Poor Quality ◽  
Regulatory Agencies ◽  
Cure Rate ◽  
Quality Cost ◽  
Expiry Date ◽  
Drug Of Choice ◽  
Praziquantel Treatment ◽  
Control Programmes

The efficacy, availability, tolerable side effects and relative affordability of praziquantel makes it the drug of choice in the treatment and various control programmes of schistosomiasis in the endemic areas with excellent outcomes. However, there are reports of low cure rate with praziquantel observed by clinicians with various speculations on the likely causes. This study explored poor drug quality as a possible cause of praziquantel treatment failure in schistosomiasis. On the spot sampling of twelve different samples of praziquantel tablets from various patent medicine shops in Kano metropolis were assayed for active ingredient using British Pharmacopeia methods. Only 6 out of 12 (50%) of the praziquantel tablets studied were found to be acceptable of quality. Cost and number of months before expiry date were not found to be significantly associated with the quality of the drug. Poor quality praziquantel currently in the market may possibly explain failure of standard dose of the drug in the treatment of schistosomiasis. Therefore, it is recommended that additional vigilance by regulatory agencies is required to ensure quality drugs in the market.Keywords: Efficacy, Kano, praziquantel, quality, schistosomiasis

Lethal Vertebral Artery Dissection in Pregnancy: A Case Report and Review of the Literature

2006 ◽  
Vol 130 (4) ◽  
pp. 533-535 ◽  
Author(s):  
Madalina Tuluc ◽  
Daniel Brown ◽  
Bruce Goldman
Keyword(s):  
Case Report ◽  
Pregnant Woman ◽  
Subarachnoid Hemorrhage ◽  
Vertebral Artery ◽  
Fatal Outcome ◽  
Vertebral Artery Dissection ◽  
Rare Event ◽  
Artery Dissection ◽  
Review Of The Literature ◽  
In Pregnancy

Abstract Subarachnoid hemorrhage represents a rare event in pregnancy with a high mortality rate. We present the case of a 39-year-old pregnant woman who developed right vertebral artery dissection with subsequent massive subarachnoid hemorrhage with fatal outcome. The macroscopic and microscopic autopsy findings are described. A review of the literature with a discussion of the varied predisposing factors for vertebral artery dissection and subarachnoid hemorrhage and the rarity of these events in pregnancy is provided.

Male Adolescents Involved in Pregnancy: Associated Health Risk and Problem Behaviors

PEDIATRICS ◽  
1996 ◽  
Vol 98 (2) ◽  
pp. 262-268
Author(s):  
Roger W. Spingarn ◽  
Robert H. DuRant
Keyword(s):  
Logistic Regression ◽  
Health Risk ◽  
Risk Behavior ◽  
Problem Behaviors ◽  
Young Men ◽  
Sexual Partners ◽  
Stepwise Logistic Regression ◽  
Cocaine Use ◽  
Male Adolescents ◽  
In Pregnancy

Objective. Little is known about male high school students who have been involved in a pregnancy. This study was undertaken to determine whether male involvement with a pregnancy during adolescence is associated with other risk and problem behaviors. Methods. The 1993 Massachusetts Youth Risk Behavior Survey was conducted on a random sample of 3054 9th- through 12th-grade students. The use of tobacco, alcohol, and other drugs, early and multiple sexual experiences, fighting resulting in injury, and demographic variables were compared between sexually active young men who reported being involved in pregnancy (n = 82) and their counterparts who reported not ever causing a pregnancy (n = 537). Associations were measured using x2 analyses and Kruskal-Wallis analysis of variance. Stepwise logistic regression was used to further analyze those variables significantly associated with involvement with a pregnancy. Results. Based on logistic regression, older age and earlier ages of onset of cocaine use, initial sexual intercourse, and regular use of cigarettes were associated with being involved with a pregnancy. An increased lifetime frequency of cocaine use, lifetime frequency of alcohol use, and an increased number of lifetime sexual partners were also associated with having caused a pregnancy. Those who reported involvement with a pregnancy reported a higher frequency of being injured in a fight during the past year, drinking while driving, and having multiple sexual partners during the previous 30 days than those who had not gotten someone pregnant. Conclusions. A history of being involved with a pregnancy clustered with other health risk and problem behaviors to form a "risk behavior syndrome." These findings suggest that when risk behaviors are encountered during the routine comprehensive screening of male adolescents, strategies for pregnancy prevention among young men should also be emphasized.

The skin in pregnancy

2010 ◽  
pp. 2149-2153
Author(s):  
Fenella Wojnarowska
Keyword(s):  
Pregnant Woman ◽  
Intrahepatic Cholestasis ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Cholestasis Of Pregnancy ◽  
In Pregnancy

Pregnancy dermatoses are common, and because they are usually very itchy may ruin the life of the pregnant woman. It is particularly important to recognize when itch is due to intrahepatic cholestasis of pregnancy, which has important implications for the health of both mother and fetus (see ...

scholarly journals Intimate partner violence among postpartum women at a teaching hospital in Nigeria’s Federal Capital City: pattern and materno-fetal outcomes

2020 ◽  
Vol 14 ◽  
pp. 263349412092834
Author(s):  
Godwin O. Akaba ◽  
Habiba I. Abdullahi
Keyword(s):  
Intimate Partner Violence ◽  
Teaching Hospital ◽  
Partner Violence ◽  
Intimate Partner ◽  
Sexual Partners ◽  
Postpartum Women ◽  
Fetal Outcomes ◽  
The Past ◽  
Increased Risk ◽  
In Pregnancy

Background: Intimate partner violence is an important public health and human rights issue. Previous studies have considered intimate partner violence in pregnancy mainly among pregnant women attending antenatal clinics thereby missing out a few who may encounter this problem in late pregnancy or just before delivery. This study had the objective of ascertaining the prevalence, pattern of intimate partner violence, and associated materno-fetal outcomes. Method: This was a cross-sectional study conducted between January 2017 and June 2017 among postpartum mothers at a Nigerian Teaching Hospital just before being discharged home. The abuse assessment score was adapted and used to interview women regarding possible intimate partner violence experiences within the past 1 year and during the pregnancy after obtaining written consent. Results: Out of 349 postpartum women interviewed, 102/349 (29.2%) experienced intimate partner violence in the past 1 year, while 18/349 (5.2%) of intimate partner violence occurred in the index pregnancy. Sexual partners were the main perpetuators of intimate partner violence, 67/102 (65.7%), while 35/102 (34.3%) were by someone else other than their sexual partners. Among those abused in the current pregnancy, 10/18 (55.6%) were abused once and the remaining 8/18 (44.4%) were abused more than once. Intimate partner violence was associated with higher chances of cesarean section ( p = 0.001), increased risk of lesser birth weight babies ( p = 0.014), and maternal complications in pregnancy ( p = 0.030). Conclusion: The prevalence of intimate partner violence in pregnancy in Abuja is high with associated poor materno-fetal outcomes. Enforcing existing legislations and screening for intimate partner violence during routine antenatal care may help reduce its prevalence and ensure a positive pregnancy experience for Nigerian women.

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