Abstract
PurposeThere have been few studies using mindfulness-based stress reduction (MBSR) to improve sexual function in Asian women with breast cancer. This study aimed to evaluate the impact of mindfulness intervention on female sexual function, mental health and quality of life in patients with breast cancer.MethodsFifty-one women with breast cancer were allocated into 6-week MBSR (n=26) session or usual care (n=25), without differences in group characteristics. The research tools included the Female Sexual Function Index (FSFI), the Depression Anxiety Stress Scales-21 (DASS-21), and the EuroQol instrument (EQ-5D). The Greene Climacteric Scale (GCS) was used to verify the foregoing scale. The effects of MBSR were evaluated by the differences between the post- and pre-intervention score in each scale. Statistical analyses consisted of descriptive dataset and Mann-Whitney ranked-pairs test.ResultsAlthough MBSR did not significantly improve sexual desire and depression in patients with breast cancer, MBSR could improve parts of female sexual function [i.e. Δarousal: 5.73 vs. -5.96, Δlubrication: 3.35 vs. -3.48, and Δsatisfaction: 8.48 vs. 1.76; all p <.005] assessed by the FSFI, and mental health [Δanxiety: -10.92 vs.11.36 and Δstress: -10.96 vs.11.40; both p <.001] assessed by the DASS-21.ConclusionOur study revealed that MBSR can improve female sexual function and mental health except sexual desire and depression in women with breast cancer. Medical staffs can incorporate MBSR into clinical health education for patients with breast cancer to promote their overall quality of life.