scholarly journals Chronic Fatigue Syndrome and Chronic Widespread Pain in Adolescence: Population Birth Cohort Study

2017 ◽  
Vol 18 (3) ◽  
pp. 285-294 ◽  
Author(s):  
Tom Norris ◽  
Kevin Deere ◽  
Jon H. Tobias ◽  
Esther Crawley
2008 ◽  
Vol 70 (4) ◽  
pp. 488-495 ◽  
Author(s):  
Samuel B. Harvey ◽  
Michael Wadsworth ◽  
Simon Wessely ◽  
Matthew Hotopf

Author(s):  
Jonathan Price

Fibromyalgia (FM), one of the chronic widespread pain syndromes, and chronic fatigue syndrome (CFS) are important and common conditions. They are considered together here because they are commonly comorbid and because of their similarities—they are long-term conditions with a relatively poor prognosis; central nervous system mechanisms and deconditioning play an important role in aetiology; graded exercise and psychological treatments have an important role in management; and comorbid mental disorders are common and have an adverse impact on important outcomes, including disability and chronicity. The prevalence of FM is rising, while that of CFS is declining. There is increased acceptance of the pivotal role of central nervous system factors in FM, while in CFS, the positions of different aetiological ‘movements’ appear bitterly entrenched. The main focus of this chapter is on FM and, in particular, key aspects of aetiology and treatment, especially those relating to the central nervous system.


CNS Spectrums ◽  
2005 ◽  
Vol 10 (4) ◽  
pp. 281-284 ◽  
Author(s):  
Dan Buskila ◽  
Lily Neumann ◽  
Joseph Press

AbstractRecent evidence suggests that fibromyalgia, a chronic widespread pain condition and related syndromes (chronic fatigue syndrome, irritable bowel syndrome, etc.) may share heritable pathophysiologic features. We review the recent literature on genetic and familial factors found to participate in the pathogenesis of these syndromes, specifically fibromyalgia, including evidence suggesting that serotonin- and dopamine-related genes may play a role in the pathogenesis of these illnesses. The importance of environmental factors triggering these conditions in predisposed individuals is also discussed.


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