A comparative study of encapsulation of carotenoid enriched-flaxseed oil and flaxseed oil by spray freeze-drying and spray drying techniques

LWT ◽  
2021 ◽  
Vol 143 ◽  
pp. 111153
Author(s):  
Aysel Elik ◽  
Derya Koçak Yanık ◽  
Fahrettin Göğüş
Keyword(s):  
Comparative Study ◽  
Spray Drying ◽  
Freeze Drying ◽  
Flaxseed Oil ◽  
Drying Techniques ◽  
Spray Freeze Drying

scholarly journals Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections

2016 ◽  
Vol 33 (6) ◽  
pp. 1486-1496 ◽  
Author(s):  
Sharon S. Y. Leung ◽  
Thaigarajan Parumasivam ◽  
Fiona G. Gao ◽  
Nicholas B. Carrigy ◽  
Reinhard Vehring ◽  
...  
Keyword(s):  
Spray Drying ◽  
Freeze Drying ◽  
Respiratory Infections ◽  
Drying Techniques ◽  
Spray Freeze Drying

scholarly journals Extended release promethazine HCl using acrylic polymers by freeze-drying and spray-drying techniques: formulation considerations

2009 ◽  
Vol 45 (4) ◽  
pp. 829-840 ◽  
Author(s):  
Ruchi Tiwari ◽  
Birendra Srivastava ◽  
Gaurav Tiwari ◽  
Awanik Rai
Keyword(s):  
Spray Drying ◽  
Freeze Drying ◽  
Extended Release ◽  
In Vitro Dissolution ◽  
Adsorptive Capacity ◽  
Acrylic Polymers ◽  
Dissolution Studies ◽  
Eudragit S100 ◽  
Drying Techniques

The present study investigated a novel extended release system of promethazine hydrochloride (PHC) with acrylic polymers Eudragit RL100 and Eudragit S100 in different weight ratios (1:1 and 1: 5), and in combination (0.5+1.5), using freeze-drying and spray-drying techniques. Solid dispersions were characterized by Fourier-transformed infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC), Powder X-ray diffractometry (PXRD), Nuclear magnetic resonance (NMR), Scanning electron microscopy (SEM), as well as solubility and in vitro dissolution studies in 0.1 N HCl (pH 1.2), double-distilled water and phosphate buffer (pH 7.4). Adsorption tests from drug solution to solid polymers were also performed. A selected solid dispersion system was developed into capsule dosage form and evaluated for in vitro dissolution studies. The progressive disappearance of drug peaks in thermotropic profiles of spray-dried dispersions were related to increasing amount of polymers, while SEM studies suggested homogenous dispersion of drug in polymer. Eudragit RL100 had a greater adsorptive capacity than Eudragit S100, and thus its combination in (0.5+1.5) for S100 and RL 100 exhibited a higher dissolution rate with 97.14% drug release for twelve hours. Among different formulations, capsules prepared by combination of acrylic polymers using spray-drying (1:0.5 + 1.5) displayed extended release of drug for twelve hours with 96.87% release followed by zero order kinetics (r²= 0.9986).

Poly(Lactide-Co-Glycolide) Microsphere Formulations of Darbepoetin Alfa: Spray Drying Is an Alternative to Encapsulation by Spray-Freeze Drying

2004 ◽  
Vol 21 (3) ◽  
pp. 500-506 ◽  
Author(s):  
Paul A. Burke ◽  
Lisa A. Klumb ◽  
John D. Herberger ◽  
Xichdao C. Nguyen ◽  
Roy A. Harrell ◽  
...  
Keyword(s):  
Spray Drying ◽  
Darbepoetin Alfa ◽  
Freeze Drying ◽  
Spray Freeze Drying
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