Irreversible Electroporation for Treatment of Hepatocellular Carcinoma Adjacent to the Gallbladder

2016 ◽  
Vol 27 (7) ◽  
pp. 1093-1094 ◽  
Author(s):  
Sanna E. Herwald ◽  
Jonathan H. Chen ◽  
Ronald S. Arellano
Keyword(s):  
Hepatocellular Carcinoma ◽  
Irreversible Electroporation

scholarly journals Allogenic Natural Killer Cell Immunotherapy Combined with Irreversible Electroporation for Stage IV Hepatocellular Carcinoma: Survival Outcome

2018 ◽  
Vol 48 (5) ◽  
pp. 1882-1893 ◽  
Author(s):  
Mohammed Alnaggar ◽  
Mao Lin ◽  
Adnan Mesmar ◽  
Shuzhen Liang ◽  
Ammar Qaid ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Natural Killer ◽  
Nk Cell ◽  
Killer Cell ◽  
Irreversible Electroporation ◽  
Stage Iv ◽  
Clinical Effectiveness ◽  
Survival Outcome ◽  
Cell Immunotherapy

Background/Aims: We evaluated the clinical effectiveness of irreversible electroporation (IRE) in combination with immunotherapy using allogenic natural killer cells (NK) for stage IV hepatocellular carcinoma (HCC). Methods: The study involved 40 patients with stage IV HCC who were divided equally into two groups: 1) simple IRE; and 2) IRE plus allogenic NK cells (IRE-NK); we mainly assessed the overall survival (OS). Results: The effect of the IRE-NK treatment was synergistic, i.e., not only did it enhance immune function, it also decreased alpha-fetoprotein expression and showed significantly good clinical effectiveness. At the median 7.6-month follow-up (range, 3.8–12.1 months), median OS was higher in the IRE-NK group (10.1 months) than in the IRE group (8.9 months, P = 0.0078). Conclusion: IRE combined with allogeneic NK cell immunotherapy significantly increases the median OS of patients with stage IV HCC.

scholarly journals Evaluation of tolerability and efficacy of irreversible electroporation (IRE) in treatment of Child-Pugh B (7/8) hepatocellular carcinoma (HCC)

HPB ◽  
2016 ◽  
Vol 18 (7) ◽  
pp. 593-599 ◽  
Author(s):  
Neal Bhutiani ◽  
Prejesh Philips ◽  
Charles R. Scoggins ◽  
Kelly M. McMasters ◽  
Melissa H. Potts ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Irreversible Electroporation

scholarly journals Evaluation of tolerability and efficacy of irreversible electroporation (IRE) in treatment of child-pugh B (7/8) hepatocellular carcinoma (HCC)

HPB ◽  
2016 ◽  
Vol 18 ◽  
pp. e48
Author(s):  
N. Bhutiani ◽  
P. Philips ◽  
C. Scoggins ◽  
K. McMasters ◽  
M. Potts ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Irreversible Electroporation
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