Photo Controlled Release of Nitric Oxide (NO) from Amphiphilic and Nanoscale Vesicles Based Ruthenium Nitrosyl Complex: NO release and Cytotoxicity Studies

2021 ◽  
pp. 113703
Author(s):  
Nancy Sharma ◽  
Porkizhi Arjunan ◽  
Srujan Marepally ◽  
Nimisha Jain ◽  
Abbas Raja Naziruddin ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Controlled Release ◽  
Nitrosyl Complex ◽  
Ruthenium Nitrosyl ◽  
Cytotoxicity Studies ◽  
No Release

scholarly journals How does the acidic milieu interfere in the capability of ruthenium nitrosyl complexes to release nitric oxide?

2020 ◽  
Vol 44 (3) ◽  
pp. 773-779
Author(s):  
Renato Pereira Orenha ◽  
Nelson Henrique Morgon ◽  
Julia Contreras-García ◽  
Graziele Cappato Guerra Silva ◽  
Glaucio Régis Nagurniak ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Ruthenium Complexes ◽  
Reduction Reaction ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl ◽  
Release Mechanisms ◽  
No Release

The nitric oxide has a well-defined role in biology. The ruthenium complexes are model for study NO release mechanisms. The proton increases the capability of these compounds to release NO after reduction reaction or of the light supported reaction.

A ruthenium-nitrosyl-functionalized nanoplatform for the targeting of liver cancer cells and NIR-light-controlled delivery of nitric oxide combined with photothermal therapy

2017 ◽  
Vol 5 (38) ◽  
pp. 7831-7838 ◽  
Author(s):  
Yan-Hui Li ◽  
Min Guo ◽  
Shu-Wen Shi ◽  
Qian-Ling Zhang ◽  
Shi-Ping Yang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Liver Cancer ◽  
Cancer Cells ◽  
Photothermal Therapy ◽  
Controlled Delivery ◽  
Liver Cancer Cells ◽  
Ruthenium Nitrosyl ◽  
Nir Light ◽  
No Release

A multifunctional nanoplatform is capable of targeting liver cancer cells for NIR-light-controlled NO-release, and achieving both photodynamic and photothermal therapies.

The Role of π–Donor/Acceptor trans Effect on The NO release in Ruthenium Nitrosyl Complexes: A Computational Insight

2021 ◽  
Author(s):  
Renato Pereira Orenha ◽  
Nelson Morgon ◽  
Graziele Cappato Guerra Silva ◽  
Giovanni Finoto Caramori ◽  
Renato Luis Tame Parreira
Keyword(s):  
Nitric Oxide ◽  
Ruthenium Complexes ◽  
Release Mechanism ◽  
Trans Effect ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl ◽  
No Release ◽  
Donor Acceptor ◽  
Model Structures

The nitric oxide (NO) molecule is associated to diverse biochemical routes. Ruthenium complexes are commonly used as model structures to control the NO availability. Here, the NO release mechanism in...

scholarly journals Two-Photon-Triggered NO Release via a Ruthenium–Nitrosyl Complex with a Star-Shaped Architecture

2020 ◽  
Vol 11 (16) ◽  
pp. 6487-6491
Author(s):  
Margarita Romero Ávila ◽  
Andrés Felipe León-Rojas ◽  
Pascal G. Lacroix ◽  
Isabelle Malfant ◽  
Norberto Farfán ◽  
...  
Keyword(s):  
Nitrosyl Complex ◽  
Two Photon ◽  
Ruthenium Nitrosyl ◽  
No Release

Incorporation of a ruthenium nitrosyl complex into liposomes, the nitric oxide released from these liposomes and HepG2 cell death mechanism

2016 ◽  
Vol 306 ◽  
pp. 701-707 ◽  
Author(s):  
Fernando P. Rodrigues ◽  
Zumira A. Carneiro ◽  
Pradip Mascharak ◽  
Carlos Curti ◽  
Roberto S. da Silva
Keyword(s):  
Nitric Oxide ◽  
Cell Death ◽  
Hepg2 Cell ◽  
Nitrosyl Complex ◽  
Cell Death Mechanism ◽  
Ruthenium Nitrosyl

Effects on mitochondria of mitochondria-induced nitric oxide release from a ruthenium nitrosyl complex

Nitric Oxide ◽  
2009 ◽  
Vol 20 (1) ◽  
pp. 24-30 ◽  
Author(s):  
Cezar R. Pestana ◽  
Daniela P.S. Phelippin ◽  
Ana C.M. Polizello ◽  
Daniel J. Dorta ◽  
Sergio A. Uyemura ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitrosyl Complex ◽  
Nitric Oxide Release ◽  
Ruthenium Nitrosyl

Mechanism and oxidation state involved in the nitric oxide (NO) photorelease in a terpyridine-bipyridine-based ruthenium nitrosyl complex

2018 ◽  
Vol 482 ◽  
pp. 195-205 ◽  
Author(s):  
Valerii Bukhanko ◽  
Pascal G. Lacroix ◽  
Isabelle Sasaki ◽  
Marine Tassé ◽  
Sonia Mallet-Ladeira ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Oxidation State ◽  
Nitrosyl Complex ◽  
Ruthenium Nitrosyl

Light-controlled release of nitric oxide from solid polymer composite materials using visible and near infra-red light

2015 ◽  
Vol 14 (4) ◽  
pp. 775-785 ◽  
Author(s):  
Jonathan D. Mase ◽  
Anton O. Razgoniaev ◽  
Megan K. Tschirhart ◽  
Alexis D. Ostrowski
Keyword(s):  
Nitric Oxide ◽  
Composite Materials ◽  
Controlled Release ◽  
Polymer Composite ◽  
Red Light ◽  
Solid Polymer ◽  
Biocompatible Polymers ◽  
No Donor ◽  
No Release ◽  
Infra Red

Composite materials were prepared using biocompatible polymers, upconverting nanoparticles, and a nitric oxide (NO) donor complex. We have demonstrated NO release from the solid composites after visible and near infra-red light irradiation.

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