The positive inotropic effect of the aqueous extract of Convallaria keiskei in beating rabbit atria

Life Sciences ◽  
2006 ◽  
Vol 79 (12) ◽  
pp. 1178-1185 ◽  
Author(s):  
Deok Ho Choi ◽  
Dae Gill Kang ◽  
Xun Cui ◽  
Kyung Woo Cho ◽  
Eun Jin Sohn ◽  
...  
2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Hao Zhen Cui ◽  
Dae Gill Kang ◽  
Seung Ju Kim ◽  
Deok Ho Choi ◽  
Kyung Woo Cho ◽  
...  

Author(s):  
Yun Jung Lee ◽  
Oh Jeong Kwon ◽  
Hye Yoom Kim ◽  
Seung Namgung ◽  
Jae Yun Lee ◽  
...  

1978 ◽  
Vol 235 (3) ◽  
pp. H295-H298
Author(s):  
J. G. Mill ◽  
D. V. Vassallo ◽  
P. Campanha Vde

The effects of uranyl ions on isometric contractions of atrial strips of rabbit heart were studied. It was observed that uranyl ions, in a concentration of 1.1 X 10(-5) M, do not alter isometric contraction; 2.2 X 10(-5) M concentration produced a small positive inotropic effect that was magnified at a 4.5 X 10(-5) M concentration; concentrations greater than 1.8 X 10(-5) M produced a negative inotropic effect. There is evidence that the positive inotropic effect is mediated by catecholamine release, in a similar manner to the action of uranyl ions on intestinal smooth muscle preparations. This response was blocked by propranolol and also after tyramine treatment of the preparation. The negative inotropic effect seems to be mediated by a blocking effect on calcium entry through the sarcolemma during activation. Indirect evidence supporting this hypothesis was the observation of a decrease of action of uranyl ions in the presence of isoproterenol and of increased extracellular calcium concentration.


2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Deok Ho Choi ◽  
Seung Ju Kim ◽  
Dae Gill Kang ◽  
Ho Sub Lee

2013 ◽  
Vol 16 (7) ◽  
pp. 633-640 ◽  
Author(s):  
Hao Zhen Cui ◽  
Hyun Cheol Oh ◽  
Xiang Li ◽  
Yun Jung Lee ◽  
Kyung Woo Cho ◽  
...  

Circulation ◽  
2003 ◽  
Vol 108 (13) ◽  
pp. 1633-1639 ◽  
Author(s):  
Rui-Ping Xiao ◽  
Sheng-Jun Zhang ◽  
Khalid Chakir ◽  
Pavel Avdonin ◽  
Weizhong Zhu ◽  
...  

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