Tanezumab, an Anti-Nerve Growth Factor (NGF) antibody, for the treatment of chronic low back pain (CLBP) – a randomized, controlled, double-blind, phase 2 trial

2009 ◽  
Vol 10 (4) ◽  
pp. S42 ◽  
Author(s):  
N. Katz ◽  
D. Borenstein ◽  
C. Birbara ◽  
C. Bramson ◽  
M. Nemeth ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Chronic Low Back Pain ◽  
Low Back ◽  
Phase 2 ◽  
Double Blind ◽  
Randomized Controlled ◽  
Phase 2 Trial

scholarly journals Nerve growth factor antibody for the treatment of osteoarthritis pain and chronic low-back pain

Pain ◽  
2019 ◽  
Vol 160 (10) ◽  
pp. 2210-2220 ◽  
Author(s):  
Martin Schmelz ◽  
Patrick Mantyh ◽  
Anne-Marie Malfait ◽  
John Farrar ◽  
Tony Yaksh ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Chronic Low Back Pain ◽  
Low Back ◽  
Nerve Growth ◽  
Osteoarthritis Pain

Immediate analgesic effect of two modes of short-wave diathermy application in chronic low back pain: study protocol for a randomized controlled trial

2021 ◽  
Author(s):  
Dariel Matheus dos Reis do Nascimento ◽  
Gustavo Cezar Raab Ferreira ◽  
Luiza Helena Silva Gonçalves ◽  
Andressa Mourão de Andrade ◽  
Madeline Luiza Ferreira Pivovarsky ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Controlled Trial ◽  
Short Wave ◽  
Lower Limbs ◽  
Low Back ◽  
Double Blind ◽  
Global Improvement ◽  
Randomized Controlled

The aim of this study is to evaluate and compare the immediate analgesic effects of two applications of short-wave diathermy (SWD) in individuals with chronic low back pain. Randomized, controlled, double-blind clinical trial. A total of 159 participants with chronic low back pain will be randomized in three groups: pulsed mode SWD, continuous mode SWD and placebo. SWD will be applied only once for 30 min. The primary outcomes: intensity and quality of pain. Secondary outcomes: depression and anxiety; perception of global improvement; patient satisfaction; disability and influence of psychosocial factors, strength of the lower limbs and the mobility of the posterior chain. Patients will be evaluated before and after the session and 1 week after. Trial registration number: RBR-2k58f5h Brazilian Registry of Clinical Trials (ReBEC).

Manipulation does not add to the effect of extension exercises in chronic low-back pain (LBP). A randomized, controlled, double blind study

2008 ◽  
Vol 75 (6) ◽  
pp. 708-713 ◽  
Author(s):  
Jens Rasmussen ◽  
Jes Lætgaard ◽  
Anne-Louise Lindecrona ◽  
Etienne Qvistgaard ◽  
Henning Bliddal
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Blind Study ◽  
Double Blind Study ◽  
Low Back ◽  
Double Blind ◽  
Randomized Controlled
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