1604 EVALUATION OF PREOPERATIVE SERUM CA19-9 AS PREDICTOR OF ADVERSE PATHOLOGIC FEATURES AND CLINICAL OUTCOME IN PATIENTS WITH UROTHELIAL CARCINOMA OF THE BLADDER UNDERGOING RADICAL CYSTECTOMY AND EXTENDED LYMPH NODE DISSECTION

2011 ◽  
Vol 185 (4S) ◽  
Author(s):  
Peter Jian ◽  
Guilherme Godoy ◽  
Gilad E. Amiel ◽  
Seth P. Lerner
Keyword(s):  
Lymph Node ◽  
Clinical Outcome ◽  
Urothelial Carcinoma ◽  
Radical Cystectomy ◽  
Lymph Node Dissection ◽  
Node Dissection ◽  
Extended Lymph Node Dissection ◽  
Preoperative Serum ◽  
Pathologic Features ◽  
Carcinoma Of The Bladder

1029 CHANGE IN PATHOLOGICAL N-STAGE ASSOCIATED WITH EXTENDED LYMPH NODE DISSECTION AND RADICAL CYSTECTOMY IN PATIENTS WITH UROTHELIAL CARCINOMA OF THE BLADDER

2010 ◽  
Vol 183 (4S) ◽  
Author(s):  
Guilherme Godoy ◽  
Lambros Stamatakis ◽  
Robert Freundlich ◽  
Guoqing Chen ◽  
Anuja Mital ◽  
...  
Keyword(s):  
Lymph Node ◽  
Urothelial Carcinoma ◽  
Radical Cystectomy ◽  
Lymph Node Dissection ◽  
Node Dissection ◽  
Extended Lymph Node Dissection ◽  
N Stage ◽  
Carcinoma Of The Bladder

scholarly journals Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients undergoing radical cystectomy

2019 ◽  
Author(s):  
Eu Chang Hwang ◽  
Niranjan J Sathianathen ◽  
Mari Imamura ◽  
Gretchen M Kuntz ◽  
Michael C Risk ◽  
...  
Keyword(s):  
Lymph Node ◽  
Urothelial Carcinoma ◽  
Radical Cystectomy ◽  
Lymph Node Dissection ◽  
Node Dissection ◽  
Carcinoma Of The Bladder

Surgical Pathology Findings in Patients Who Have Undergone Radical Cystectomy/Cystoprostatectomy With Extended Versus Standard Lymph Node Dissection for Urothelial Carcinoma of the Bladder: A Contemporary Analysis

2020 ◽  
pp. 106689692093707
Author(s):  
Joshua Kagan ◽  
Mehrdad Alemozaffar ◽  
Bradley Carthon ◽  
Adeboye O. Osunkoya
Keyword(s):  
Lymph Node ◽  
Neoadjuvant Chemotherapy ◽  
Lymph Nodes ◽  
Urothelial Carcinoma ◽  
Radical Cystectomy ◽  
Lymph Node Dissection ◽  
Detrusor Muscle ◽  
Node Dissection ◽  
Extended Lymph Node Dissection ◽  
Positive Lymph Nodes

Radical cystectomy/cystoprostatectomy with pelvic lymph node dissection (with or without neoadjuvant chemotherapy) is the gold standard in the management of patients with urothelial carcinoma (UCa) with muscularis propria (detrusor muscle) invasion. However, it remains controversial how extensive the lymph node dissection should be. In this article, we analyzed the clinicopathologic findings in patients who had radical cystectomy/cystoprostatectomy with extended versus standard lymph node dissection. A search was made through our Urologic Pathology files for radical cystectomy/cystoprostatectomy cases with extended and standard lymph node dissection for UCa. A total of 264 cases were included in the study (218 cystoprostatectomy and 46 cystectomy specimens). Mean patients age was 68 years (range = 32-92 years). Patients in all stage categories had more extended lymph node dissection performed compared with standard lymph node dissection: pT0 (20 vs 7), pTis (40 vs 12), pTa (8 vs 4), pT1 (27 vs 5), pT2 (39 vs 8), pT3 (51 vs 17), and pT4 (18 vs 8). In cases with neoadjuvant therapy there was a 19% lymph node positivity rate compared with a 24% positivity rate in those with no presurgical therapy. The only cases categorized as pT2 and below with positive lymph node metastasis were those that had extended lymph node dissection performed. Positive lymph nodes were more frequently detected in cases that had extended lymph node dissection. More than 35% of the positive lymph nodes were in nonregional distribution. Extended lymph node dissection should be considered in patients with UCa even in the low stage or post-neoadjuvant chemotherapy setting.

More Extensive Lymph Node Dissection Improves Survival Benefit of Radical Cystectomy in Metastatic Urothelial Carcinoma of the Bladder

2019 ◽  
Vol 17 (2) ◽  
pp. 105-113.e2 ◽  
Author(s):  
Elio Mazzone ◽  
Felix Preisser ◽  
Sebastiano Nazzani ◽  
Zhe Tian ◽  
Nicola Fossati ◽  
...  
Keyword(s):  
Lymph Node ◽  
Urothelial Carcinoma ◽  
Radical Cystectomy ◽  
Lymph Node Dissection ◽  
Survival Benefit ◽  
Node Dissection ◽  
Extensive Lymph Node Dissection ◽  
Metastatic Urothelial Carcinoma ◽  
Carcinoma Of The Bladder ◽  
Extensive Lymph Node

scholarly journals Bladder preserving approach for liposarcomatoid variant of transitional urothelial carcinoma

2015 ◽  
Vol 9 (11-12) ◽  
pp. 886
Author(s):  
Shrawan K Singh ◽  
Ankur Mittal ◽  
Abhinandan Mukhopadhyay ◽  
Nandita Kakkar ◽  
Debajyoti Chatterjee
Keyword(s):  
Lymph Node ◽  
Urothelial Carcinoma ◽  
Lymph Node Dissection ◽  
Transurethral Resection ◽  
Rare Case ◽  
Pelvic Lymph Node Dissection ◽  
Node Dissection ◽  
Carcinoma Of The Bladder ◽  
Worse Prognosis ◽  
Bladder Tumours

Urothelial carcinoma of the bladder with variant histologies is usually underdiagnosed and understaged. It is found in <25% of cases during transurethral resection of bladder tumours. The majority of cases carry worse prognosis, with higher rates of recurrence and progression, and should be managed agressively. Here, we report a rare case of liposarcomatoid variant of urothelial carcinoma managed by partial cystectomy and standard pelvic lymph node dissection

1406 EXTENDED LYMPH NODE DISSECTION IN PATIENTS UNDERGOING RADICAL CYSTECTOMY FOR CANCER: HOW HIGH?

2011 ◽  
Vol 185 (4S) ◽  
Author(s):  
Pascal Zehnder ◽  
Urs Studer ◽  
Eila Skinner ◽  
Ryan Dorin ◽  
Jie Cai ◽  
...  
Keyword(s):  
Lymph Node ◽  
Radical Cystectomy ◽  
Lymph Node Dissection ◽  
Node Dissection ◽  
Extended Lymph Node Dissection
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