congenital syphilis
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2022 ◽  
Vol 7 ◽  
pp. 100127
Carolina Santos Souza Tavares ◽  
Sheila Jaqueline Gomes dos Santos Oliveira ◽  
Vanessa Tavares de Gois-Santos ◽  
Andreia Centenaro Vaez ◽  
Max Oliveira de Menezes ◽  

2022 ◽  
Vol 7 ◽  
pp. 100163
Rafael Pinto ◽  
Ricardo Valentim ◽  
Lyrene Fernandes da Silva ◽  
Gustavo Fontoura de Souza ◽  
Thaísa Góis Farias de Moura Santos Lima ◽  

2022 ◽  
Vol 12 (1) ◽  
Joelma Alexandra Ruberti Medeiros ◽  
Mellina Yamamura ◽  
Zilda Pereira da Silva ◽  
Carmen Silvia Bruniera Domingues ◽  
Eliseu Alves Waldman ◽  

AbstractWe aimed to estimate the occurrence of syphilis in pregnant women (SPW) and congenital syphilis (CS) in the municipalities of the state of São Paulo (SP) and evaluate their relationship with socioeconomic, demographic, and health care variables. We developed an ecological study based on secondary data of SPW and CS with spatiotemporal components from 645 municipalities in SP including data from 2007 to 2018. We modeled the data in a Bayesian context, considered spatial and temporal random effects, and used binomial negative probability distributions. We found a continuous increase in the relative temporal risk of SPW, from 2007 to 2018, and CS, from 2007 to 2017, when their incidences increased by 8.6 and 6.6 times, respectively. This increase occurred en bloc in practically all municipalities of SP. The increase in SPW was associated with teenage pregnancy, municipalities with a large number of inhabitants, and acquired immunodeficiency syndrome (AIDS) incidence. The increase in CS was associated with municipalities with a large number of inhabitants, incomplete antenatal care, and AIDS incidence. Although actions to control these diseases are required in all municipalities of SP, the identification of high-risk areas points to priority regions for development.

2021 ◽  
Vol 97 (5) ◽  
pp. 88-93
А. V. Vislobokov ◽  
R. A. Khmel'nitskij

The determination of blood parameters allowed us to establish that anemia develops in a number of infectious diseases, which is called "anemia of inflammation" or anemia of chronic diseases. The article presents a rare clinical case of the development of anemia of the inflammatory response, accompanied by a marked decrease in the content of hemoglobin (less than 110 g/l), hematocrit (less than 30%) and red blood cells (less than 3,0 х 1012/l), in a child with early congenital syphilis with symptoms of: specific rhinitis, papular infiltration, pemphigus, hepatosplenomegaly and damage to the nervous system. As a result of specific treatment with water-soluble benzylpenicillin salt at the rate of 100 U/kg of body weight for 28 days, and transfusion of erythrocyte mass of 15 ml/kg of child weight, there was a parallel regression of clinical manifestations of syphilis with positive dynamics of serological reactions and restoration of the number of red blood cells and the concentration of hemoglobin in the blood.

2021 ◽  
Eunhee Park ◽  
Julie Yip ◽  
Emily Harville ◽  
Marlene Nelson ◽  
Gloria Giarratano ◽  

Abstract Background. Congenital syphilis is preventable through timely access to prenatal care, syphilis screening and treatment of pregnant women diagnosed as infected. In 2018, California had the second highest number of congenital syphilis cases in the United States (U.S.), a nearly 2-fold increase in cases since 2014. This study assessed gaps in preventing congenital syphilis in the high morbidity region of Kern County, California. Methods. Between May 2018 and January 2019, we conducted five focus group discussions with pregnant/postpartum women and ten semi-structured interviews with prenatal care providers in Kern County. Focus group and interview data were recorded, transcribed, and analyzed to identify emergent themes pertaining to facilitators and barriers at each step (prenatal care, syphilis screening and treatment) in the congenital syphilis prevention cascade.Results. Gaps in congenital syphilis prevention discussed in focus group discussions with pregnant/postpartum women were related to limited prenatal care access, social-, economic-, and cultural-barriers, and substance use and co-occurring intimate partner/domestic violence. The gaps identified from interviews with prenatal care providers included social economic vulnerabilities of pregnant women and stigma and shame around the vulnerabilities, distrust in medical system, prenatal substance use, limited prenatal substance use disorder treatment facilities, and inadequate provider training on context-specific congenital syphilis management strategies. Gaps in partner notification, screening and treatment for syphilis were brought up by pregnant/postpartum women and prenatal care providers. Conclusions. Congenital syphilis continues to increase in Kern County and throughout the U.S. In high syphilis morbidity areas, comprehensive and tailored public health approaches addressing setting-specific gaps in prenatal screening and treatment are needed.

2021 ◽  
Vol 4 (6) ◽  
pp. 27642-27658
Beatriz Carvalho de Oliveira ◽  
Eric Pasqualotto ◽  
Jéssica Soares Couto Barbosa ◽  
Vanessa Nascimento Daltro ◽  
Izadora Lima da Cruz ◽  

2021 ◽  
Vol 16 (12) ◽  
pp. 3635-3637
Pg Mohammad Nizam Pg Mohammad Hussein ◽  
Seih Teck Kew ◽  
Khin Mya Nang ◽  
Fairrul Kadir ◽  
Yong Guang Teh

Samantha Pérez-Cavazos ◽  
María Mayela Rodríguez-Saldívar ◽  
Abiel Homero Mascareñas-De los Santos ◽  
José Iván Castillo-Bejarano

2021 ◽  
Vol 4 (6) ◽  
pp. 24588-24597
Laura Di Paiva Gomes e Silva ◽  
Rafaela Lemos Quirino ◽  
Vitor Schroeder Branquinho Reis ◽  
Murilo Schroeder Branquinho Reis ◽  
Jackeline Marianne Chaveiro Tavares

2021 ◽  
Vol 4 (6) ◽  
pp. 24484-24497
Winny Mikaelly Gonçalves Resende ◽  
Giovanna Pimentel Oliveira Silva ◽  
Alessandro Santos Ferreira ◽  
Kaylane Fernanda Lima Santos ◽  
Ítalo Ruan Ribeiro Cruz ◽  

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